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|Antigen||Interleukin 17A (IL17A) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This IL17A antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IL17A AntibodyTarget Details IL17A Application Details Handling Images
|Specificity||This antibody reacts to Il-17.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||IL-17 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-17A.|
Target Details IL17AProduct Details anti-IL17A Antibody Application Details Handling Images back to top
|Alternative Name||Interleukin-17A (IL17A) (IL17A Antibody Abstract)|
|Background||Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17|
|Research Area||Cancer, Cytokines, Immunology, Inflammation, Receptors, Virology|
Application DetailsProduct Details anti-IL17A Antibody Target Details IL17A Handling Images back to top
ELISA. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL17A Antibody Target Details IL17A Application Details Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store the antibody undiluted at 2-8 °C.|