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anti-Mouse (Murine) TSC1 antibody for Immunoprecipitation

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • hamartin
  • LAM
  • mKIAA0243
  • TSC
  • tsc1
  • wu:fc38b04
Epitope
C-Term
51
40
40
40
40
27
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
17
15
12
12
12
12
10
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
4
4
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
435
361
155
5
1
1
1
1
1
1
Host
Rabbit
730
45
18
1
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
4
4
4
4
3
3
3
3
3
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
532
491
156
63
33
32
20
16
12
7
4
2
1
Supplier
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Available images

Catalog No. ABIN250696
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Similar anti-TSC1 Antibodies

Application / Reactivity Mouse (Murine) Human
Dot Blot (DB) 247 Antibodies 209 Antibodies
ELISA 205 Antibodies 248 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 1 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 66 Antibodies

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope C-Term
(51), (40), (40), (40), (40), (27), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (17), (15), (12), (12), (12), (12), (10), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(435), (361), (155), (5), (1), (1), (1), (1), (1), (1)
Host Rabbit
(730), (45), (18), (1)
Clonality
Polyclonal
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (4), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1)
Application Immunoprecipitation (IP), Western Blotting (WB)
(532), (491), (156), (63), (33), (32), (20), (16), (12), (7), (4), (2), (1)
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling Images
Cross-Reactivity (Details) Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill platypus, White-tufted-ear marmoset, Crab-eating macaque,Northern white-cheeked gibbon.
Purification affinity purified
Immunogen The immunogen recognized by this antibody maps to a region between residue 1100 and the C-terminus (residue 1164) of human tuberous sclerosis 1 using the numbering given in Swiss-Prot entry Q92574 (GeneID 7248).

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC1 (TSC1 Antibody Abstract)
Background The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarilyconserved serine/threonine kinase that regulates cell growth and cell cycle progressionthrough its ability to integrate signals from nutrient levels and growth factors. TORregulation is accomplished through a network of various activators and repressors. It isphosphorylated by Akt, whose activity is indirectly inhibited by the lipid phosphatasePTEN. TOR is normally associated with the regulatory proteins RAPTOR, a scaffoldprotein whose binding by TOR substrates is necessary for effective TOR-catalyzedphosphorylation, and GBetaL, which stimulates TOR’s kinase activity towardsdownstream proteins. It is further regulated by the proteins Rheb, TSC1 and TSC2,which act to modulate TOR activity. The downstream targets of TOR are thought to bethe ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins(4EBPs) whose activation leads to increased protein translation and cell growth. Alternate Names: anti-KIAA0243 antibody, anti-LAM antibody, anti-MGC86987 antibody, anti-TSCantibody, anti-Tuberous sclerosis protein 1 antibody.
Gene Symbol: TSC1
Gene ID 7248, 64930
Pathways RTK Signaling, AMPK Signaling

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling Images back to top
Application Notes Recommended dilutions: Immunoprecipitation 1-5 µg/mg lysate, Western Blot 1:5000-1:25000
Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Tris-citrate/Phosphate buffer, pH 7 to 8, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze.
Storage 4 °C

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (C-Term) (ABIN250696) Detection of Human and Mouse TSC1 by Western Blot and Immunoprecipitation. Samples: W...