anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antibodies

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP2D6

• cytochrome P450 family 2 subfamily D member 6 (CYP2D6) antibody
• cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) antibody
• cytochrome 2D6 (CYP2D6) antibody
• cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) antibody
• cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) antibody
• Show all gene names
• cytochrome P450 family 2 subfamily D member 6 (cyp2d6) antibody
• cytochrome P450 2D6 (CYP2D6) antibody
• cytochrome P450 2D6-like (LOC100988273) antibody

• CPD6 antibody
• CYP2D antibody
• cyp2d2 antibody
• CYP2D6 antibody
• cyp2d6-a antibody
• Show all synonym aliases
• CYP2D7AP antibody
• CYP2D7BP antibody
• CYP2D7P2 antibody
• CYP2D8P2 antibody
• CYP2D42 antibody
• CYP2DL1 antibody
• CYPIID6 antibody
• MGC64445 antibody
• P450-DB1 antibody
• P450C2D antibody
• P450DB1 antibody

Protein level used designations for CYP2D6

cytochrome P450 2D6 , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , debrisoquine 4-hydroxylase , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , cytochrome P450 2D6-like