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|Application / Reactivity||Sheep (Ovine)||Goat||Cow (Bovine)|
|Flow Cytometry (FACS)||19 Antibodies||10 Antibodies||20 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||2 Antibodies||4 Antibodies|
|Immunohistochemistry (IHC)||1 Antibodies||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies||3 Antibodies||4 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||2 Antibodies||2 Antibodies||3 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies||3 Antibodies||5 Antibodies|
|Antigen||CD8a Molecule (CD8A) Antibodies|
|Reactivity||Cow (Bovine), Goat, Sheep (Ovine) Alternatives|
|Conjugate||This CD8 antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
|7 references available|
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Product Details anti-CD8 AntibodyTarget Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN1449140) Images
|Purification||Affinity Chromatography on Protein G|
Target Details CD8Product Details anti-CD8 Antibody Application Details Handling References for anti-CD8 Antibody (ABIN1449140) Images back to top
|Alternative Name||CD8 (CD8A Antibody Abstract)|
|Background||The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD8 Antibody Target Details CD8 Handling References for anti-CD8 Antibody (ABIN1449140) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD8 Antibody Target Details CD8 Application Details References for anti-CD8 Antibody (ABIN1449140) Images back to top
|Buffer||PBS, 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
References for anti-CD8 Antibody (ABIN1449140)Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling Images back to top
|Product cited in:||
Lynch, Earley, McGee et al.: "Effect of abrupt weaning at housing on leukocyte distribution, functional activity of neutrophils, and acute phase protein response of beef calves." in: BMC veterinary research, Vol. 6, pp. 39, 2010 (PubMed).
Coad, Clifford, Rhodes et al.: "Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses." in: Veterinary research, Vol. 41, Issue 2, pp. 14, 2009 (PubMed).
Sidders, Pirson, Hogarth et al.: "Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex." in: Infection and immunity, Vol. 76, Issue 9, pp. 3932-9, 2008 (PubMed).
Fulton, Portella, Radke: "Dissemination of bovine leukemia virus-infected cells from a newly infected sheep lymph node." in: Journal of virology, Vol. 80, Issue 16, pp. 7873-84, 2006 (PubMed).
Harris, Werling, Koss et al.: "Expression of caveolin by bovine lymphocytes and antigen-presenting cells." in: Immunology, Vol. 105, Issue 2, pp. 190-5, 2002 (PubMed).
Twizere, Kerkhofs, Burny et al.: "Discordance between bovine leukemia virus tax immortalization in vitro and oncogenicity in vivo." in: Journal of virology, Vol. 74, Issue 21, pp. 9895-902, 2000 (PubMed).
Winkler, Doster, Jones: "Persistence and reactivation of bovine herpesvirus 1 in the tonsils of latently infected calves." in: Journal of virology, Vol. 74, Issue 11, pp. 5337-46, 2000 (PubMed).
ImagesProduct Details anti-CD8 Antibody Target Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN1449140) back to top