anti-CD22 Molecule (CD22) Antibodies

Mediates B-cell B-cell interactions. Additionally we are shipping CD22 Proteins (32) and CD22 Kits (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD22 12483 P35329
CD22 933 P20273
CD22 308501  
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Top anti-CD22 Antibodies at antibodies-online.com

Showing 10 out of 716 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Anti- CD22 Picoband antibody, IHC(P) IHC(P): Human Tonsil Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CD22 antibody,  IHC(P) IHC(P): Human Tonsil Tissue Anti-CD22 antibody,  Western blotting WB: RAJI Cell Lysate 100 μg Log in to see 4 to 6 Days
$280.00
Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-CD22 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-CD22 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>THP-1 cell lysate WB Suggested Anti-CD22 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse FITC FACS, IFA   2 mL Log in to see 5 to 7 Days
$370.09
Details
Human Mouse PE FACS, IFA 2 mL Log in to see 5 to 7 Days
$416.09
Details
Human Mouse Un-conjugated FACS, IFA   0.2 mg Log in to see 5 to 7 Days
$301.09
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Mouse Rat PE FACS 0.1 mg Log in to see 6 to 8 Days
$308.00
Details

CD22 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD22 Antibodies

  1. Human Monoclonal CD22 Primary Antibody for FACS, IFA - ABIN1741591 : Li, Shen, Ghetie, May, Till, Ghetie, Uhr, Janossy, Thorpe, Amlot: The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies. in Cellular immunology 1989 (PubMed)
    Show all 14 Pubmed References

  2. Human Monoclonal CD22 Primary Antibody for FACS, IFA - ABIN1741590 : Dörken, Pezzutto, Moldenhauer, Schwartz, Kiesel, Hunstein: An immunoenzymatic staining assay (ISA) for the rapid screening of monoclonal antibodies detecting membrane and cytoplasmic antigens. in Journal of immunological methods 1986 (PubMed)
    Show all 14 Pubmed References

  3. Human Monoclonal CD22 Primary Antibody for FACS, IFA - ABIN1741592 : Mason, Stein, Gerdes, Pulford, Ralfkiaer, Falini, Erber, Micklem, Gatter: Value of monoclonal anti-CD22 (p135) antibodies for the detection of normal and neoplastic B lymphoid cells. in Blood 1987 (PubMed)
    Show all 14 Pubmed References

  4. Horse (Equine) Polyclonal CD22 Primary Antibody for WB - ABIN611290 : Bartoli, Gu, Tsai, Venema, Brooks, Marrero, Caldwell: Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells. in The Journal of biological chemistry 2000 (PubMed)
    Show all 8 Pubmed References

  5. Human Polyclonal CD22 Primary Antibody for WB - ABIN611291 : Bromberg, Darnell: The role of STATs in transcriptional control and their impact on cellular function. in Oncogene 2000 (PubMed)
    Show all 8 Pubmed References

  6. Human Monoclonal CD22 Primary Antibody for ICC, FACS - ABIN1724888 : Kawasaki, Rademacher, Paulson: CD22 regulates adaptive and innate immune responses of B cells. in Journal of innate immunity 2011 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CD22 Primary Antibody for ICC, FACS - ABIN1724887 : Tuscano, Kato, Pearson, Xiong, Newell, Ma, Gandara, ODonnell: CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy. in Cancer research 2012 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal CD22 Primary Antibody for IHC (fro), FACS - ABIN2689094 : Clark: CD22, a B cell-specific receptor, mediates adhesion and signal transduction. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal CD22 Primary Antibody for IHC (p), WB - ABIN3043235 : Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: S100+ cells: a new neuro-immune cross-talkers in lymph organs. in Scientific reports 2013 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal CD22 Primary Antibody for FACS, IHC (p) - ABIN3043390 : Yu, Li, Li, Zang, Liu: TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice. in Biological trace element research 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD22 Interaction Partners

Mouse (Murine) CD22 Molecule (CD22) interaction partners

  1. Thus, proximity labeling with tyramide appears to be a useful method to identify cis (show CISH Antibodies)-ligands and to analyze their interaction with the lectins.

  2. This combined approach suggests that the inhibitory function of CD22 is influenced by its nanoscale organization and is ensured by its fast diffusion enabling a "global BCR (show BCR Antibodies) surveillance" at the plasma membrane.

