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Browse our Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Proteins (SPI1)

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Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Proteins (SPI1)
On www.antibodies-online.com are 12 Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Proteins from 6 different suppliers available. Additionally we are shipping Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Antibodies (148) and Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Kits (9) and many more products for this protein. A total of 180 Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 products are currently listed.
Synonyms:
2B1, Ab1-021, cb1086, CPi-23, Dis-1, Dis1, Gm5657, OF, pu.1, pu1, Serpina3d, Serpina3l, Sfpi-1, sfpi1, si:by184l24.2, Spi-1, SPI-A, SPI1, Spin1, Spin2a, Tcfpu1, Tfpu.1
list all proteins Gene Name GeneID UniProt
SPI1 435318  
Rat SPI1 SPI1 299282  
SPI1 6688 P17947

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Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Proteins (SPI1) by Origin

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More Proteins for Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Interaction Partners

Mouse (Murine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. findings suggest that Gata1 (show GATA1 Proteins) & PU.1 transcription factors are only executing and reinforcing lineage choice once made. These results challenge the current prevailing model of early myeloid lineage choice

  2. involved in osteoclast development by transactivating NFATc1 (show NFATC1 Proteins) expression via direct binding to the NFATc1 (show NFATC1 Proteins) promoter

  3. GATA1 (show GATA1 Proteins) and PU.1 bind in vitro and in vivo the proximal promoter region of the RPS19 (show RPS19 Proteins) gene which is frequently mutated in Diamond-Blackfan Anemia.

  4. PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 (show GATA3 Proteins) Transcription in Dendritic Cells

  5. Taken together, our results suggest that the expression of NDRG2 (show NDRG2 Proteins) potentially inhibits osteoclast differentiation and plays a role in modulating the signal transduction pathway responsible for osteoclastogenesis.

  6. Our results suggest that complementary biological functions of PU.1 and Spi-B (show SPIB Proteins) may be explained by their interaction with a similar set of regions in the genome of B cells.

  7. PU.1 keeps macrophage-specific genes accessible during differentiation by preventing Polycomb (show CBX2 Proteins) repressive complex 2 binding to transcriptional regulatory elements.

  8. Nfkb1 (show NFKB1 Proteins) transcriptional activation by PU.1 and Spi-B (show SPIB Proteins) promotes toll (show TLR4 Proteins)-like receptor-mediated B cell proliferation.

  9. These findings indicate that PU.1-mediated upregulation of CSF-1R (show CSF1R Proteins) is a critical effector of MLL (show MLL Proteins) leukemogenesis.

  10. The Nogo-B (show RTN4 Proteins)-PirB (show LILRB3 Proteins) axis controls macrophage-mediated vascular remodeling.

Human Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. we conclude that PU.1 transactivates the pIII through direct binding to Ets (show ETS1 Proteins)-motifs in the promoter in pDCs

  2. Our results suggest the existence of a Vav1 (show VAV1 Proteins)/PU.1/miR (show MLXIP Proteins)-142-3p network that supports all-trans retinoic acid -induced differentiation in acute promyelocytic leukemia (show PML Proteins) -derived cells

  3. Our data suggest that E2A (show TCF3 Proteins) antagonism of PU.1 activity contributes to its ability to commit multipotential hematopoietic progenitors to the lymphoid lineages.

  4. This study showed that HCV infection might abrogate NK cytotoxic potential through altering PU.1, NKG2D (show KLRK1 Proteins) receptor and perforin (show PRF1 Proteins) molecules.

  5. SPI1-GFI1B (show GFI1B Proteins) transcriptional network is an important regulatory axis in acute myeloid leukemia (show BCL11A Proteins) as well as in the development of erythroid versus myelomonocytic cell fate

  6. The GATA-1-mediated inhibition of PU.1 gene transcription in human AML-erythroleukemias mediated through the URE represents important mechanism that contributes to PU.1 downregulation and leukemogenesis that is sensitive to DNA demethylation therapy

  7. PU.1 downregulation was noted in B-CLL/SLL (show SLC35B2 Proteins) samples positive for the adverse prognostic markers CD38 and ZAP-70 (show ZAP70 Proteins).

