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anti-Rat (Rattus) IL17A antibody for Enzyme Immunoassay

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Reactivity
Mouse (Murine), Rat (Rattus)
306
173
53
10
5
5
1
Host
Rabbit
200
128
96
42
8
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
63
31
26
18
17
9
7
6
6
6
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
251
249
138
42
39
27
24
22
19
14
11
10
9
9
9
8
7
6
5
4
4
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN401113
$ 500.50
Plus shipping costs $45.00

Top referenced anti-IL17A antibody for Enzyme Immunoassay

Similar anti-IL17A Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Confocal Microscopy (CM) 2 Antibodies 2 Antibodies
ELISA 19 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 12 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Intracellular Staining (ICS) 9 Antibodies
Neutralization (Neut) 1 Antibodies
Radioimmunoassay (RIA) 1 Antibodies
Western Blotting (WB) 26 Antibodies
Biochemical Assay (BCA) 1 Antibodies
Blocking Antibody (Inhibition) 3 Antibodies

General

Antigen Interleukin 17A (IL17A) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(306), (173), (53), (10), (5), (5), (1)
Host Rabbit
(200), (128), (96), (42), (8), (3), (1)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(63), (31), (26), (18), (17), (9), (7), (6), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(251), (249), (138), (42), (39), (27), (24), (22), (19), (14), (11), (10), (9), (9), (9), (8), (7), (6), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN401113) Images
Purification Ig Fraction
Immunogen Full-length recombinant Rat IL17-A protein . Genename: IL17A
Isotype IgG

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling References for anti-IL17A Antibody (ABIN401113) Images back to top
Antigen
Alternative Name Interleukin-17A (IL17A) (IL17A Antibody Abstract)
Background Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyteassociated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58 % identity between the amino acid sequence of Human and Rat IL-17A.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
Gene ID 10116
UniProt Q61453
Research Area Cytokines, Receptors, Inflammation, Immunology, Virology, Cancer
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling References for anti-IL17A Antibody (ABIN401113) Images back to top
Application Notes ELISA: 1/20000 - 1/100000. Western Blot: 1/500 - 1/2000. Neutralization: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details References for anti-IL17A Antibody (ABIN401113) Images back to top
Reconstitution Restore with 0.1 mL of deionized water (or equivalent).
Concentration 1.0 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 without preservatives and stabilizers. The Endotoxin content is estimated to be less than 10 pg/mL by the LAL method.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IL17A Antibody (ABIN401113)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Background publications

Kennedy, Rossi, Zurawski, Vega, Kastelein, Wagner, Hannum, Zlotnik: "Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4-CD8-T cells." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 16, Issue 8, pp. 611-7, 1997

Yao, Timour, Painter, Fanslow, Spriggs: "Complete nucleotide sequence of the mouse CTLA8 gene." in: Gene, Vol. 168, Issue 2, pp. 223-5, 1996

Rouvier, Luciani, Mattéi, Denizot, Golstein: "CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5445-56, 1993

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN401113) back to top
Supplier Images
 image for anti-IL17A antibody (Interleukin 17A) (ABIN401113) anti-Interleukin 17A (IL17A) antibody
 image for anti-IL17A antibody (Interleukin 17A) (ABIN401113) anti-Interleukin 17A (IL17A) antibody (Image 2)