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|Antigen||CD8a Molecule (CD8A) Antibodies|
|Reactivity||Pig (Porcine) Alternatives|
|Conjugate||This CD8 antibody is conjugated to FITC Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (IHC)
|2 references available|
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Product Details anti-CD8 AntibodyTarget Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN135477) Images
The antibody detects: Porcine CD8a, Mr 32-34 kDa
MAb 76-2-11 reacts with the CD8 chain.
|Purification||Ion exchange column|
Target Details CD8Product Details anti-CD8 Antibody Application Details Handling References for anti-CD8 Antibody (ABIN135477) Images back to top
|Alternative Name||CD8a (CD8A Antibody Abstract)|
|Background||Porcine CD8, a type I transmembrane glycoprotein, is expressed as either a CD8 homodimer or a CD8 heterodimer. It is found on most thymocytes, and on the suppressor/cytotoxic subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted T-cell receptors in antigen recognition.|
|Research Area||CD Antigens, Surface Receptors of Immune Cells, Major Histocompatibility Complex (MHC)|
Application DetailsProduct Details anti-CD8 Antibody Target Details CD8 Handling References for anti-CD8 Antibody (ABIN135477) Images back to top
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Cytotoxicity assays, In vivo depletion of CD8+ cells
|Sample Volume||1 mL|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD8 Antibody Target Details CD8 Application Details References for anti-CD8 Antibody (ABIN135477) Images back to top
|Buffer||Product is supplied as 0.5 mg in 1.0 mL of PBS / NaN3.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.
References for anti-CD8 Antibody (ABIN135477)Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling Images back to top
|Product cited in:||
Ferrari, De Angelis, Martelli, Borghetti: "Swine virus-specific cytotoxic cells producing IFNgamma under different conditions of virus antigenic stimulation." in: Veterinary research communications, 2010
Pescovitz, Lunney, Sachs: "Preparation and characterization of monoclonal antibodies reactive with porcine PBL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 133, Issue 1, pp. 368-75, 1984
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