TAX1BP1 antibody

Catalog No. ABIN7259536

Product Details anti-TAX1BP1 Antibody

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAX1BP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TAX1BP1 (NP_006015.4).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TAX1BP1

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Alternative Name: TAX1BP1 (TAX1BP1 Products)

Synonyms: CALCOCO3 antibody, T6BP antibody, TXBP151 antibody, 1200003J11Rik antibody, 1700069J21Rik antibody, AA930106 antibody, D6Ertd404e antibody, D6Ertd772e antibody, T6bp antibody, tax1bp1 antibody, zgc:73219 antibody, zgc:77129 antibody, wu:fc20c12 antibody, wu:fc56e11 antibody, MDP62 antibody, MGC132101 antibody, TAX1BP1 antibody, si:ch211-204j16.2 antibody, Tax1 binding protein 1 antibody, Tax1 (human T cell leukemia virus type I) binding protein 1 antibody, Tax1 (human T-cell leukemia virus type I) binding protein 1b antibody, Tax1 binding protein 1 S homeolog antibody, Tax1 (human T-cell leukemia virus type I) binding protein 1 antibody, Tax1 (human T-cell leukemia virus type I) binding protein 1a antibody, Tax1 binding protein 1 L homeolog antibody, TAX1BP1 antibody, Tax1bp1 antibody, tax1bp1b antibody, tax1bp1.S antibody, tax1bp1a antibody, tax1bp1.L antibody

Background: This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID: 8887

UniProt: Q86VP1

Pathways: TLR Signaling