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anti-Mouse (Murine) TAX1BP1 Antibodies:
anti-Human TAX1BP1 Antibodies:
anti-Rat (Rattus) TAX1BP1 Antibodies:
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Human Polyclonal TAX1BP1 Primary Antibody for ICC, IF - ABIN4357936
Newman, Scholefield, Kemp, Newman, McIver, Kamal, Wilkinson: TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. in PLoS ONE 2012
Show all 2 references for ABIN4357936
The kinase IKKalpha (show CHUK Antibodies) inhibits activation of the transcription factor NF-kappaB (show NFKB1 Antibodies) by phosphorylating the regulatory molecule TAX1BP1.
The induction of antibodies to an AQP4 (show AQP4 Antibodies) epitope in mice immunized with the TAX1BP1-derived peptide suggests that a latent HTLV-1 infection could lead to TAX1BP1 antigen presentation and the production of anti-AQP4 (show AQP4 Antibodies) antibodies in human neuromyelitis optica.
Antibiotics-induced 'germ free' status or the additional MyD88 (show MYD88 Antibodies) deficiency significantly ameliorated TAX1BP1-KO mice's inflammatory lesions
ABIN1 (show TNIP1 Antibodies) requires its ubiquitin binding domain and cooperates with TAX1BP1 and A20 (show TNFAIP3 Antibodies) to restrict antiviral signaling.
results demonstrate TBK1 (show TBK1 Antibodies)-IKKi (show IKBKE Antibodies) to be novel substrates for A20 (show TNFAIP3 Antibodies) and further identify a novel mechanism whereby A20 (show TNFAIP3 Antibodies) and TAX1BP1 restrict antiviral signaling by disrupting a TRAF3 (show TRAF3 Antibodies)-TBK1 (show TBK1 Antibodies)-IKKi (show IKBKE Antibodies) signaling complex
TAX1BP1 is pivotal for the termination of NF-kappaB (show NFKB1 Antibodies) and JNK (show MAPK8 Antibodies) signaling by functioning as an essential regulator of A20 (show TNFAIP3 Antibodies).
TAX1BP1 is an essential adaptor for linking A20 (show TNFAIP3 Antibodies) to TRAF6 (show TRAF6 Antibodies) and other factors in order to influence NF-B activation.
These results reveal the molecular mechanism of TIP-1 (show TAX1BP3 Antibodies) as an antagonist in PDZ domain (show INADL Antibodies) signaling.
TAX1BP1 downregulation by EBV-miR (show MLXIP Antibodies)-BART15-3p enhances chemosensitivity of gastric cancer cells to 5-fluorouracil.
we demonstrate that myosin VI (show MYO6 Antibodies) and TAX1BP1 are recruited to ubiquitylated Salmonella and play a key role in xenophagy
A protein construct corresponding to the SKICH domain plus the linker region was expressed, purified and crystallized for TAX1BP1.
RNF11 (show RNF11 Antibodies) functions together with TAX1BP1 to restrict antiviral signaling and IFN-beta (show IFNB1 Antibodies) production.
Autophagy of Tax1bp1/Ndp52 (show CALCOCO2 Antibodies) promotes non-canonical NF-kappaB (show NFKB1 Antibodies) signalling.
Allele frequencies of three Alu insertions that are located in MEF2C (show MEF2C Antibodies) (two of them) and TAX1BP1 genes significantly differ between cohorts of healthy donors and ALL(acute lymphoblastic leukemia) patients.
In a link with T cell leukemia virus-1-associated myelopathy/tropical spastic paraparesis, an alphabeta T cell receptor recognizes a self peptide from neuronal protein (show LRCH1 Antibodies) HuD (show ELAVL4 Antibodies) in context of histocompatibility antigen HLA-A2.
There is evidence of the association between the TAX1BP1 polymorphism and oral cavity cancer but there are no differences in the distribution of the polymorphism among patients with head and neck cancer and individuals without history of neoplasm.
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Tax1 (human T-cell leukemia virus type I) binding protein 1
, tax1-binding protein 1 homolog B
, Tax1 binding protein 1
, muscle-derived protein 62
, TRAF6-binding protein homolog
, tax1-binding protein 1 homolog
, TRAF6-binding protein
, tax1-binding protein 1
, liver regeneration-related protein 2
, liver regeneration-related protein LRRG004