  3. results demonstrate that loss of high affinity CD22 ligands on GC B (show NPR2 Antibodies)-cells occurs in both mice and humans through alternative mechanisms, unmasking CD22 relative to naive and memory B-cells

  4. A noncatalytic role for CD45 (show PTPRC Antibodies) in regulating tonic, but not antigen-mediated, B-cell antigen receptor (BCR (show BCR Antibodies)) signaling through modulation of the function of the inhibitory coreceptor CD22, was identified.

  5. CD22 is recruited to the immunological synapse by sialic acid ligands on the Ag-bearing cells, producing a tolerogenic signal involving Lyn (show LYN Antibodies) and the proapoptotic factor BIM (show BCL2L11 Antibodies) that promotes deletion of the B cell and failure of mice to develop Abs to the Ag upon subsequent challenge.

  6. These data assign a key role to CCL22 (show CCL22 Antibodies) in Treg recruitment in the protection of NOD mice against type 1 diabetes following the treatment with G-CSF (show CSF3 Antibodies).

  7. Thus, CD22 plays an essential role in controlling West Nile virus infection by governing cell migration and CD8 (show CD8A Antibodies)(+) T cell responses.

  8. that neither B cells nor CD22 are critical for the immediate antiinflammatory activity of IVIgs in mouse models of rheumatoid arthritis and ITP (show ITPA Antibodies).

  9. Increased red cell turnover in a line of CD22-deficient mice is caused by Gpi1c: a model for hereditary haemolytic anaemia.

  10. novel expression pattern and tissue eosinophilia-regulating function for the "B cell-specific" inhibitory molecule CD22 on GI eosinophils.

Human CD22 Molecule (CD22) interaction partners

  1. Here the authors structurally characterize the ectodomain of CD22 and present its crystal structure with the bound therapeutic antibody epratuzumab, which gives insights into the mechanism of inhibition of B-cell activation (show BLNK Antibodies).

  2. hCD22 transgenic mice develop normal humoral responses in a peanut allergy oral sensitization model. Homing of B cells to Peyer's patches was partially rescued by expression of hCD22 compared with CD22(-/-) B cells, although not to wild-type levels.

  3. Diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy reduced disease burden in a non-Hodgkin lymphoma mouse model.

  4. Siglec-1 (show SIGLEC1 Antibodies) and Siglec-2 are potential biomarkers in autoimmune disease. (Review)

  5. We aimed to screen exons 9-14 of the CD22 gene, which is a mutational hot spot region in B-precursor acute lymphoblastic leukemia (pre-B ALL) patients. Nine variants, of which two novel, were found. Novel variants were in introns 10 and 13. Gly745Asp (rs10406069) variant was missense and Cys790Arg (rs79438722) variant was silent.

  6. Anti-CD22-magnetic nanoparticles-doxorubicin inhibited the proliferation of Raji cells, significantly increased the uptake of doxorubicin, and induced apoptosis.

  7. results demonstrate that loss of high affinity CD22 ligands on GC B (show NPR2 Antibodies)-cells occurs in both mice and humans through alternative mechanisms, unmasking CD22 relative to naive and memory B-cells

  8. MicroRNA-19a and CD22 Comprise a Feedback Loop for B Cell Response in Sepsis.

  9. These results suggest that the in vivo mechanism of non-ligand-blocking epratuzumab may, in part, involve the unmasking of CD22 to facilitate the trans-interaction of B cells with vascular endothelium.

  10. By using integrative genomics and analysing the relationships of COPD (show ARCN1 Antibodies) phenotypes with SNPs and gene expression in lung tissue, we identified CST3 (show CST3 Antibodies) and CD22 as potential causal genes for airflow obstruction.

CD22 Antigen Profile

Protein Summary

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins\; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Gene names and symbols associated with anti-CD22 Molecule (CD22) Antibodies

  • CD22 antigen (Cd22) antibody
  • CD22 molecule (CD22) antibody
  • CD22 molecule (Cd22) antibody
  • A530093D23 antibody
  • Lyb-8 antibody
  • Lyb8 antibody
  • siglec-2 antibody
  • SIGLEC2 antibody

Protein level used designations for anti-CD22 Molecule (CD22) Antibodies

B-cell receptor CD22 , B-lymphocyte cell adhesion molecule , BL-CAM , T-cell surface antigen Leu-14 , sialic acid-binding Ig-like lectin 2 , siglec-2 , CD22 antigen , sialic acid binding Ig-like lectin 2 , Sialic acid-binding Ig-like lectin 2

GENE ID SPECIES
12483 Mus musculus
933 Homo sapiens
514582 Bos taurus
101102835 Ovis aries
308501 Rattus norvegicus
450167 Pan troglodytes
100980861 Pan paniscus
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