Browse our Major Histocompatibility Complex, Class II, DP alpha 1 Proteins (HLA-DPA1)

Full name:
Major Histocompatibility Complex, Class II, DP alpha 1 Proteins (HLA-DPA1)
On www.antibodies-online.com are 3 Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) Proteins from 2 different suppliers available. Additionally we are shipping Major Histocompatibility Complex, Class II, DP alpha 1 Antibodies (53) and Major Histocompatibility Complex, Class II, DP alpha 1 Kits (1) and many more products for this protein. A total of 63 Major Histocompatibility Complex, Class II, DP alpha 1 products are currently listed.
Synonyms:
DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1
list all proteins Gene Name GeneID UniProt
HLA-DPA1 3113 P20036

Show all synonyms

Major Histocompatibility Complex, Class II, DP alpha 1 Proteins (HLA-DPA1) by Origin

Select your origin of interest

More Proteins for Major Histocompatibility Complex, Class II, DP alpha 1 Interaction Partners

Human Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) interaction partners

  1. The HLA-B*42, HLA-C*17, HLA-DPA1*03, and HLA-DPB1 (show HLA-DPB1 Proteins)*105 genotypes were associated with allergic asthma and the HLA-B*48 genotype with the nonallergic phenotype. The presence of the haplotype HLA-DPA1*03 DQA*05 was associated with allergic asthma, and the presence of HLA-DPA1*03 and the absence of HLA-DQA*05 with nonallergic asthma.

  2. Single-nucleotide polymorphism in HLA-DPA1 gene is associated with sclerotic graft-versus-host disease.

  3. Single-nucleotide polymorphism in HLA-DP (show HLA-DPB1 Proteins) is associated with cervical cancer susceptibility.

  4. rs3077 in HLA-DPA1 is a significantly associated SNP associated with chronic hepatitis B virus infection and viral clearance.

  5. This resource provides population estimates of the frequencies of HLA alleles at these eight loci in the three population groups, particularly for HLA-DPA1 and HLA-DPB1 (show HLA-DPB1 Proteins) that were not assayed in HapMap.

  6. DPA1*02:01- DPB1 (show HLA-DPB1 Proteins)*14:01 and DPA1*02:01- DPB1 (show HLA-DPB1 Proteins)*17:01 haplotypes provide considerable protection effect against Posner-Schlossman syndrome.

  7. HLA-DP (show HLA-DPB1 Proteins) gene polymorphisms are strongly associated with chronic hepatitis B virus infection.

  8. The study suggests that HLA-DPA1/B1 loci are candidate susceptibility regions that have some marker single nucleotide polymorphisms for both chronic hepatitis C virus infection and F protein generation in the Han Chinese population.

  9. Single nucleotide polymorphisms rs3077 and rs9277378 in HLA-DPA1 and HLA-DPB1 (show HLA-DPB1 Proteins) are significantly associated with protective effects against chronic hepatitis B.

  10. HLA-DPA1 and DPB1 (show HLA-DPB1 Proteins) allele frequencies and haplotypes of the population of Guadeloupe were most similar to African populations, with characteristic alleles and haplotypes that bespeaks the admixture with other ethnicities.

Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) Protein Profile

Protein Summary

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Alternative names and synonyms associated with Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1)

  • major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1)
  • DP(W3) protein
  • DP(W4) protein
  • HLA-DP1A protein
  • HLADP protein
  • HLASB protein
  • PLT1 protein

Protein level used designations for HLA-DPA1

HLA class II histocompatibility antigen, DP alpha 1 chain , HLA-SB alpha chain , MHC class II DP3-alpha , MHC class II HLA-DPA1 antigen , MHC class II antigen , Primed lymphocyte test-1

GENE ID SPECIES
3113 Homo sapiens
Selected quality suppliers for Major Histocompatibility Complex, Class II, DP alpha 1 Proteins (HLA-DPA1)
Did you look for something else?