You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human DKK4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended DKK4 Antibody (supplied by: Log in to see )

Antigen
Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) Antibodies
  • Dkk-4
  • DKK-4
  • RGD1563172
Epitope
AA 7-36, N-Term
54
21
16
5
3
2
2
2
2
1
1
Reactivity
Human
93
19
6
2
1
1
1
1
Host
Rabbit
87
15
3
Clonality
Polyclonal
Conjugate
This DKK4 antibody is un-conjugated
8
8
7
7
7
7
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
90
61
29
10
2
2
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN357073
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN357074 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 2
0.0008982679 ABIN388357 IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 3
0.0008982679 ABIN388358 IHC (p) WB Rabbit Ig AA 188-217, C-Term Log in to see Polyclonal
0.0008982679 ABIN1101148 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0008982679 ABIN1733673 IHC (p) ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
0.0008982679 ABIN1840809 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN1867579 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN4305320 IHC IHC (p) Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN2767083 IHC (p) WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-DKK4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-DKK4 Antibodies

Application / Reactivity Human
ELISA 58 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Western Blotting (WB) 84 Antibodies

General

Antigen Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) Antibodies
Epitope AA 7-36, N-Term
(54), (21), (16), (5), (3), (2), (2), (2), (2), (1), (1)
Reactivity Human
(93), (19), (6), (2), (1), (1), (1), (1)
Host Rabbit
(87), (15), (3)
Clonality
Polyclonal
Conjugate This DKK4 antibody is un-conjugated
(8), (8), (7), (7), (7), (7)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(90), (61), (29), (10), (2), (2), (2)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-DKK4 Antibody

Target Details DKK4 Application Details Handling References for anti-DKK4 Antibody (ABIN357073) Images
Sequence DKK4
Specificity This antibody detects DKK4 at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 7~36 amino acids from the N-terminal region of Human DKK4
Isotype Ig

Target Details DKK4

Product Details anti-DKK4 Antibody Application Details Handling References for anti-DKK4 Antibody (ABIN357073) Images back to top
Antigen
Alternative Name Dickkopf-4 (DKK4) (DKK4 Antibody Abstract)
Background DKK4, like DKK1, DKK2, and DKK3, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis detected no expression of DKK4, but RT-PCR analysis detected DKK4 expression in cerebellum, T-cell, esophagus, and lung cDNA libraries. DKK4 blocks Xenopus Wnt8, Wnt3a, and Wnt2b, but not Dsh or Fz8, induction of a secondary axis in frog embryos, indicating that DKKs antagonize WNT function upstream of WNT receptors.Synonyms: Dickkopf-related protein 4, Dkk-4
Molecular Weight 24875 Da
Gene ID 27121, 9606
UniProt Q9UBT3
Pathways WNT Signaling

Application Details

Product Details anti-DKK4 Antibody Target Details DKK4 Handling References for anti-DKK4 Antibody (ABIN357073) Images back to top
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-DKK4 Antibody Target Details DKK4 Application Details References for anti-DKK4 Antibody (ABIN357073) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-DKK4 Antibody (ABIN357073)

Product Details anti-DKK4 Antibody Target Details DKK4 Application Details Handling Images back to top
Background publications

Yoshida, Satoh, Mitsuya, Tate: "Assignment of the human dickkopf (Xenopus) homolog 4 (DKK4) to chromosome 8p11.2-->p11.1 by fluorescence in situ hybridization." in: Cytogenetics and cell genetics, Vol. 94, Issue 1-2, pp. 88-9, 2001

Krupnik, Sharp, Jiang, Robison, Chickering, Amaravadi, Brown, Guyot, Mays, Leiby, Chang, Duong, Goodearl, Gearing, Sokol, McCarthy: "Functional and structural diversity of the human Dickkopf gene family." in: Gene, Vol. 238, Issue 2, pp. 301-13, 1999

Images

Product Details anti-DKK4 Antibody Target Details DKK4 Application Details Handling References for anti-DKK4 Antibody (ABIN357073) back to top
Supplier Images
 image for anti-DKK4 antibody (Dickkopf Homolog 4 (Xenopus Laevis)) (AA 7-36) (ABIN357073) anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 7-36), (N-Term) antibody
 image for anti-DKK4 antibody (Dickkopf Homolog 4 (Xenopus Laevis)) (AA 7-36) (ABIN357073) anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 7-36), (N-Term) antibody (Image 2)
 image for anti-DKK4 antibody (Dickkopf Homolog 4 (Xenopus Laevis)) (AA 7-36) (ABIN357073) anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 7-36), (N-Term) antibody (Image 3)