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CYP2D6 antibody (AA 315-347)

CYP2D6 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5647528
  • Target See all CYP2D6 Antibodies
    CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
    Binding Specificity
    • 15
    • 10
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-347
    Reactivity
    • 77
    • 22
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 73
    • 3
    • 1
    Rabbit
    Clonality
    • 64
    • 13
    Polyclonal
    Conjugate
    • 43
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2D6 antibody is un-conjugated
    Application
    • 68
    • 32
    • 28
    • 14
    • 14
    • 14
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogen
    Amino acids 315-347 (AWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM) from the human protein were used as the immunogen for the CYP2D6 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product CYP2D6 Primary Antibody
  • Application Notes
    Optimal dilution of the CYP2D6 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the CYP2D6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
    Alternative Name
    CYP2D6 (CYP2D6 Products)
    Synonyms
    CPD6 antibody, CYP2D antibody, CYP2D7AP antibody, CYP2D7BP antibody, CYP2D7P2 antibody, CYP2D8P2 antibody, CYP2DL1 antibody, CYPIID6 antibody, P450-DB1 antibody, P450C2D antibody, P450DB1 antibody, CYP2D42 antibody, MGC64445 antibody, cyp2d2 antibody, cyp2d6-a antibody, CYP2D6 antibody, cytochrome P450 family 2 subfamily D member 6 antibody, cytochrome P450, family 2, subfamily D, polypeptide 6 antibody, cytochrome 2D6 antibody, cytochrome P450 family 2 subfamily D member 6 S homeolog antibody, cytochrome P450 2D6 antibody, cytochrome P450 2D6-like antibody, CYP2D6 antibody, cyp2d6-b antibody, cyp2d6.S antibody, cyp2d6 antibody, LOC100988273 antibody
    Background
    Cytochrome P450 2D6 (CYP2D6) is one of the most important enzymes involved in the metabolism of xenobiotics in the body. It is a member of Cytochrome P450, family 2, subfamily D, polypeptide 6. This gene is mapped to chromosome 22q13.1. It has got 497 amino acid proteins which shares 73 % sequence identity with the rat protein. CYP2D6 is highly expressed in human liver and it is the major isozyme involved in the formation of N-hydroxyprocainamide, a metabolite potentially involved in the drug-induced lupus syndrome observed with procainamide.
    UniProt
    P10635
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