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Browse our Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Proteins (SLC1A3)

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Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Proteins (SLC1A3)
On www.antibodies-online.com are 6 Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) Proteins from 3 different suppliers available. Additionally we are shipping Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Antibodies (102) and Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Kits (13) and many more products for this protein. A total of 126 Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 products are currently listed.
Synonyms:
AF001784, AI504299, B430115D02Rik, CG3747, dEAAT, dEaat1, Dglt-1, Dglut-1, Dmel\\CG3747, EA6, EAAT, Eaat1, GLAST, GLAST-1, GLAST1, GLU-T, GluT-1, Gmt1, MGluT1, SLC1A3, wu:fb98e05, wu:fd50b05, zgc:56661, zgc:77768
list all proteins Gene Name GeneID UniProt
SLC1A3 29483 P24942
SLC1A3 6507 P43003
SLC1A3 20512 P56564

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Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Proteins (SLC1A3) by Origin

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More Proteins for Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Interaction Partners

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. Eaat1 expression is promoted by Fringe-mediated neuron-glial communication during development and suggest that Eaat1 plays an essential role in regulating central nervous system neural circuits that control locomotion in Drosophila

  2. dEAAT1 is present at the adult, but surprisingly not at embryonic and larval NMJ, suggesting a physiological maturation of the junction during metamorphosis

Human Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. A heterozygous SLC1A3 c.1177G4A mutation has been detected in a patient with late-onset episodic ataxia (show USP14 Proteins). Same heterozygous mutation was identified in one clinically affected family member and two asymptomatic members.

  2. that Abeta1-42 oligomers could cause disturbances in insulin (show INS Proteins)/Akt (show AKT1 Proteins)/EAAT (show SLC1A2 Proteins) signaling in astrocytes

  3. We consider an association between SLC1A3 and the behavioural problems which can also be considered a contributing factor to behavioural problems in larger duplications overlapping the 5p13 microduplication syndrome region.

  4. In combination with other nearby residues, Arg-388 coordinates anion channel gating and forms part of the missing structural link between the anion conducting and substrate transport states in EAAT1.

  5. SPAK (show STK39 Proteins) and OSR1 (show OXSR1 Proteins) are powerful negative regulators of the excitatory glutamate (show GRIN1 Proteins) transporters EAAT1 and EAAT2 (show SLC1A2 Proteins).

  6. There was no association between pyramidal cell EAAT1 splice variant expression and schizophrenia.

  7. data provide additional insights into the mechanism by which substrates gate the anion conductance in EAATs and suggest that in EAAT1, Arg-388 is a critical element for the structural coupling between the substrate translocation and the gating mechanisms

  8. discovering compounds that can enhance EAAT1 expression and activity may be a novel strategy for therapeutic treatment of glaucoma.

  9. Results showed that EAAT2 (show SLC1A2 Proteins) levels were significantly decreased in the essential tremor cerebellar cortex, in contrast to similar levels of EAAT1 levels between essential tremor cases and controls

  10. EAAT1 polymorphism which is involved in the Regulation of extracellular glutamate (show GRIN1 Proteins) concentrations, influences Cognitive performances with a detrimental effect of T/T homozygosis.

Mouse (Murine) Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. SLC1A3 maintains a constant import of acidic amino acids independently of nutritional status in adipocytes.

  2. glutamate/aspartate transporter (GLAST) was elevated in 8- to 10- and/or 20- to 22-month GHR (show GHR Proteins)-KO mice when comparing genotypes

  3. This study findings demonstrate that Ascl1 (show ASCL1 Proteins)(CreERT2) and Glast(CreERT2) mouse lines enable simple and reliable labeling of adult-born GC lineages within restricted time windows.

  4. arundic acid treatment prevented RGC death by upregulating GLAST in heterozygous (GLAST(+/-)) mice

  5. Results show that expression of GLAST is decreased in cerebellar astrocytes in a mouse model of SCA1; decrease occurs in non-cell autonomous manner late in disease and correlates well with the loss of Purkinje neurons

  6. we have demonstrated for the first time that DOR receptor activation induces astrocytic expression of EAAT1 and EAAT2 (show SLC1A2 Proteins)

  7. The result showed significant correlation between changes in GLUT 8 (show SLC2A8 Proteins) and glucose levels with changes in StAR level in the testis and circulating testosterone level in the mice from birth to senescence

  8. EAAT1 activity and sodium potassium-ATPase activity are co-regulated by a tightly coupled homeostatic relationship in astrocytes.

  9. Study suggests that there is a remarkable subcellular heterogeneity of GLAST and GLT-1 expression in the developing hippocampus

  10. TNR (show TNR Proteins) is expressed in a subset of astrocytes and contributes to glutamate (show GRIN1 Proteins) homeostasis by regulating astrocytic GLAST expression.

Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) Protein Profile

Protein Summary

This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3)

  • Excitatory amino acid transporter 1 (Eaat1)
  • excitatory amino acid transporter 1 (EAAT1)
  • excitatory amino acid transporter 1 (PTRG_00379)
  • excitatory amino acid transporter 1 (Tsp_02392)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3a (slc1a3a)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3 (Slc1a3)
  • AF001784 protein
  • AI504299 protein
  • B430115D02Rik protein
  • CG3747 protein
  • dEAAT protein
  • dEaat1 protein
  • Dglt-1 protein
  • Dglut-1 protein
  • Dmel\\CG3747 protein
  • EA6 protein
  • EAAT protein
  • Eaat1 protein
  • GLAST protein
  • GLAST-1 protein
  • GLAST1 protein
  • GLU-T protein
  • GluT-1 protein
  • Gmt1 protein
  • MGluT1 protein
  • SLC1A3 protein
  • wu:fb98e05 protein
  • wu:fd50b05 protein
  • zgc:56661 protein
  • zgc:77768 protein

Protein level used designations for SLC1A3

CG3747-PA , CG3747-PB , CG3747-PC , CG3747-PD , Eaat1-PA , Eaat1-PB , Eaat1-PC , Eaat1-PD , drosophila glutamate transporter-1 , excitatory amino acid transporter 1 , glutamate transporter , sodium-dependent excitatory amino acid transporter 1 , sodium-dependent glutamate transporter , sodium-excitatory-glutamate-cotransporter , EAAT1A , excitatory amino acid transporter SLC1A3a , glasta , solute carrier family 1 (glial high affinity glutamate transporter), member 3 , Na+-dependent glutamate/aspartate transporter , Sodium-dependent glutamate/aspartate transporter 1 , excitatory amino acid transporter 1-like , GLAST-1 , glial glutamate transporter , glutamate/aspartate transporter , sodium-dependent glutamate/aspartate transporter 1 , solute carrier family 1, member 3 , solute carrier family 1 member 3 , glial high affinity glutamate transporter , high-affinity neuronal glutamate transporter

GENE ID SPECIES
34251 Drosophila melanogaster
443246 Ovis aries
6340496 Pyrenophora tritici-repentis Pt-1C-BFP
10908153 Trichinella spiralis
323439 Danio rerio
395443 Gallus gallus
461918 Pan troglodytes
701109 Macaca mulatta
100014533 Monodelphis domestica
100408230 Callithrix jacchus
100433620 Pongo abelii
100479747 Ailuropoda melanoleuca
100587553 Nomascus leucogenys
29483 Rattus norvegicus
6507 Homo sapiens
20512 Mus musculus
282354 Bos taurus
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