Browse our anti-Crk (CRK) Antibodies

Full name:
anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) Antibodies (CRK)
On www.antibodies-online.com are 144 V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Antibodies from 22 different suppliers available. Additionally we are shipping Crk Kits (13) and Crk Proteins (10) and many more products for this protein. A total of 186 Crk products are currently listed.
Synonyms:
c-Crk, CG1587, crk, Crk-I, Crk-II, Crk-III, crk2, Crk3, crkII, CrkIII, Crko, D-Crk, dCrk, Dmel\\CG1587, fb34h10, fc05a01, fi19g05, p38, P38C-CRK, v-crk, wu:fb34h10, wu:fc05a01, wu:fc54a04, wu:fi19g05, zgc:100936

Most Popular Reactivities for anti-Crk (CRK) Antibodies

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anti-Rat (Rattus) Crk Antibodies:

anti-Mouse (Murine) Crk Antibodies:

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Top referenced anti-Crk Antibodies

  1. Chicken Monoclonal Crk Primary Antibody for BI, IP - ABIN967702 : Cho, Klemke: Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold. in The Journal of cell biology 2002 (PubMed)
    Show all 7 references for 967702

  2. Human Polyclonal Crk Primary Antibody for EIA - ABIN358272 : Bougnères, Girardin, Weed, Karginov, Olivo-Marin, Parsons, Sansonetti, Van Nhieu: Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. in The Journal of cell biology 2004 (PubMed)
    Show all 5 references for 358272

  3. Human Polyclonal Crk Primary Antibody for DB - ABIN389702 : Sun, Barbieri: Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 389702

  4. Human Monoclonal Crk Primary Antibody for ICC, FACS - ABIN969063 : Watanabe, Tsuda, Tanaka, Ohba, Kawaguchi, Majima, Sawa, Minami: Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation. in Molecular cancer research : MCR 2009 (PubMed)
    Show all 2 references for 969063

  5. Human Polyclonal Crk Primary Antibody for ICC, IF - ABIN442021 : Park, Choi, Choi, Kim, Kang, Jung, Lee, Kim, Freeman, Lee, Gho, Kim: Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. in Proteomics 2013 (PubMed)

More Antibodies against Crk Interaction Partners

Zebrafish V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) interaction partners

  1. The adaptor proteins Crk and Crk-like (Crkl (show CRKL Antibodies)), with which Dock proteins are known to interact physically, are also required for myoblast fusion.

Human V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) interaction partners

  1. Study investigated structures and thermodynamics of the interactions mediated by N-terminal Src homology 3 domain of CrkII and proline-rich motifs (PRMs) of cAbl kinase, highlight the role of interfacial water molecules and the conformational entropy in the SH3:PRM interactions

  2. CrkII mediates IGF-1 (show IGF1 Antibodies) signaling and further balances pancreatic ductal adenocarcinoma biological behaviors via Erk1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) pathway

  3. In individuals with class I 17p13.3 microduplications including CRK, we recommend biochemical evaluation of the growth hormone (show GH1 PLURAL_@26348@) axis. Providers caring for these patients should be aware of their possible risk for the development of central precocious puberty.

  4. Crk Tyr251 phosphorylation regulate invasive cell phenotypes in glioblastoma.

  5. CsA (show ERCC8 Antibodies) and FK506 might interfere with selected effector T cell functions via a CrkII-, but not CrkI-dependent mechanisms.

  6. Studied the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC).

  7. in human c-CrkII, movement at position 239 and strain at position 272 are not tolerated because the beta-branched residues Ile239 and Val272 restrain the backbone mobility and thus destabilize the cis (show CISH Antibodies) Pro238 form.

  8. Data indicate the role of tyrosine phosphorylation in regulating modular domain utilization in v-crk sarcoma virus CT10 oncogene homolog (avian) protein (Crk).

  9. evidence uncovered essential roles of CRK in invasive bladder cancer through the hepatocyte growth factor (show HGF Antibodies)/c-Met/CRK feedback loop for epithelial-mesenchymal transition induction

  10. In this review, we describe the structure and function of the different Crk proteins.

Mouse (Murine) V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) interaction partners

  1. the data suggest that CCRK (show CDK20 Antibodies) positively regulates the kinetics by which ciliary proteins such as Smoothened and Gli2 (show GLI2 Antibodies) are imported into the cilium, and that the efficiency of ciliary recruitment allows for potent responses to Hedgehog (show SHH Antibodies) signaling over long time periods.

