anti-Human CTNNB1 antibody for Immunocytochemistry

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • Jup
  • LOC100217813
  • CTNNB1
  • CTNNB
  • Bfc
  • Catnb
  • Mesc
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • ctnnb1
  • CHBCAT
  • MRD19
  • armadillo
  • beta-catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin (cadherin associated protein), beta 1
  • catenin (cadherin-associated protein), beta 1
  • CTNNB1
  • LOC100217813
  • Ctnnb1
  • ctnnb1
  • ctnnb1-a
  • ctnnb1-b
Reactivity
Human
493
224
198
63
53
41
26
25
21
21
15
15
15
10
9
9
3
1
1
1
1
1
1
Host
Mouse
310
193
9
2
Clonality
Monoclonal
Conjugate
This CTNNB1 antibody is un-conjugated
14
11
8
8
7
6
4
4
4
4
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
443
153
127
124
112
111
70
30
16
13
8
8
4
4
3
3
2
2
1
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Catalog No. ABIN969072
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
26.428953 ABIN457419 ICC FACS IP WB Mouse IgG1 C-Term, AA 441-448 Log in to see EM-22 3
1 ABIN5518651 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 1-19, N-Term Log in to see Polyclonal 3
1 ABIN2869463 ELISA FACS ICC IHC WB Mouse IgG1 Log in to see 4D5 3
1 ABIN3044344 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 764-781, C-Term Log in to see Polyclonal 3
1 ABIN574434 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see EM-22
1 ABIN211079 ICC IP WB Rabbit IgG AA 29-49 Log in to see Polyclonal
1 ABIN364501 ICC IHC (p) IP WB Mouse IgG AA 758-771, C-Term Log in to see
1 ABIN2619644 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 1-19 Log in to see Polyclonal
1 ABIN215673 ICC IP ELISA WB Mouse IgG2b Log in to see
1 ABIN215671 ICC IHC (p) ELISA WB Mouse IgG1 AA 35-50 Log in to see
1 ABIN3020927 ICC IP IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1858529 ICC IHC IP WB Rabbit IgG AA 439-675 Log in to see Polyclonal
1 ABIN200357 ICC IP IHC WB Mouse IgG AA 758-771, C-Term Log in to see
1 ABIN600589 ICC IHC ELISA WB Mouse IgG1, kappa AA 36-44 Log in to see
1 ABIN322660 ICC IF WB Mouse IgG1 Log in to see
1 ABIN227275 ICC IHC (p) IP ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1723571 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see EM-22
1 ABIN600588 ICC IHC ELISA WB Mouse IgG1, kappa AA 36-44 Log in to see
1 ABIN604612 ICC ELISA WB Mouse IgG1 Log in to see
1 ABIN1964799 ELISA ICC IF IHC WB APC Rabbit IgG AA 653-681 Log in to see Polyclonal

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Reactivity Human
(493), (224), (198), (63), (53), (41), (26), (25), (21), (21), (15), (15), (15), (10), (9), (9), (3), (1), (1), (1), (1), (1), (1)
Host Mouse
(310), (193), (9), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CTNNB1 antibody is un-conjugated
(14), (11), (8), (8), (7), (6), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(443), (153), (127), (124), (112), (111), (70), (30), (16), (13), (8), (8), (4), (4), (3), (3), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) Images
Purification Ascites
Immunogen Purified recombinant fragment of human CTNNB1 expressed in E. Coli.
Clone 4D5
Isotype IgG1

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) Images back to top
Antigen
Alternative Name CTNNB1 (CTNNB1 Antibody Abstract)
Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
Molecular Weight 85 kDa
Gene ID 1499
HGNC 1499
Pathways WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 antibody (ABIN969072) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 antibody (ABIN969072) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-CTNNB1 antibody (ABIN969072)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Product cited in:

Bougatef, Ouerhani, Moussa, Kourda, Coulet, Colas, Lahely, Najjar, Ben Jilani, Benammar-Elgaaied, Soubrier, Marrakchi: "Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer." in: Cancer genetics and cytogenetics, Vol. 187, Issue 1, pp. 12-8, 2008

Guo, Liu, Yang, Zhang, Yao: "Relation among p130Cas, E-cadherin and beta-catenin expression, clinicopathologic significance and prognosis in human hepatocellular carcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 5, pp. 490-6, 2008

Background publications

Rubinfeld, Souza, Albert, Munemitsu, Polakis: "The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin." in: The Journal of biological chemistry, Vol. 270, Issue 10, pp. 5549-55, 1995

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN969072) Figure 1: Flow cytometric analysis of A549 cells using CTNNB1 mouse mAb (green) and n...
Immunocytochemistry (ICC) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN969072) Figure 2: Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using ...
Immunohistochemistry (IHC) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN969072) Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues us...
Western Blotting (WB) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (ABIN969072) Figure 4: Western blot analysis using CTNNB1 mouse mAb against CTNNB1-hIgGFc transfec...