Browse our anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Antibodies

Full name:
anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies (CHRNA1)
On www.antibodies-online.com are 92 Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Antibodies from 17 different suppliers available. Additionally we are shipping Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Kits (22) and Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Proteins (18) and many more products for this protein. A total of 140 Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) products are currently listed.
Synonyms:
Achr-1, ACHRA, ACHRD, Acra, AI385656, AI608266, CHRNA, CHRNA1, CMS2A, FCCMS, NACHRA1, SCCMS
list all antibodies Gene Name GeneID UniProt
CHRNA1 1134 P02708
CHRNA1 79557 P25108
CHRNA1 11435 P04756

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All available anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies

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Top referenced anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies

  1. Mouse (Murine) Monoclonal CHRNA1 Primary Antibody for IF, WB - ABIN968298 : Garchon, Djabiri, Viard, Gajdos, Bach: Involvement of human muscle acetylcholine receptor alpha-subunit gene (CHRNA) in susceptibility to myasthenia gravis. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 5 references for 968298

  2. Cow (Bovine) Polyclonal CHRNA1 Primary Antibody for WB - ABIN2776079 : Webster, Brydson, Croxen, Newsom-Davis, Vincent, Beeson: Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome. in Neurology 2004 (PubMed)

More Antibodies against Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. Data suggest that the mutations made the cholinergic receptor nicotinic alpha 1 subunit channel (CHRNA1) resistant to the antagonists, not by impairing antagonist binding, but rather by producing a gain-of-function phenotype, e.g. increased agonist sensitivity.

  2. Study indicated that nicotinic acetylcholine receptor alpha 1-subunit peptides may act as receptor decoy molecules and inhibit the binding of virus to the native host cell receptors and hence may reduce viral infection.

  3. ChRnA1 gene variants did not affect the pharmacodynamics of rocuronium.

  4. Cholesterol and CAV-1 (show CAV1 Antibodies) modulate the function and dynamics of the slow channel congenital myasthenia syndrome alphaC418W nicotinic acetylcholine receptor mutation.

  5. nicotine contributes to the progression and erlotinib-resistance of the NSCLC xenograft model via the cooperation between nAChR (show CHRNA4 Antibodies) and EGFR (show EGFR Antibodies).

  6. show that AON complementary to the 5' splice site of the exon was the most effective at exon skipping of the minigene with causative mutations, as well as endogenous wild-type CHRNA1

  7. The CHRNA1 extracellular domain is an improved protein for use in antigen-specific Myasthenia Gravis therapeutic strategies.

  8. HnRNP L (show HNRNPL Antibodies) and hnRNP (show HNRNPC Antibodies) LL antagonistically modulate PTB (show PTBP1 Antibodies)-mediated splicing suppression of CHRNA1 pre-mRNA.

  9. High expression of CHRNA1 is associated with lung adenocarcinoma after complete resection.

  10. No mutations were found in CHRNG (show CHRNG Antibodies), CHRND (show CHRND Antibodies) and CHRNA1 genes of Indian families with Escobar syndrome.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. The results indicate that in the absence of the alpha1-nAChR (show CHRNA4 Antibodies) subunit, clusters of nAChRs coupled to SK2 (show PAPSS2 Antibodies) potassium channels as well as functional efferent synapses did form, showing that alpha1 is not necessary for these processes to take place.

  2. This study demonstrates that genes coding for CHRNA1 subunits may contain variants associated with statin-induced ADRs.

  3. Chrna1 was co-purified with nicotinic acetylcholine receptor (AChR) in C2C12 myotubes. In addition, Stau1 (show STAU1 Antibodies) was found to interact with Chrna1 mRNA, and knocking down of Stau1 (show STAU1 Antibodies) by RNAi resulted in defective AChR clustering.

  4. These results suggest that in skeletal muscle cells, neural activity reduces the molar ratio of YB-1 (show YBX1 Antibodies) relative to its binding AChR alpha mRNA, leading to an increase of ribosome binding to the mRNA, and thus activating translation.

  5. Chrna1 could be the first transcriptional target of atonal homolog 1 in the inner ear

  6. These data identify caveolin-3 (show CAV3 Antibodies) as a critical component of the signaling machinery that drives nicotinic acetylcholine receptor clustering and controls neuromuscular junction function.

  7. HDAC4 (show HDAC5 Antibodies) is a neural activity-regulated deacetylase and a key signaling component that relays neural activity to the muscle transcriptional machinery through Dach2 (show DACH2 Antibodies), myogenin (show MYOG Antibodies), and nAChR (show CHRNA4 Antibodies)

  8. In S269I, mutant the peak-current amplitude decreases along trains of nearly saturating ACh (show FGFR3 Antibodies) pulses delivered at physiologically relevant frequencies, consistent with enhanced entry into desensitization in congenital myasthenic syndrome.

  9. In this mouse experiemntal myasthenia gravis study demonstrated that Acetylcholine receptor-alpha1 subunit expression was increase with varying disease severity.

Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Antigen Profile

Antigen Summary

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1)

  • acetylcholine receptor alpha subunit (ACHR) antibody
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (CHRNA1) antibody
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (Chrna1) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) (Chrna1) antibody
  • Achr-1 antibody
  • ACHRA antibody
  • ACHRD antibody
  • Acra antibody
  • AI385656 antibody
  • AI608266 antibody
  • CHRNA antibody
  • CHRNA1 antibody
  • CMS2A antibody
  • FCCMS antibody
  • NACHRA1 antibody
  • SCCMS antibody

Protein level used designations for CHRNA1

acetylcholine receptor subunit alpha , acetylcholine receptor, nicotinic, alpha 1 (muscle) , cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , muscle nicotinic acetylcholine receptor , nicotinic acetylcholine receptor alpha subunit , nicotinic cholinergic receptor alpha 1 , muscle nicotinic acetylcholine receptor alpha-su exon P4 , nachr alpha-subunit , nicotinic acetylcholine recepter alpha-subunit , cholinergic receptor nicotinic alpha polypeptide 1 , alpha-1 subunit, nicotinic acetylcholine receptor , nicotinic cholinergic receptor alpha polypeptide 1

GENE ID SPECIES
751106 Felis catus
1134 Homo sapiens
403757 Canis lupus familiaris
338070 Bos taurus
79557 Rattus norvegicus
395608 Gallus gallus
396587 Sus scrofa
101110120 Ovis aries
11435 Mus musculus
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