  2. results suggest that Crk and CrkL (show CRKL Antibodies) play essential overlapping roles in fibroblast growth.

  3. both Crk and CrkL are required for the acquisition of cellular transformation by v-fos, whereas Crk plays a more prominent role than CrkL in v-ras-induced transformation.

  4. results support a model in which Dok1 (show DOK1 Antibodies) phosphorylation normally suppresses localized Ras pathway activity in Crk-transformed cells via recruitment and/or activation of RasGAP (show RASA1 Antibodies)

  5. Differential migration of CRK/CRKL (show CRKL Antibodies)-deficient T cells resulted in efficient graft-versus-leukemia responses with minimal graft-versus-host disease in mice.

  6. Crk1 (show MAPK14 Antibodies)/2 and CrkL (show CRKL Antibodies) are physically linked, functionally complement each other during podocyte foot process spreading, and together are required for developing typical foot process architecture.

  7. Data suggest that interactions between Crk (proto-oncogene (show RAB1A Antibodies) proteins c-crk) and Sos1 (Son of Sevenless homolog 1 (show SOS1 Antibodies)) involve electrostatic interactions at binding sites.

  8. Results suggest that Crk and CrkL (show CRKL Antibodies) have critical roles in cell structure and motility by maintaining cytoskeletal integrity.

  9. The v-Crk-myosin-1c interaction, which modulates membrane dynamics by regulating Rac1 activity, is crucial for cell adhesion and spreading.

  10. The authors cloned SH2 (show MYO15 Antibodies) domain-containing proteins they named GRBs (for growth factor receptor (show RYK Antibodies)-bound). They identified GRB-3 as having 77% identity at the protein level and 80% similarity at the DNA level to v-crk.

Crk (CRK) Antigen Profile

Antigen Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Alternative names and synonyms associated with Crk (CRK)

  • CG1587 gene product from transcript CG1587-RD (Crk) antibody
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (crk) antibody
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (CRK) antibody
  • v-crk avian sarcoma virus CT10 oncogene homolog (CRK) antibody
  • v-crk avian sarcoma virus CT10 oncogene homolog (Crk) antibody
  • v-crk avian sarcoma virus CT10 oncogene homolog (crk) antibody
  • v-crk sarcoma virus CT10 oncogene homolog (CRK) antibody
  • v-crk sarcoma virus CT10 oncogene homolog (avian) (Crk) antibody
  • c-Crk antibody
  • CG1587 antibody
  • crk antibody
  • Crk-I antibody
  • Crk-II antibody
  • Crk-III antibody
  • crk2 antibody
  • Crk3 antibody
  • crkII antibody
  • CrkIII antibody
  • Crko antibody
  • D-Crk antibody
  • dCrk antibody
  • Dmel\\CG1587 antibody
  • fb34h10 antibody
  • fc05a01 antibody
  • fi19g05 antibody
  • p38 antibody
  • P38C-CRK antibody
  • v-crk antibody
  • wu:fb34h10 antibody
  • wu:fc05a01 antibody
  • wu:fc54a04 antibody
  • wu:fi19g05 antibody
  • zgc:100936 antibody

Protein level used designations for CRK

CG1587-PA , CG1587-PB , CG1587-PC , CG1587-PD , CG1587-PE , CG1587-PF , Crk-PA , Crk-PB , Crk-PC , Crk-PD , Crk-PE , Crk-PF , adapter molecule crk , v-crk sarcoma virus CT10 oncogene homolog (avian) , proto-oncogene c-Crk , avian sarcoma virus CT10 (v-crk) oncogene homolog , p38 , proto-oncogene C-crk , v-crk sarcoma virus CT10 oncogene homolog , SH2/SH3 adaptor Crk2 , SH2/SH3 adaptor crk , CT-10 related kinase 3 , proto-oncogene c-crk , v-crk sarcoma virus CT10 oncogene-like protein

GENE ID SPECIES
43775 Drosophila melanogaster
445234 Danio rerio
512841 Bos taurus
747142 Pan troglodytes
1398 Homo sapiens
54245 Rattus norvegicus
398951 Xenopus laevis
417553 Gallus gallus
12928 Mus musculus
100684309 Canis lupus familiaris
100192444 Sus scrofa
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