CD274 Molecule (CD274) ELISA Kits

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Antibodies (374) and PD-L1 Proteins (87) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CD274 29126 Q9NZQ7
CD274 60533 Q9EP73
CD274 499342  
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Top PD-L1 ELISA Kits at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$530.53
Details
Mouse 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$545.68
Details
Rat 46.875 pg/mL 78.125-5000 pg/mL   96 Tests Log in to see 13 to 16 Days
$486.50
Details
Rabbit
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
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Dog
  96 Tests Log in to see 15 to 18 Days
$707.14
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Monkey
  96 Tests Log in to see 15 to 18 Days
$707.14
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Cow
  96 Tests Log in to see 15 to 18 Days
$707.14
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Chicken
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced PD-L1 ELISA Kits

  1. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN417524 : Curry, Lawrence, Burden: Ovarian sympathectomy in the golden hamster: effects on estrous cyclicity and follicular development. in Experimental and clinical endocrinology 1986 (PubMed)
    Show all 14 Pubmed References

  2. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN577883 : Atesoglu, Tarkun, Demirsoy, Geduk, Mehtap, Batman, Kaya, Cekmen, Gulbas, Hacıhanefioglu: Soluble Programmed Death 1 (PD-1) Is Decreased in Patients With Immune Thrombocytopenia (ITP): Potential Involvement of PD-1 Pathway in ITP Immunopathogenesis. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2014 (PubMed)

  3. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN579638 : Baral, Ye, Jiang, Yao, Mao: B7-H3 and B7-H1 expression in cerebral spinal fluid and tumor tissue correlates with the malignancy grade of glioma patients. in Oncology letters 2014 (PubMed)

More ELISA Kits for PD-L1 Interaction Partners

Human CD274 Molecule (CD274) interaction partners

  1. Programmed death-ligand 1 is expressed in a significant number of the uterine cervical carcinomas

  2. PD-L1 expression is detectable in two distinct cell populations in the peripheral blood of lung cancer patients and is associated with worse survival.

  3. Although hsa_circ_0020397 did not influence miR (show MLXIP ELISA Kits)-138 expression per se, has_circ_0020397 did inhibit miR (show MLXIP ELISA Kits)-138 activity, as examined via the expression of miR (show MLXIP ELISA Kits)-138 targets telomerase reverse transcriptase (TERT (show TERT ELISA Kits)) and programmed death-ligand 1 (PD-L1).

  4. Our study demonstrates a cross-talk between PARPi and tumor-associated immunosuppression and provides evidence to support the combination of PARPi and PD-L1 or PD-1 (show PDCD1 ELISA Kits) immune checkpoint blockade as a potential therapeutic approach to treat breast cancer

  5. obtained 18 pair-wise interactions within and between the NLRC5 ad PD-L1 genes and 6 more when IFNGR (show IFNGR1 ELISA Kits) variants were added

  6. PIPKIgamma promotes the transcription of the PD-L1 gene by activating the NF-kappaB (show NFKB1 ELISA Kits) pathway in these cells. These results demonstrate that PIPKIgamma-dependent expression of PD-L1 is likely important for the progression of triple negative breast cancer.

  7. Therefore, in Crohn's disease intestinal antigen taken up by lymphoid patch APCs (show APCS ELISA Kits) will be presented without PD-L1 induced tolerogenic signalling, perhaps initiating disease.

  8. results indicate that PD-L1-expressing dysplastic epithelial and recruited subepithelial cells in oral precancerous legions may evade the host immune system, and that the inhibition of PD-1 (show PDCD1 ELISA Kits)/PD-L1 pathway may potentially prevent malignant transformation of oral precancerous legions as well as can treat advanced cancers

  9. PD-L1 expression was apparent in 10.4% of LCNEC and 5.8% of SCLC tumors, and was not observed in carcinoid tumors.

  10. Our findings indicate that PD-L1 expression is a promising biomarker for the prognosis of breast cancer, and may be helpful to clinicians aiming to select the appropriate immunotherapy for breast cancer.

Mouse (Murine) CD274 Molecule (CD274) interaction partners

  1. In estrogen receptor (show ESR1 ELISA Kits) negative breast cancer cells targeting of IL-17A (show IL17A ELISA Kits) inhibited PDL1 expression in the tumor microenvironment, decreasing the percentage of Treg cells in tumor-infiltrating lymphocytes, and promoting CD4 (show CD4 ELISA Kits)+ and CD8 (show CD8A ELISA Kits)+ T cells to secrete interferon gamma (show IFNG ELISA Kits).

