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Browse our Solute Carrier Family 30 (Zinc Transporter), Member 3 Proteins (Slc30a3)

Full name:
Solute Carrier Family 30 (Zinc Transporter), Member 3 Proteins (Slc30a3)
On www.antibodies-online.com are 4 Solute Carrier Family 30 (Zinc Transporter), Member 3 (Slc30a3) Proteins from 3 different suppliers available. Additionally we are shipping Solute Carrier Family 30 (Zinc Transporter), Member 3 Antibodies (35) and Solute Carrier Family 30 (Zinc Transporter), Member 3 Kits (15) and many more products for this protein. A total of 57 Solute Carrier Family 30 (Zinc Transporter), Member 3 products are currently listed.
Synonyms:
pp12488, slc30a3, T32F6.21, T32F6_21, zinc transporter 3 precursor, znt-2, znt2, Znt3
list all proteins Gene Name GeneID UniProt
Rat Slc30a3 Slc30a3 366568 Q6QIX3
Slc30a3 7781 Q99726
Mouse Slc30a3 Slc30a3 22784 P97441

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Solute Carrier Family 30 (Zinc Transporter), Member 3 Proteins (Slc30a3) by Origin

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More Proteins for Solute Carrier Family 30 (Zinc Transporter), Member 3 Interaction Partners

Human Solute Carrier Family 30 (Zinc Transporter), Member 3 (Slc30a3) interaction partners

  1. ZNT3 and ZNT8 (show SLC30A8 Proteins) (known to regulate insulin (show INS Proteins) secretion) have opposite effects on insulin (show INS Proteins) synthesis and secretion possibly by a transcriptional co-regulation since mRNA expression of ZNT3 was inversely correlated to ZNT8 (show SLC30A8 Proteins) and ZNT3 over-expression reduced insulin (show INS Proteins) synthesis and secretion.

  2. An association was found between reduced ZnT3 in the prefrontal cortex and cognitive impairment in patients with either dementia with Lewy bodies or Parkinson's disease dementia.

  3. SNPs in SLC30A3 show a gender-specific association with schizophrenia in an East UK cohort.

  4. The results of this study suggested that ZnT3 protein levels are decreased in the spinal cords of sporadic ALS patients.

  5. AIDL cells exhibited a lower expression of zinc transporter 1 (ZnT1) and higher expression of ZnT3 than LNCaP cells.

  6. Data show that ZNT3 is extensively present in the Abeta (show APP Proteins)-positive plaques in the cortex of human AD brains.

  7. SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

Mouse (Murine) Solute Carrier Family 30 (Zinc Transporter), Member 3 (Slc30a3) interaction partners

  1. ZnT3 null mice lack the transporter responsible for stocking synaptic vesicles, although they do have a zinc veneer, albeit diminished compared to wild-type animals.

  2. Dietary or ZnT3-dependent Zn(2+) stores, and intracellular Zn(2+) release from rhodopsin recycling are suggested to be involved in light-induced retinal degeneration.

  3. Fundamental changes occur in the expression of proteins and genes important in neurotransmission and are different in the absence of vesicular zinc in ZnT3-deficient knockout mice.

  4. This study demonistrated that zinc transporter-3 regulate the Zinc in brain.

  5. Zinc transporters of the Slc30a/ZnT and Slc39a/Zip families play crucial roles in cell functions, mediating zinc influx to and efflux from the lumen of the secretory pathway, constitutively or in a cell-specific manner. (Review)

  6. Deprivation of oxygen and glucose-SD produced large FluoZin-3 increases that propagated with the event, and signals were abolished in tissues from ZnT3 knockout animals lacking synaptic Zn(2+)

  7. ZnT3 is important for zinc homeostasis modulating presynaptic MAPK (show MAPK1 Proteins) signaling and is required for hippocampus-dependent memory

  8. Data suggest that expression of zinc homeostatic proteins such as ZnT1 and 3, and metallothioneins 1 and 2, is regulated by crosstalk between synaptic and intracellular pools of Zn(2+).

  9. The results of this study suggested that ZnT3 protein is involved in the Abeta (show APP Proteins) aggregation in the cerebellum of the AbetaPP/PS1 (show PSEN1 Proteins) mouse.

  10. Age-dependent loss of transsynaptic Zn(2+) movement leads to cognitive loss, and since extracellular beta-amyloid is aggregated by this pool of Zn(2+), the genetic ablation of ZnT3 may represent a phenocopy for the synaptic and memory deficits of AD.

Solute Carrier Family 30 (Zinc Transporter), Member 3 (Slc30a3) Protein Profile

Protein Summary

Involved in accumulation of zinc in synaptic vesicles.

Alternative names and synonyms associated with Solute Carrier Family 30 (Zinc Transporter), Member 3 (Slc30a3)

  • solute carrier family 30 (zinc transporter), member 2 (slc30a2)
  • solute carrier family 30 (zinc transporter), member 3 (SLC30A3)
  • solute carrier family 30 (zinc transporter), member 3 (Slc30a3)
  • zinc transporter 3 (ZIP3)
  • pp12488 protein
  • slc30a3 protein
  • T32F6.21 protein
  • T32F6_21 protein
  • zinc transporter 3 precursor protein
  • znt-2 protein
  • znt2 protein
  • Znt3 protein

Protein level used designations for Slc30a3

solute carrier family 30 (zinc transporter), member 3 , solute carrier family 30 member 3 , solute carrier family 30 protein , zinc transporter 3 , zinc transporter ZnT-3 , znT-3

GENE ID SPECIES
448552 Xenopus (Silurana) tropicalis
470339 Pan troglodytes
699572 Macaca mulatta
366568 Rattus norvegicus
7781 Homo sapiens
22784 Mus musculus
512803 Bos taurus
475700 Canis lupus familiaris
100169931 Sus scrofa
817787 Arabidopsis thaliana
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