anti-Mouse (Murine) BCL10 antibody for ELISA

Recommended BCL10 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 10 (BCL10) Antibodies
  • CARMEN
  • CIPER
  • CLAP
  • c-E10
  • mE10
  • BCL10
  • AI132454
  • BCL-10
  • C81403
  • ME10
  • cE10
  • bcl10
  • B-cell CLL/lymphoma 10
  • B cell leukemia/lymphoma 10
  • B-cell lymphoma/leukemia 10
  • BCL10
  • Bcl10
  • bcl10
  • LOC100223183
Reactivity
Human, Mouse (Murine)
300
93
48
2
2
1
1
1
1
1
1
1
Host
Mouse
174
123
4
Clonality
Monoclonal
Conjugate
This BCL10 antibody is un-conjugated
11
10
10
8
6
5
4
4
4
4
4
4
4
4
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
232
137
115
109
96
88
59
33
26
13
3
3
2
2
Options
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Catalog No. ABIN2869148
$ 428.57
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1534429 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN4283294 CyTOF ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see 4F8 1
1 ABIN1724629 ICC FACS IHC ELISA WB Mouse IgG1 Log in to see 4F8 3
1 ABIN3183496 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN4283295 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN3209988 FACS IF IHC ELISA WB Mouse IgG1 Log in to see 4F8E8H8-4F8E3H8
1 ABIN1820372 ICC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1963501 ELISA FACS ICC IF IHC WB APC Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN1966165 ELISA FACS ICC IF IHC WB Biotin Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN1961125 ELISA FACS ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN1972180 ELISA FACS ICC IF IHC WB HRP Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN1974534 ELISA FACS ICC IF IHC WB PE Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN1969947 ELISA FACS ICC IF IHC WB FITC Rabbit IgG AA 24-51 Log in to see Polyclonal
1 ABIN4283301 ELISA FACS ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 Log in to see 4F8
1 ABIN4283306 ELISA FACS ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 Log in to see 4F8
1 ABIN4283303 ELISA FACS ICC IF IHC IHC (p) WB PerCP Mouse IgG1 Log in to see 4F8
1 ABIN4283308 ELISA FACS ICC IF IHC IHC (p) WB DyLight 680 Mouse IgG1 Log in to see 4F8
1 ABIN4283314 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 Log in to see 4F8
1 ABIN4283313 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 Log in to see 4F8
1 ABIN4283315 ELISA FACS ICC IF IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 Log in to see 4F8

General

Antigen B-Cell CLL/lymphoma 10 (BCL10) Antibodies
Reactivity Human, Mouse (Murine)
(300), (93), (48), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(174), (123), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL10 antibody is un-conjugated
(11), (10), (10), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
(232), (137), (115), (109), (96), (88), (59), (33), (26), (13), (3), (3), (2), (2)
Pubmed 3 references available
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Product Details anti-BCL10 Antibody

Target Details BCL10 Application Details Handling References for anti-BCL10 antibody (ABIN2869148) Images
Purpose Purified Mouse Monoclonal Antibody
Characteristics Synonyms: B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, BCL10, CIPER, CLAP
Purification Purified antibody
Immunogen Purified recombinant fragment of human BCL-10 expressed in E. Coli.

Antigen Type: Recombinant Protein
Clone 4F8
Isotype IgG1

Target Details BCL10

Product Details anti-BCL10 Antibody Application Details Handling References for anti-BCL10 antibody (ABIN2869148) Images back to top
Antigen
Alternative Name BCL-10 (BCL10 Antibody Abstract)
Background Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Molecular Weight 26252 Da
Gene ID 8915
NCBI Accession NP_003912
UniProt O95999
Research Area Cancer
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-BCL10 Antibody Target Details BCL10 Handling References for anti-BCL10 antibody (ABIN2869148) Images back to top
Application Notes The suggested dilution is: Western Bloting: = 1:500 - 2000. Immunohistochemistry: = 1:200 - 1000. Immunofluorescence: = 1:200 - 1000.
Restrictions For Research Use only

Handling

Product Details anti-BCL10 Antibody Target Details BCL10 Application Details References for anti-BCL10 antibody (ABIN2869148) Images back to top
Format Liquid
Buffer PBS containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-BCL10 antibody (ABIN2869148)

Product Details anti-BCL10 Antibody Target Details BCL10 Application Details Handling Images back to top
Background publications

Lucas, Yonezumi, Inohara, McAllister-Lucas, Abazeed, Chen, Yamaoka, Seto, Nunez: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, 2001

Wang, Guo, Huang, Ke, Poyet, Manji, Merriam, Glucksmann, DiStefano, Alnemri, Bertin: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, 2001

Willis, Jadayel, Du, Peng, Perry, Abdul-Rauf, Price, Karran, Majekodunmi, Wlodarska, Pan, Crook, Hamoudi, Isaacson, Dyer: "Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types." in: Cell, Vol. 96, Issue 1, pp. 35-45, 1999