  8. This study demonstrated positive regulation of monocyte/macrophage differentiation by lnc-MC and uncovered an elaborate regulation mechanism composed of PU.1, lnc-MC, miR (show MLXIP Proteins)-199a-5p, and ACVR1B (show ACVR1B Proteins).

  9. Collectively, IMiDs exert demethylation activity through inhibiting DNMT1 (show DNMT1 Proteins), 3a, and 3b, and up-regulating PU.1 expression, which may be one of the mechanisms of the anti-myeloma activity of IMiDs.

  10. PU.1 suppressive target gene, metallothionein 1G (show MT1G Proteins), inhibits retinoic acid-induced NB4 cell differentiation.

Pig (Porcine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

Zebrafish Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. eaf1 (show EAF1 Proteins) has a role in suppressing foxo3b expression to modulate transcriptional activity of gata1 (show GATA1 Proteins) and spi1 in primitive hematopoiesis

  2. Our results indicate that Kzp (show ANPEP Proteins) is a critical transcriptional factor for the expression of gata2 and pu.1 to modulate primitive hematopoiesis.

  3. Runx1 (show RUNX1 Proteins) is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  4. The authors show that tif1gamma (show TRIM33 Proteins) modulates the erythroid versus myeloid fate outcomes from HSCs by differentially controlling the levels of gata1 (show GATA1 Proteins) and pu.1.

  5. found a gene group downregulated on spi1 knockdown,containing all 5 previously identified Spi1-dependent genes as well as a large set of novel immune-related genes

  6. In zebrafish, spi1 marks a rostral population of LPM cells committed to a myeloid fate anatomically separated from and developmentally independent of erythroid commitment in the caudal LPM.

Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Protein Profile

Protein Summary

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1)

  • serine (or cysteine) peptidase inhibitor, clade A, member 3D, pseudogene (Serpina3d-ps)
  • Serine protease inhibitor (LOC299282)
  • spleen focus forming virus (SFFV) proviral integration oncogene (SPI1)
  • spleen focus forming virus (SFFV) proviral integration oncogene (Spi1)
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1)
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1b (spi1b)
  • 2B1 protein
  • Ab1-021 protein
  • cb1086 protein
  • CPi-23 protein
  • Dis-1 protein
  • Dis1 protein
  • Gm5657 protein
  • OF protein
  • pu.1 protein
  • pu1 protein
  • Serpina3d protein
  • Serpina3l protein
  • Sfpi-1 protein
  • sfpi1 protein
  • si:by184l24.2 protein
  • Spi-1 protein
  • SPI-A protein
  • SPI1 protein
  • Spin1 protein
  • Spin2a protein
  • Tcfpu1 protein
  • Tfpu.1 protein

Protein level used designations for SPI1

SPI-1 , SPI-2.1 , contrapsin-like protease inhibitor 3 , contrapsin-like protease inhibitor-related protein , liver regeneration protein lrryan , serine protease inhibitor 1 , serine protease inhibitor 2.1 , serine protease inhibitor 2a , serine protease inhibitor A3L , serpin A3L , 31 kDa transforming protein , 31 kDa-transforming protein , SPI-1 proto-oncogene , hematopoietic transcription factor PU.1 , spleen focus forming virus (SFFV) proviral integration oncogene spi1 , transcription factor PU.1 , SFFV proviral integration 1 protein , SFFV proviral integration 1 , spleen focus forming virus proviral integration oncogene spi1 , Spi-1/PU.1 transcription factor , transcription factor spi1

GENE ID SPECIES
435318 Mus musculus
299282 Rattus norvegicus
6688 Homo sapiens
20375 Mus musculus
366126 Rattus norvegicus
395879 Gallus gallus
611255 Canis lupus familiaris
414912 Sus scrofa
507100 Bos taurus
30117 Danio rerio
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