  2. Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8 (show CD8A ELISA Kits)+ T Cells co-expressing PD-1 (show PDCD1 ELISA Kits) and LAG-3 (show LAG3 ELISA Kits) inhibitory receptors.

  3. Genetic ablation of a single immune-regulatory molecule in this model [i.e., B7-homolog 1 (B7-H1, PD-L1)] not only significantly increased incidence of spontaneous CNS autoimmunity and aggravated disease course, especially in the later stages of disease, but also importantly resulted in encephalitogenic T-cell infiltration and lesion formation in normally unaffected brain regions.

  4. Studied the possible role of PD-L1 on malignant melanoma initiating cells (MMICs). Found blocking of PD-L1 in melanoma cell lines impaired tumorsphere formation and induced the apoptosis. Also, blocking PD-L1 inhibited tumor growth in vivo.

  5. B7-H1 induction in keratinocytes may play a crucial role in the protection from CD4 (show CD4 ELISA Kits)+ T cell-mediated tissue inflammation by exogenous antigens delivered from the mucosal surface in oral cavity

  6. Interferon (show IFNA ELISA Kits)-related secretome from direct interaction between immune cells and tumor cells is required for upregulation of PD-L1 in tumor cells.

  7. RAS signaling can upregulate tumor cell PD-L1 expression through a mechanism involving increases in PD-L1 mRNA stability via modulation of the AU-rich element-binding protein tristetraprolin (show ZFP36 ELISA Kits).

  8. Data (including data from studies in transgenic/knockout mice) suggest that T-cell expression of Mirn155 is required to limit melanoma growth; miR (show MLXIP ELISA Kits)-155, Pdcd1 (show PDCD1 ELISA Kits), Pdcd1l1, and Ctla4 (show CTLA4 ELISA Kits) appear to regulate overlapping pathways promoting antitumor immunity. [Mirn155 = microRNA 155; Pdcd1 (show PDCD1 ELISA Kits) = programmed cell death 1 (show PDCD1 ELISA Kits) protein; Pdcd1l1 = programmed cell death 1 ligand 1 protein; Ctla4 (show CTLA4 ELISA Kits) = cytotoxic T-lymphocyte-associated protein 4 (show CTLA4 ELISA Kits)]

  9. Expression of LAP/TGF-beta1 (show TGFB1 ELISA Kits), CD80 (show CD80 ELISA Kits), CD86 (show CD86 ELISA Kits) and PD-L1 is significantly increased in tumor-infiltrating B cells (TIL (show TLR1 ELISA Kits)-B) relative to splenic B cells. LAP/TGF-beta1 (show TGFB1 ELISA Kits) expression on TIL (show TLR1 ELISA Kits)-B progressively increased from 5.4+/-1.7% on day 8 to 43.1+/-6.1% by day 21 post tumor implantation.

  10. spleen-derived IFN-gamma (show IFNG ELISA Kits) induces generation of PD-L1(+)-suppressive neutrophils.

Cow (Bovine) CD274 Molecule (CD274) interaction partners

  1. This study provides novel information for the understanding of signalling through PD-L1.

Pig (Porcine) CD274 Molecule (CD274) interaction partners

  1. These results suggest that the soluble recombinant proteins may be used to prepare monoclonal antibodies to block the PD-1 (show PDCD1 ELISA Kits)/PD-L1 pathway.

  2. role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development

  3. These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 ELISA Kits) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.

  4. Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.

  5. A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.

PD-L1 (CD274) Antigen Profile

Antigen Summary

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Gene names and symbols associated with CD274 Molecule (CD274) ELISA Kits

  • CD274 molecule (CD274) antibody
  • CD274 antigen (Cd274) antibody
  • CD274 molecule (Cd274) antibody
  • A530045L16Rik antibody
  • B7-H antibody
  • B7h1 antibody
  • PD-L1 antibody
  • Pdcd1l1 antibody
  • Pdcd1lg1 antibody
  • Pdl1 antibody
  • RGD1566211 antibody

Protein level used designations for CD274 Molecule (CD274) ELISA Kits

B7 homolog 1 , CD274 antigen , PDCD1 ligand 1 , programmed cell death 1 ligand 1 , programmed death ligand 1 , CD274 molecule , programmed cell death ligand 1

GENE ID SPECIES
29126 Homo sapiens
60533 Mus musculus
427224 Gallus gallus
464981 Pan troglodytes
484186 Canis lupus familiaris
716043 Macaca mulatta
533834 Bos taurus
574058 Sus scrofa
100126721 Papio anubis
100357106 Oryctolagus cuniculus
499342 Rattus norvegicus
100722088 Cavia porcellus
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