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anti-Turkey CD8 antibody for Flow Cytometry

Recommended CD8 Antibody (supplied by: Log in to see )

Antigen
CD8a Molecule (CD8A) Antibodies
  • BB154331
  • CD8
  • cd8
  • Leu2
  • LOC100136450
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • MAL
  • p32
  • RHACD8-4
  • zgc:136643
Reactivity
Chicken, Turkey
766
404
130
67
28
27
25
20
20
16
15
12
12
11
11
10
10
9
8
7
3
3
2
2
2
2
1
1
1
Host
Mouse
960
391
161
Clonality
Monoclonal
Conjugate
This CD8 antibody is conjugated to Biotin
243
190
121
86
30
30
27
18
18
17
16
15
13
11
10
10
10
9
8
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
1177
282
232
188
136
111
105
81
69
36
33
25
23
17
14
10
7
6
6
6
5
4
4
2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN371439
$ 445.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010476487 ABIN371441 FACS FITC Mouse IgG2b Log in to see 28-02-98 3
0.0010476487 ABIN371443 FACS PE Mouse IgG2b Log in to see 28-02-98 3
0.0010476487 ABIN371440 FACS Cy5 Mouse IgG2b Log in to see 28-02-98 3
0.0010476487 ABIN371442 Func FACS IHC (fro) IP Mouse IgG2b Log in to see 28-02-98
0.0010476487 ABIN2472763 FACS PE Mouse IgG1 Log in to see 11-39 3
0.0010476487 ABIN2472762 FACS FITC Mouse IgG1 Log in to see 11-39 3
0.0010476487 ABIN2472761 FACS IP Mouse IgG1 Log in to see 11-39 3

Top referenced anti-CD8 antibody for Flow Cytometry

Similar anti-CD8 Antibodies

Application / Reactivity Chicken Turkey
Immunoprecipitation (IP) 41 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 56 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 15 Antibodies 1 Antibodies
Functional Studies (Func) 2 Antibodies 1 Antibodies
Flow Cytometry (FACS) 80 Antibodies 8 Antibodies

General

Antigen CD8a Molecule (CD8A) Antibodies
Reactivity Chicken, Turkey
(766), (404), (130), (67), (28), (27), (25), (20), (20), (16), (15), (12), (12), (11), (11), (10), (10), (9), (8), (7), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Host Mouse
(960), (391), (161)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD8 antibody is conjugated to Biotin
(243), (190), (121), (86), (30), (30), (27), (18), (18), (17), (16), (15), (13), (11), (10), (10), (10), (9), (8), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(1177), (282), (232), (188), (136), (111), (105), (81), (69), (36), (33), (25), (23), (17), (14), (10), (7), (6), (6), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CD8 Antibody

Target Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN371439) Images
Characteristics Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
Clone 28-02-98
Isotype IgG2b

Target Details CD8

Product Details anti-CD8 Antibody Application Details Handling References for anti-CD8 Antibody (ABIN371439) Images back to top
Antigen
Alternative Name CD8 (CD8A Antibody Abstract)
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
UniProt Q0R4I4
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD8 Antibody Target Details CD8 Handling References for anti-CD8 Antibody (ABIN371439) Images back to top
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.4)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD8 Antibody Target Details CD8 Application Details References for anti-CD8 Antibody (ABIN371439) Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-CD8 Antibody (ABIN371439)

Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling Images back to top
Background publications

Li, Nestor, Saif, Fan, Luhtala, Vainio: "Cross-reactive anti-chicken CD4 and CD8 monoclonal antibodies suggest polymorphism of the turkey CD8alpha molecule." in: Poultry science, Vol. 78, Issue 11, pp. 1526-31, 1999

Tregaskes, Kong, Paramithiotis, Chen, Ratcliffe, Davison, Young et al.: "Identification and analysis of the expression of CD8 alpha beta and CD8 alpha alpha isoforms in chickens reveals a major TCR-gamma delta CD8 alpha beta subset of intestinal intraepithelial ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 9, pp. 4485-94, 1995

Chan, Chen, Ager, Cooper: "Identification of the avian homologues of mammalian CD4 and CD8 antigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 7, pp. 2133-8, 1988