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anti-Rat (Rattus) TSC1 antibody for Dot Blot

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • hamartin
  • LAM
  • mKIAA0243
  • TSC
  • tsc1
  • wu:fc38b04
Epitope
pSer312
52
40
40
40
39
27
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
17
15
12
12
12
12
10
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
4
4
3
3
3
2
2
1
1
1
1
Reactivity
Rat (Rattus)
437
363
154
5
1
1
1
1
1
1
Host
Rabbit
731
45
18
1
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
4
4
4
4
3
3
3
3
3
1
1
1
Application
Dot Blot (DB)
531
491
158
64
33
33
20
16
12
8
4
2
1
Supplier
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Catalog No. ABIN1881907
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.63784635 ABIN1881908 DB Rabbit pThr417 Log in to see Polyclonal 5
0.63784635 ABIN1881909 DB Rabbit pTyr297 Log in to see Polyclonal 5
0.63784635 ABIN1881906 DB Rabbit pSer1141 Log in to see Polyclonal 5
0.63784635 ABIN2491729 DB Rabbit Ig Fraction pSer1141 Log in to see Polyclonal
0.63784635 ABIN2491731 DB Rabbit Ig Fraction pTyr297 Log in to see Polyclonal
0.63784635 ABIN2491730 DB Rabbit Ig Fraction pSer312 Log in to see Polyclonal
0.63784635 ABIN2491732 DB Rabbit Ig Fraction pThr417 Log in to see Polyclonal
0.0008934913 ABIN1968099 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1141, pSer1141 Log in to see Polyclonal
0.0008934913 ABIN1968103 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser312, pSer312 Log in to see Polyclonal
0.0008934913 ABIN1968108 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Thr417, pThr417 Log in to see Polyclonal
0.0008934913 ABIN1968109 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Tyr297, pTyr297 Log in to see Polyclonal
0.0008934913 ABIN1968121 DB ELISA APC Rabbit IgG Ser1141, pSer1141 Log in to see Polyclonal
0.0008934913 ABIN1968125 DB ELISA APC Rabbit IgG Ser312, pSer312 Log in to see Polyclonal
0.0008934913 ABIN1968130 DB ELISA APC Rabbit IgG Thr417, pThr417 Log in to see Polyclonal
0.0008934913 ABIN1968131 DB ELISA APC Rabbit IgG Tyr297, pTyr297 Log in to see Polyclonal
0.0008934913 ABIN1968215 DB ELISA Biotin Rabbit IgG Ser1141, pSer1141 Log in to see Polyclonal
0.0008934913 ABIN1968219 DB ELISA Biotin Rabbit IgG Ser312, pSer312 Log in to see Polyclonal
0.0008934913 ABIN1968224 DB ELISA Biotin Rabbit IgG Thr417, pThr417 Log in to see Polyclonal
0.0008934913 ABIN1968225 DB ELISA Biotin Rabbit IgG Tyr297, pTyr297 Log in to see Polyclonal
0.0008934913 ABIN1968242 DB ELISA FITC Rabbit IgG Ser1141, pSer1141 Log in to see Polyclonal

Top referenced anti-TSC1 antibody for Dot Blot

Similar anti-TSC1 Antibodies

Application / Reactivity Rat (Rattus)
Dot Blot (DB) 76 Antibodies
ELISA 71 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Western Blotting (WB) 42 Antibodies

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope pSer312
(52), (40), (40), (40), (39), (27), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (17), (15), (12), (12), (12), (12), (10), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(437), (363), (154), (5), (1), (1), (1), (1), (1), (1)
Host Rabbit
(731), (45), (18), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (4), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1)
Application Dot Blot (DB)
(531), (491), (158), (64), (33), (33), (20), (16), (12), (8), (4), (2), (1)
Pubmed 5 references available
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling References for anti-TSC1 Antibody (ABIN1881907) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1.
Clone RB41267

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling References for anti-TSC1 Antibody (ABIN1881907) Images back to top
Antigen
Alternative Name TSC1 (TSC1 Antibody Abstract)
Background In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Synonyms: Tsc1, Hamartin, Tuberous sclerosis 1 protein homolog
NCBI Accession NP_068626
UniProt Q9Z136
Pathways RTK Signaling, AMPK Signaling

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling References for anti-TSC1 Antibody (ABIN1881907) Images back to top
Application Notes DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details References for anti-TSC1 Antibody (ABIN1881907) Images back to top
Format Liquid
Concentration 0.32 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-TSC1 Antibody (ABIN1881907)

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling Images back to top
Product cited in:

Inoue, Ndong, Suzuki, Kazami, Uyama, Kobayashi, Tadokoro, Yamamoto: "Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, 2009

Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, 2009

Chen, Yan, Chen, He: "The variation of AkT/TSC1-TSC1/mTOR signal pathway in hepatocytes after partial hepatectomy in rats." in: Experimental and molecular pathology, Vol. 86, Issue 2, pp. 101-7, 2009

Momose, Kobayashi, Tada, Itoyama, Hino: "N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo." in: Biochemical and biophysical research communications, Vol. 356, Issue 3, pp. 693-8, 2007

Background publications

Goncharova, Goncharov, Noonan, Krymskaya: "TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase." in: The Journal of cell biology, Vol. 167, Issue 6, pp. 1171-82, 2004

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling References for anti-TSC1 Antibody (ABIN1881907) back to top
Supplier Images
Dot Blot (DB) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (pSer312) (ABIN1881907) Dot blot analysis of rat TSC1 Antibody (Phospho S312) Phospho-specific Pab (ABIN18819...