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anti-Human TSC1 antibody for Immunohistochemistry

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • hamartin
  • LAM
  • mKIAA0243
  • TSC
  • tsc1
  • wu:fc38b04
Epitope
C-Term
51
40
40
40
40
27
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
17
15
12
12
12
12
10
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
4
4
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
435
361
155
5
1
1
1
1
1
1
Host
Rabbit
730
45
18
1
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
4
4
4
4
3
3
3
3
3
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
532
491
156
63
33
32
20
16
12
7
4
2
1
Supplier
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Available images

Catalog No. ABIN256973
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22915025 ABIN2438267 IF IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal
0.22915025 ABIN2435921 IHC WB Goat Log in to see Polyclonal
0.0011319318 ABIN185619 IHC ELISA WB Goat C-Term Log in to see Polyclonal 3
0.0011319318 ABIN2466406 IHC ELISA WB Goat C-Term Log in to see Polyclonal
0.0011319318 ABIN251283 IHC (p) IHC ELISA WB Goat C-Term, Isoform 1 Log in to see Polyclonal
0.0011319318 ABIN2650961 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011319318 ABIN1824793 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011319318 ABIN1952932 IHC ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser505 Log in to see Polyclonal
0.0011319318 ABIN1953804 IHC ELISA APC Rabbit IgG Ser505 Log in to see Polyclonal
0.0011319318 ABIN1900963 IHC ELISA Alkaline Phosphatase (AP) Rabbit IgG C-Term Log in to see Polyclonal
0.0011319318 ABIN1900964 IHC ELISA APC Rabbit IgG C-Term Log in to see Polyclonal
0.0011319318 ABIN1900965 IHC ELISA Biotin Rabbit IgG C-Term Log in to see Polyclonal
0.0011319318 ABIN1900966 IHC ELISA PE Rabbit IgG C-Term Log in to see Polyclonal
0.0011319318 ABIN1900967 IHC ELISA FITC Rabbit IgG C-Term Log in to see Polyclonal
0.0011319318 ABIN1900971 ICC IHC ELISA WB APC Rabbit IgG Internal Region Log in to see Polyclonal
0.0011319318 ABIN1900972 ICC IHC ELISA WB FITC Rabbit IgG Internal Region Log in to see Polyclonal
0.0011319318 ABIN1900974 ICC IHC ELISA WB PE Rabbit IgG Internal Region Log in to see Polyclonal
0.0011319318 ABIN1900970 ICC IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Internal Region Log in to see Polyclonal
0.0011319318 ABIN1900973 ICC IHC ELISA WB Biotin Rabbit IgG Internal Region Log in to see Polyclonal
0.0011319318 ABIN1956246 IHC ELISA FITC Rabbit IgG Ser505 Log in to see Polyclonal

Top referenced anti-TSC1 antibody for Immunohistochemistry

  • Human Polyclonal TSC1 Primary Antibody for IHC, ELISA - ABIN185619 (3 Publications): Chan, Zhang, Roberts, Jozwiak, Wieslawa, Lewin-Kowalik, Kotulska, Kwiatkowski: Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation. in Journal of neuropathology and experimental neurology 2004 (PubMed)

Similar anti-TSC1 Antibodies

Application / Reactivity Mouse (Murine) Human
Dot Blot (DB) 247 Antibodies 209 Antibodies
ELISA 205 Antibodies 248 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 1 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 66 Antibodies

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope C-Term
(51), (40), (40), (40), (40), (27), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (17), (15), (12), (12), (12), (12), (10), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(435), (361), (155), (5), (1), (1), (1), (1), (1), (1)
Host Rabbit
(730), (45), (18), (1)
Clonality
Polyclonal
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (4), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(532), (491), (156), (63), (33), (32), (20), (16), (12), (7), (4), (2), (1)
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling Images
Cross-Reactivity (Details) Predicted cross-reactivity based on sequence identity: Mouse.
Purification affinity purified
Immunogen Synthetic peptide, 15 amino acid peptide from the carboxy terminus of human TSC1

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC1 (TSC1 Antibody Abstract)
Background Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberoussclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway.TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase ActivatingProtein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex hasbeen shown to inhibit mTor. Hamartin has also been shown to interact with ERM(Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins inmodulation of cell adhesion and morphology. Alternate Names: anti-TSC1 antibody, anti-HAMARTIN antibody, anti-KIAA0243 antibody, anti-LAMantibody, anti-MGC86987 antibody, anti-TSC antibody.
Gene Symbol: TSC1
Gene ID 7248, 64930
Pathways RTK Signaling, AMPK Signaling

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling Images back to top
Application Notes Recommended dilutions: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 5 µg/mL, Western Blot 4 µg/mL
Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Images back to top
Buffer PBS, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (C-Term) (ABIN256973) Heart: Formalin-Fixed Paraffin-Embedded (FFPE)