Browse our Plexin A1 Proteins (PLXNA1)

On are 7 Plexin A1 (PLXNA1) Proteins from 3 different suppliers available. Additionally we are shipping Plexin A1 Antibodies (39) and many more products for this protein. A total of 46 Plexin A1 products are currently listed.
2600013D04Rik, mKIAA4053, NOV, NOVP, PlexA1, PLEXIN-A1, Plxn1, PLXNA1
list all proteins Gene Name GeneID UniProt
PLXNA1 5361 Q9UIW2
PLXNA1 18844 P70206
Rat PLXNA1 PLXNA1 362398  

Plexin A1 Proteins (PLXNA1) by Origin

More Proteins for Plexin A1 Interaction Partners

Xenopus laevis Plexin A1 (PLXNA1) interaction partners

  1. Neuropilin-1 (show NRP1 Proteins) and its co-receptor plexinA1 are necessary to bias the extension of the dendrites of retinal ganglion cells to the apical side of the cell, and ectopically expressed class III semaphorins (Sema3s) disrupt this process.

Human Plexin A1 (PLXNA1) interaction partners

  1. We thus screened 250 patients for the presence of mutations in PLXNA1, and identified different nonsynonymous mutations (p.V349L, p.V437L, p.R528W, p.H684Y, p.G720E, p.R740H, p.R813H, p.R840Q, p.A854T, p.R897H, p.L1464V, p.K1618T, p.C1744F), all at heterozygous state, in 15 patients.

  2. Semaphorin-3a (show SEMA3A Proteins), neuropilin-1 (show NRP1 Proteins) and plexin-A1 are axonal guidance molecules that have been recently implicated in regulating bone metabolism.

  3. a novel mutation in the PLXNA1 receptor (c.2587G>A) in newly established pancreatic cell line, is reported.

  4. Data indicate that plexin A1-4 (PLXNA1-4) mediation of neuroanatomical traits can be detected using in vivo neuroimaging techniques.

  5. neuropilin 1 (show NRP1 Proteins) and plexin A1 transmembrane domains interaction

  6. Expression of Plexin A1 in gastric carcinoma was significantly higher than that in normal gastric mucosa.

  7. Breast carcinoma cells support an autocrine pathway involving SEMA3A (show SEMA3A Proteins), plexin-A1, and NP1 (show NPX1 Proteins) that impedes their ability to chemotax.

  8. PlexinA1 may play an important role in the occurrence and development of gastric carcinoma, and be related to tumor angiogenesis and proliferation.

  9. In malignant pleural mesothelioma cells, plexin-A1 and VEGF-receptor 2 (VEGF-R2) are associated in a complex which are involved in survival pathways.

  10. Data show that the expression of Sema3A (show SEMA3A Proteins) receptors (neuropilin-1 (NRP-1 (show NRP1 Proteins)), NRP-2 (show NELL2 Proteins), plexin A1, plexin A2 (show Plxna2 Proteins), and plexin A3 (show PLXNA3 Proteins)) significantly increased during M-CSF (show CSF1 Proteins)-mediated differentiation of monocytes into macrophages.

Mouse (Murine) Plexin A1 (PLXNA1) interaction partners

  1. PLXNA1 mediates the acquisition of malignant phenotypes induced by autocrine SEMA3A (show SEMA3A Proteins) signaling in lung cancer cells.

  2. Study showed that progenitor cells lining the telencephalic ventricles express PlexinA1 and that absence of this receptor impairs neurogenesis in the developing forebrain

  3. PlexinA1 mediates both Semaphorin and Slit signaling

  4. genetic findings demonstrate that Sema3a (show SEMA3A Proteins) repellent signaling plays a role in the establishment of proper afferent projections in SAG (show RNF7 Proteins) neurons, and this signaling likely occurs through a receptor complex involving Npn1 (show NRP1 Proteins) and either plexinA1 or plexinA3 (show PLXNA3 Proteins)

  5. A novel direct interaction between the Sema3a (show SEMA3A Proteins) signaling receptor plexinA1 and nephrin (show NPHS1 Proteins), linking extracellular Sema3a (show SEMA3A Proteins) signals to the slit-diaphragm signaling complex, was identified.

  6. Data demonstrate an essential direct function of Sema3A (show SEMA3A Proteins)-Nrp1 (show NRP1 Proteins)-PlexinA1 signaling in lymphatic valve formation.

  7. These findings suggest a mechanism by which a complex of Sema6D (show SEMA6D Proteins), Nr-CAM (show NRCAM Proteins), and Plexin-A1 at the chiasm midline alters the sign of Sema6D (show SEMA6D Proteins) and signals Nr-CAM (show NRCAM Proteins)/Plexin-A1 receptors on retinal ganglion cells to implement the contralateral retinal cell projection.

  8. Results suggest that plexin-A1 and B1 interact in the adult brain and transduce semaphorin 3A (show SEMA3A Proteins) signaling in cooperation.

  9. Plexin-A1 affects t-cell-dendritic cell interaction but not antigen processing or binding.

  10. Plexin-A1 forms a receptor complex with vascular endothelial growth factor receptor type 2 in heart morphogenesis

Plexin A1 (PLXNA1) Protein Profile

Protein Summary

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm.

Alternative names and synonyms associated with Plexin A1 (PLXNA1)

  • plexin A1 (PLXNA1)
  • plexin A1 (plxna1)
  • plexin A1 (Plxna1)
  • similar to plexin 1 (RGD1560871)
  • 2600013D04Rik protein
  • mKIAA4053 protein
  • NOV protein
  • NOVP protein
  • PlexA1 protein
  • PLEXIN-A1 protein
  • Plxn1 protein
  • PLXNA1 protein

Protein level used designations for Plexin A1 Proteins (PLXNA1)

plexin A1 , plexin A1a , plexin-A1 , plexin 1 , semaphorin receptor NOV , plex 1 , plexin-1

100060411 Equus caballus
397805 Xenopus laevis
416030 Gallus gallus
460665 Pan troglodytes
531240 Bos taurus
558065 Danio rerio
100037845 Xenopus (Silurana) tropicalis
100589116 Nomascus leucogenys
5361 Homo sapiens
18844 Mus musculus
100688869 Canis lupus familiaris
100624579 Sus scrofa
100724160 Cavia porcellus
362398 Rattus norvegicus
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