Browse our Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2)

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Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2)
On www.antibodies-online.com are 11 Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) Proteins from 6 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 2, Group C, Member 2 Antibodies (252) and Nuclear Receptor Subfamily 2, Group C, Member 2 Kits (8) and many more products for this protein. A total of 288 Nuclear Receptor Subfamily 2, Group C, Member 2 products are currently listed.
Synonyms:
B430101B05, C87327, gb:dq017625, hTAK1, im:6911408, mKIAA4145, TAK1, TR2R1, Tr4
list all proteins Gene Name GeneID UniProt
NR2C2 313121 P0C8E4
NR2C2 26409 Q62073
NR2C2 7182 P49116

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Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2) by Origin

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More Proteins for Nuclear Receptor Subfamily 2, Group C, Member 2 Interaction Partners

Mouse (Murine) Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) interaction partners

  1. Transforming growth factor-beta activated kinase 1 (TAK1 (show MAP3K7 Proteins)) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (show FAM126A Proteins)) development.

  2. TAK1 regulates Nrf2 (show NFE2L2 Proteins) through modulation of Keap-p62/SQSTM1 (show SQSTM1 Proteins) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  3. CNS-specific Tak1 deletion prevented ER-stress-induced hypothalamic leptin (show LEP Proteins) resistance and hyperphagic obesity under a high-fat diet (HFD). Thus, TAK1 is a crucial regulator of ER stress in vivo, which could be a target for alleviation of ER stress and its associated disease conditions.

  4. SIRT7 (show SIRT7 PLURAL_@36464@) inhibits TR4 degradation by deacetylation of DDB1 (show DDB1 PLURAL_@36464@).

  5. this study shows that TAK1 negatively regulates lipopolysaccharide-induced cytokine secretion in myeloid cells by inhibiting MEKK3 (show MAP3K3 Proteins) activities

  6. TR4 binds GR to play an important role in glucocorticoid-directed corticotroph tumor POMC (show POMC Proteins) regulation in addition to modulating glucocorticoid actions on other GR targets.

  7. Mekk1 (show MAP2K1 Proteins) (encoded by Map3k1 (show MAP3K1 Proteins)) signaling activates Mapks to regulate Cdkn1b (show CDKN1B Proteins) (encoding p27(Kip1 (show CDKN1B Proteins))) expression and p27(Kip1 (show CDKN1B Proteins))-dependent proliferative expansion in response to antigen.

  8. TRADD (show TRADD Proteins) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1/p38 MAPK (show MAPK14 Proteins) but not AKT (show AKT1 Proteins) phosphorylation

  9. The present study demonstrates that TIPE2 (show TNFAIP8L2 Proteins) acts as a novel negative regulator of inflammatory and immune responses through TAK1 signaling.

  10. this study demonstrates a pivotal role of TAK1 in dendritic cells in controlling trichloroethylene-induced contact hypersensitivity response and suggests that targeting TAK1 function in DCs may be a viable approach to preventing and treating TCE-related occupational health hazards

Human Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) interaction partners

  1. High TAK1 (show MAP3K7 Proteins) expression is associated with the progression of hepatocellular carcinoma.

  2. Here, we report that Pseudomonas aeruginosa ExoY inhibits proinflammatory cytokine production through suppressing the activation of TAK1 (show MAP3K7 Proteins) as well as downstream NF-kappaB (show NFKB1 Proteins) and mitogen-activated protein (MAP) kinases.

  3. SIRT7 (show SIRT7 PLURAL_@36464@) inhibits TR4 degradation by deacetylation of DDB1 (show DDB1 PLURAL_@36464@).

  4. TR4 binds GR to play an important role in glucocorticoid-directed corticotroph tumor POMC (show POMC Proteins) regulation in addition to modulating glucocorticoid actions on other GR targets.

  5. this study shows that TAP1 (show TAP1 Proteins) plays a novel role in the negative regulation of virus-triggered NF-kappaB (show NFKB1 Proteins) signaling and the innate immune response by targeting the TAK1 (show MAP3K7 Proteins) complex

  6. TAK1 (show MAP3K7 Proteins)/TAB1 (show TAB1 Proteins) expression in non-small cell lung carcinoma tissue is significantly increased and closely associated with patient clinical prognosis.

  7. miR (show MLXIP Proteins)-203 represses NF-kappaB (show NFKB1 Proteins) signaling via targeting TAK1 (show MAP3K7 Proteins) and PI3KCA and miR (show MLXIP Proteins)-203 overexpression may contribute to the COPD (show ARCN1 Proteins) initiation.

  8. DK1 inhibits the formation of the TAK1 (show MAP3K7 Proteins)-TAB2 (show TAB2 Proteins)-TRAF6 (show TRAF6 Proteins) complex and leads to the inhibition of TRAF6 (show TRAF6 Proteins) ubiquitination.

  9. IFIT5 promotes SeV-induced IKK (show CHUK Proteins) phosphorylation and NF-kappaB (show NFKB1 Proteins) activation by regulating the recruitment of IKK (show CHUK Proteins) to TAK1 (show MAP3K7 Proteins).

  10. USP18 (show USP18 Proteins) negatively regulates NF-kappaB (show NFKB1 Proteins) signaling by targeting TAK1 (show MAP3K7 Proteins) and NEMO (show IKBKG Proteins) for deubiquitination through distinct mechanisms.

Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) Protein Profile

Protein Summary

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996

Alternative names and synonyms associated with Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2)

  • mitogen activated protein kinase kinase kinase 7 (Map3k7)
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7)
  • nuclear receptor subfamily 2, group C, member 2 (NR2C2)
  • nuclear receptor subfamily 2, group C, member 2 (Nr2c2)
  • nuclear receptor subfamily 2, group C, member 2 (nr2c2)
  • B430101B05 protein
  • C87327 protein
  • gb:dq017625 protein
  • hTAK1 protein
  • im:6911408 protein
  • mKIAA4145 protein
  • TAK1 protein
  • TR2R1 protein
  • Tr4 protein

Protein level used designations for NR2C2

TGF-beta activated kinase 1 , mitogen-activated protein kinase kinase kinase 7 , TGF-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , Nuclear hormone receptor TR4 , TR4 nuclear hormone receptor , nuclear receptor subfamily 2 group C member 2 , orphan nuclear receptor TAK1 , orphan nuclear receptor TR4 , testicular nuclear receptor 4 , testicular receptor 4 , nuclear receptor subfamily 2, group H, member 2 , orphan receptor, TR4 , TR4 orphan receptor , TR4-NS orphan receptor , orphan receptor TR4

GENE ID SPECIES
313121 Rattus norvegicus
26409 Mus musculus
7182 Homo sapiens
484641 Canis lupus familiaris
505531 Bos taurus
22026 Mus musculus
50659 Rattus norvegicus
569321 Danio rerio
395253 Gallus gallus
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