anti-Centromere Protein T (CENPT) Antibodies

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. Additionally we are shipping CENPT Kits (18) and CENPT Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CENPT 80152 Q96BT3
CENPT 320394 Q3TJM4
CENPT 307805 Q561R1
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Top anti-CENPT Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of CENPT expression in ; HepG2 cell lysate,The lane on the left is treated with the antigen-specific peptide. ABIN6273466 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of CENPT expression in transfected 293T cell line by CENPT MaxPab polyclonal antibody.Lane 1: C16orf56 transfected lysate(32.89 KDa).Lane 2: Non-transfected lysate. CENPT MaxPab polyclonal antibody. Western Blot analysis of CENPT expression in human colon. 50 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$293.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CENPT expression in HepG2 cell lysate,The lane on the left is treated with the antigen-specific peptide. 100 μg Log in to see 11 to 18 Days
$440.62
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: CENPT Antibody [NBP2-34093] - Staining of human cell line MCF7 shows positivity in nucleus. Immunohistochemistry-Paraffin: CENPT Antibody [NBP2-34093] - endometrial cancer 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

More Antibodies against CENPT Interaction Partners

Xenopus laevis Centromere Protein T (CENPT) interaction partners

  1. These results support the existence of 2 pathways for kinetochore assembly directed by CENP-C and CENP-T/W, which can be reconstituted in Xenopus egg extracts.

Human Centromere Protein T (CENPT) interaction partners

  1. Levels of centromere aberrations increase upon depletion of CENP-A, CENP-C, and CENP-T/W, during replicative senescence, and in cancer cells.

  2. report a novel disease gene encoding the constitutive inner kinetochore member CENPT, which is involved in kinetochore targeting and assembly, resulting in severe growth failure in two siblings of a consanguineous family

  3. Upon cross-linking, the entire CENPA/CENPB/CENPC/CENPT complex is nuclease-protected over an alpha-satellite dimer that comprises the fundamental unit of centromeric chromatin. We conclude that CENPA/CENPC and CENPT pathways for kinetochore assembly are physically integrated over young alpha-satellite dimers.

  4. Whereas CENP-C recruits a single MIS12:NDC80 complex, the authors show here that CENP-T binds one MIS12:NDC80 and two NDC80 complexes upon phosphorylation by the mitotic CDK1:Cyclin B complex at three distinct CENP-T sites.

  5. FACT chaperone stabilizes the soluble CENP-T/-W complex in the cell and promotes dynamics of exchange, enabling CENP-T/-W deposition at centromeres.

  6. We used a synthetic system to dissect how CenH3(CENP-A) contributes to the accumulation of CENP-C and CENP-T, two key components that are necessary for the formation of functional kinetochores

  7. CENP-T directly interacts with Ndc80, which in turn promotes KNL1/Mis12 complex recruitment at kinetochores during chromosome segregation.

  8. CSN5 regulates the stability of the inner kinetochore components CENP-T and CENP-W, providing the first direct link between CSN5 and the mitotic apparatus, highlighting the role of CSN5 as a multifunctional cell cycle regulator.

  9. CENP-T provides a structural platform for outer kinetochore assembly.

  10. results reveal the molecular function of CENP-T proteins and demonstrate how the Ndc80 complex is anchored to centromeres in a manner that couples chromosome movement to spindle dynamics

  11. The CENP-T/W complex assembles through a dynamic exchange mechanism in late S-phase and G2, is required for mitosis in each cell cycle and does not persist across cell generations.

  12. Study demonstrates that CENP-W forms a DNA-binding complex together with the CCAN component CENP-T; this complex directly associates with nucleosomal DNA and with canonical histone H3, but not with CENP-A, in centromeric regions.

  13. CENP-T exchange into centromeres is restricted to the S-phase of the cell cycle as revealed by FRAP, suggesting a coreplicational loading mechanism.

CENPT Antigen Profile

Protein Summary

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006

Gene names and symbols associated with CENPT

  • centromere protein T (cenpt) antibody
  • centromere protein T L homeolog (cenpt.L) antibody
  • centromere protein T (CENPT) antibody
  • si:ch211-225g23.1 (si:ch211-225g23.1) antibody
  • centromere protein T (Cenpt) antibody
  • C16orf56 antibody
  • CENP-T antibody
  • G630055P03Rik antibody
  • MGC145722 antibody
  • RGD1309383 antibody
  • wu:fc31h11 antibody
  • wu:fc75c05 antibody

Protein level used designations for CENPT

centromere protein T , centromere protein T-like , fc31h11 , fc75c05 , interphase centromere complex protein 22 , CENP-T

GENE ID SPECIES
779753 Xenopus (Silurana) tropicalis
100158304 Xenopus laevis
415654 Gallus gallus
454175 Pan troglodytes
562197 Danio rerio
100393620 Callithrix jacchus
80152 Homo sapiens
320394 Mus musculus
307805 Rattus norvegicus
611127 Canis lupus familiaris
513195 Bos taurus
101115894 Ovis aries
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