CD274 Molecule (CD274) ELISA Kits

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CD274 CD274 29126 Q9NZQ7
Anti-Mouse CD274 CD274 60533 Q9EP73
Anti-Rat CD274 CD274 499342  
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Top PD-L1 ELISA Kits at

Showing 10 out of 53 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat 46.875 pg/mL 78.13 pg/mL - 5000 pg/mL   96 Tests Log in to see 13 to 16 Days
Human < 0.118 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
Mouse < 0.055 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days
Guinea Pig
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days

Top referenced PD-L1 ELISA Kits

  1. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN417524 : Curry, Lawrence, Burden: Ovarian sympathectomy in the golden hamster: effects on estrous cyclicity and follicular development. in Experimental and clinical endocrinology 1986 (PubMed)
    Show all 14 Pubmed References

  2. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN577883 : Atesoglu, Tarkun, Demirsoy, Geduk, Mehtap, Batman, Kaya, Cekmen, Gulbas, Hacıhanefioglu: Soluble Programmed Death 1 (PD-1) Is Decreased in Patients With Immune Thrombocytopenia (ITP): Potential Involvement of PD-1 Pathway in ITP Immunopathogenesis. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2014 (PubMed)

  3. Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN579638 : Baral, Ye, Jiang, Yao, Mao: B7-H3 and B7-H1 expression in cerebral spinal fluid and tumor tissue correlates with the malignancy grade of glioma patients. in Oncology letters 2014 (PubMed)

More ELISA Kits for PD-L1 Interaction Partners

Human CD274 Molecule (CD274) interaction partners

  1. Positive expression of PD-L1 may be a useful prognostic marker in breast cancer [META-ANALYSIS].

  2. Authors quantified programmed cell death protein 1 (PD-1 (show PDCD1 ELISA Kits))/programmed cell death-ligand 1, vascular endothelial growth factor (VEGF (show VEGF ELISA Kits))-A/VEGF (show VEGFA ELISA Kits)-C (show VEGFC ELISA Kits) expressions in lymph nodes of 103 patients who underwent sentinel lymph node biopsy.

  3. We found that PD-L1 expression was upregulated following TGF-beta (show TGFB1 ELISA Kits) induction; in contrast, it was downregulated by TGF-beta (show TGFB1 ELISA Kits) receptor-kinase inhibitors and the MET process. Furthermore, chemo-treatment increased TGF-beta (show TGFB1 ELISA Kits) expression and enhances PD-L1 expression via autocrine TGF-beta (show TGFB1 ELISA Kits) induced EMT (show ITK ELISA Kits). Analysis of clinical samples revealed a significant relationship between PD-L1 expression and EMT (show ITK ELISA Kits) status

  4. Increased PD-L1 expression is associated with gastric cancer.

  5. -L1 immunopositivity was seen in a quarter of non-small cell lung carcinomas patients in India. PDL1 positivity on immune cells may be associated with better prognosis in resected non-small cell lung carcinomas

  6. Studies indicate that programmed cell death 1 ligand 1 protein (PD-L1) expression may be very heterogeneous [Review].

  7. Programmed cell death 1 ligand 1 protein (PD-L1) expression significantly correlates with overall mutational load and KRAS protein mutational status in pulmonary sarcomatoid carcinomas.

  8. High PD-L1 expression is associated with diffuse gliomas differs with IDH mutation.

  9. PD-L1 expression in melanoma tumor cells is lower than NSCLC or renal cell carcinoma cells. The higher response rate in melanoma patients treated with PD-1 (show PDCD1 ELISA Kits) inhibitors is likely related to PD-L1 in tumor-associated inflammatory cells. Further studies are warranted to validate the predictive role of inflammatory cell PD-L1 expression in melanoma and determine its biological significance

  10. PD-L1 expression was measured in paired tumor tissue samples collected at different dates and lesions from non-small cell lung cancer patients; there was a statistically significant correlation in PD-L1 proportion scores, with a 67% concordance rate when samples were categorized into positive and negative PD-L1 expression groups

Mouse (Murine) CD274 Molecule (CD274) interaction partners

  1. an enhanced expression of PD-L1 was observed besides an increased production of IFN-gamma (show IFNG ELISA Kits) by TH2 cells.

