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GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).. Additionally we are shipping Centaurin beta 2 Proteins (5) and and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal Centaurin beta 2 Primary Antibody for IHC (p), IHC - ABIN250039
Jackson, Brown, Nie, Miura, Foroni, Sun, Hsu, Donaldson, Randazzo: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. in The Journal of cell biology 2000
The down-regulation of circRNA-ACAP2 promoted miR (show MLXIP Antibodies)-21-5p expression, which further suppressed the transcription and translation of Tiam1 (show TIAM1 Antibodies).
Data suggest that Rab35 (show RAB35 Antibodies), interacting with TBC1D10A (show TBC1D10A Antibodies), functions in vascular endothelial cells as a negative regulator of histamine-evoked, Ca2 (show CA2 Antibodies)+-dependent Weibel-Palade body exocytosis, most likely acting through the downstream effectors ACAP2 and Arf6 (show ARF6 Antibodies). (Rab35 (show RAB35 Antibodies) = rab (show HRB Antibodies) GTP-binding protein (show HCAR3 Antibodies) 53 (show IGFBP3 Antibodies); TBC1D10A (show TBC1D10A Antibodies) = TBC1 domain family member 10A (show TBC1D10A Antibodies); ACAP2 = centaurin beta2; Arf6 (show ARF6 Antibodies) = ADP-ribosylation factor 6 (show ARF6 Antibodies))
ACAP2 is a functional homolog of C. elegans CNT-1 (show SLC28A1 Antibodies) and its inactivation or downregulation in human cells may contribute to cancer development
ACAP2 has robust, constitutive Arf6 (show ARF6 Antibodies) GAP activity in vivo, with little activity toward Arf1 (show ARF1 Antibodies).
Centaurin beta2/KIAA0041, is a member of the centaurin family of ADP-ribosylation factor (show ARF1 Antibodies) directed GTPase (show RACGAP1 Antibodies)-activating proteins. Binding of phosphoinositides to a pleckstrin (show PLEK Antibodies) homology domain may regulate subcellular localisation and activity.
Rab35 (show RAB35 Antibodies) regulates phagosome formation through recruitment of ACAP2 in macrophages during FcgammaR-mediated phagocytosis.
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
Arf GAP with coiled coil, ANK repeat and PH domains 2
, arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
, centaurin, beta 2
, ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
, arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2-like