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|Application / Reactivity||Monkey||Human|
|Flow Cytometry (FACS)||9 Antibodies||825 Antibodies|
|Immunofluorescence (IF)||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||4 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Biochemical Assay (BCA)||3 Antibodies|
|Blocking Antibody (Inhibition)||1 Antibodies|
|Blocking Reagent (BR)||3 Antibodies|
|Co-Stimulation (CoSt)||2 Antibodies|
|Cytotoxicity Test (CyTox)||7 Antibodies|
|ELISA (Detection)||1 Antibodies|
|Enzyme Immunoassay (EIA)||4 Antibodies|
|Fluorescence Microscopy (FM)||1 Antibodies|
|Functional Studies (Func)||5 Antibodies|
|Immunochromatography (IC)||10 Antibodies|
|Immunocytochemistry (ICC)||167 Antibodies|
|Antigen||CD8a Molecule (CD8A) Antibodies|
|Reactivity||Human, Monkey Alternatives|
|Conjugate||This CD8 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
|1 reference available|
|Supplier||Log in to see|
Product Details anti-CD8 AntibodyTarget Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN317156) Images
|Specificity||This antibody recognises the CD8 cell surface antigen, a 30/32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T lymphocytes, and more weakly by NK cells.|
|Characteristics||Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Mouse L cells transfected with human CD8 gene|
Target Details CD8Product Details anti-CD8 Antibody Application Details Handling References for anti-CD8 Antibody (ABIN317156) Images back to top
|Alternative Name||CD8 (CD8A Antibody Abstract)|
|Background||The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD8 Antibody Target Details CD8 Handling References for anti-CD8 Antibody (ABIN317156) Images back to top
Immunohistochemistry on frozen sections. Flow Cytometry: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD8 Antibody Target Details CD8 Application Details References for anti-CD8 Antibody (ABIN317156) Images back to top
|Buffer||Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.
|Expiry Date||12 months|
References for anti-CD8 Antibody (ABIN317156)Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling Images back to top
Walton, Macey, Thornhill, Farthing: "Intra-epithelial subpopulations of T lymphocytes and Langerhans cells in oral lichen planus." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 27, Issue 3, pp. 116-23, 1998