  2. Study demonstrated that PD-L1 expression is up-regulated in the salivary glands of female NOD mice during the developmental phase of Sjgren's syndrome, which in turn hinders the development and onset of this disease in a negative feedback fashion.

  3. PD-L1 expression on tumor cells suppressed antigen-driven TNF (show TNF ELISA Kits) production by CD8 (show CD8A ELISA Kits)(+) T cells, which could be antagonized through PD-1 (show PDCD1 ELISA Kits) blockade

  4. B7-H1 suppresses p38 MAPK (show MAPK14 ELISA Kits) activation by sequestering DNA-PKcs (show PRKDC ELISA Kits) in order to preserve T cell survival

  5. Anti-PD-1 (show PDCD1 ELISA Kits)/PD-L1 therapy inhibited CMT167 orthotopic lung tumors by 95%. .Silencing PD-L1 expression in CMT167 cells resulted in smaller orthotopic tumors that remained sensitive to anti-PD-L1 therapy, whereas implantation of CMT167 cells into PD-L1(-) mice blocked orthotopic tumor growth, indicating a role for PD-L1 in both the cancer cell and the microenvironment.

  6. Combination therapies that depend on checkpoint inhibitor antibodies (Abs) such as for PD-1 (show PDCD1 ELISA Kits) or its ligand (PD-L1) together with immune stimulatory agonist Abs like anti-OX40 (show TNFRSF4 ELISA Kits) are being tested in the clinic to achieve improved antitumor effects

  7. In estrogen receptor (show ESR1 ELISA Kits) negative breast cancer cells targeting of IL-17A (show IL17A ELISA Kits) inhibited PDL1 expression in the tumor microenvironment, decreasing the percentage of Treg cells in tumor-infiltrating lymphocytes, and promoting CD4 (show CD4 ELISA Kits)+ and CD8 (show CD8A ELISA Kits)+ T cells to secrete interferon gamma (show IFNG ELISA Kits).

  8. Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8 (show CD8A ELISA Kits)+ T Cells co-expressing PD-1 (show PDCD1 ELISA Kits) and LAG-3 (show LAG3 ELISA Kits) inhibitory receptors.

  9. Genetic ablation of a single immune-regulatory molecule in this model [i.e., B7-homolog 1 (B7-H1, PD-L1)] not only significantly increased incidence of spontaneous CNS autoimmunity and aggravated disease course, especially in the later stages of disease, but also importantly resulted in encephalitogenic T-cell infiltration and lesion formation in normally unaffected brain regions.

  10. Studied the possible role of PD-L1 on malignant melanoma initiating cells (MMICs). Found blocking of PD-L1 in melanoma cell lines impaired tumorsphere formation and induced the apoptosis. Also, blocking PD-L1 inhibited tumor growth in vivo.

Cow (Bovine) CD274 Molecule (CD274) interaction partners

  1. This study provides novel information for the understanding of signalling through PD-L1.

Pig (Porcine) CD274 Molecule (CD274) interaction partners

  1. These results suggest that the soluble recombinant proteins may be used to prepare monoclonal antibodies to block the PD-1 (show PDCD1 ELISA Kits)/PD-L1 pathway.

  2. role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development

  3. These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 ELISA Kits) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.

  4. Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.

  5. A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.

PD-L1 (CD274) Antigen Profile

Antigen Summary

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Gene names and symbols associated with CD274 Molecule (CD274) ELISA Kits

  • CD274 molecule (CD274) antibody
  • CD274 antigen (Cd274) antibody
  • CD274 molecule (Cd274) antibody
  • A530045L16Rik antibody
  • B7-H antibody
  • B7h1 antibody
  • PD-L1 antibody
  • Pdcd1l1 antibody
  • Pdcd1lg1 antibody
  • Pdl1 antibody
  • RGD1566211 antibody

Protein level used designations for CD274 Molecule (CD274) ELISA Kits

B7 homolog 1 , CD274 antigen , PDCD1 ligand 1 , programmed cell death 1 ligand 1 , programmed death ligand 1 , CD274 molecule , programmed cell death ligand 1

29126 Homo sapiens
60533 Mus musculus
427224 Gallus gallus
464981 Pan troglodytes
484186 Canis lupus familiaris
716043 Macaca mulatta
533834 Bos taurus
574058 Sus scrofa
100126721 Papio anubis
100357106 Oryctolagus cuniculus
499342 Rattus norvegicus
100722088 Cavia porcellus
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