|Antigen||Luteinizing Hormone beta Polypeptide (LHB) Antibodies|
|Reactivity||Pig (Porcine) Alternatives|
|Conjugate||This LHB antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
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Product Details anti-LHB AntibodyTarget Details LHB Application Details Handling Images
|Specificity||This antibody is specific for porcine luteinizing hormone and does not react with GH, TSH, LH alpha or prolactin. Minimal reactivity has been observed with FSH.|
|Purification||Ammonium sulphate precipitation|
|Immunogen||Porcine luteinizing hormone|
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|Alternative Name||Luteinizing Hormone beta (LSH-Beta) (LHB Antibody Abstract)|
|Background||Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.|
|Pathways||Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process|
Application DetailsProduct Details anti-LHB Antibody Target Details LHB Handling Images back to top
Immunohistochemistry on frozen sections: 1/200 - 1/500. Western Blot: 1/300 - 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LHB Antibody Target Details LHB Application Details Images back to top
|Reconstitution||Reconstitute with 50 μL sterile distilled water. For long term storage the addition of a preservative is recommended.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage Comment||Prior to and following reconstitution store the antibody at -20 °C.|