anti-Galactose-1-Phosphate Uridylyltransferase (GALT) Antibodies

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. Additionally we are shipping Galactose-1-Phosphate Uridylyltransferase Proteins (21) and Galactose-1-Phosphate Uridylyltransferase Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GALT 2592 P07902
GALT 298003 P43424
GALT 14430 Q03249
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Top anti-Galactose-1-Phosphate Uridylyltransferase Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GALT Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human brain 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GALT Antibody (C-term) in MDA-MB231 cell line lysates (35 µg/lane). GALT (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB Human Kidney, Tubules: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-GALT antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
$561.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of GALT using anti-GALT antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human HepG2 cell lysates,  Lane 2: human MCF-7 cell lysates.After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-GALT antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GALT at approximately 48KD. The expected band size for GALT is at 43KD. 100 μg 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis of GALT Antibody in MDA-MB231 cell line lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of GALT expression in SKOV3 (A), HepG2 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to GALT on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 1 ug/ml] GALT monoclonal antibody (M01), clone 4C11 Western Blot analysis of GALT expression in K-562 . 100 μg 11 to 12 Days
$364.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Rat Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Rat GALT Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg 13 to 16 Days
$380.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details

Top referenced anti-Galactose-1-Phosphate Uridylyltransferase Antibodies

  1. Cow (Bovine) Polyclonal GALT Primary Antibody for WB - ABIN2783382 : Karas-Kuzelicki, Pfeifer, Lukac-Bajalo: Synergistic effect of high lactase activity genotype and galactose-1-phosphate uridyl transferase (GALT) mutations on idiopathic presenile cataract formation. in Clinical biochemistry 2008 (PubMed)

More Antibodies against Galactose-1-Phosphate Uridylyltransferase Interaction Partners

Human Galactose-1-Phosphate Uridylyltransferase (GALT) interaction partners

  1. This review summarizes the current knowledge of galactosemia, in particular the putative mechanisms of neonatal and long-term complications and the molecular genetics of GALT deficiency.

  2. Although all individuals in this study showed markedly reduced RBC GALT activity, we observed significant differences in RBC GAL1P concentrations among galactosemia genotypes.

  3. Study found no statistically significant difference in the occurrence of the GALT gene mutation between Indian patients with idiopathic presenile cataract and controls.

  4. GALT mutation is associated with galactosemia.

  5. The mutational spectrum of the GALT gene in Greek galactosemia patients is presented for the first time.

  6. novel splicing mutation in GALT gene causing Galactosemia in Ecuadorian family

  7. 17 VUS (37%; 7 in ACADM, 9 in GALT, and 1 in PAH) were reclassified from uncertain (6 to benign or likely benign and 11 to pathogenic or likely pathogenic). We identified common types of missing information that would have helped make a definitive classification and categorized this information by ease and cost to obtain

  8. we present the 1.9 A resolution crystal structure of human GALT (hGALT) ternary complex, revealing a homodimer arrangement that contains a covalent uridylylated intermediate and glucose-1-phosphate in the active site, as well as a structural zinc-binding site, per monomer

  9. A novel noncoding homozygous GALT variant associated with asymptomatic galactosemia has been described in an infant of consanguineous heterozygous parents.

  10. Mutation activates a cryptic donor splice site, inducing an aberrant splicing of the GALT pre-mRNA, which in turn leads to a frameshift with inclusion of a premature stop codon.

  11. GALT activity in red blood cells of patients with galactosaemia

  12. Novel missense mutations identified in Italian galactosemic patients.

  13. In Korean population, novel GALT mutations were identified in the galactosemia patients different from those of other populations.

  14. suggests that GALT mutations are ethnic-specific and that galactosemia is a heterogeneous disorder at the molecular level

  15. In this report, we present GALT gene mutations in 56 cases of galactosemia from Turkey identified using DNA microarray resequencing.

  16. Data suggest that in classic galactosemia residual GALT activity (predicted from activity of recombinant GALT matching patient's mutation) correlates with reduced ovarian reserve (as indicted by biological marker, circulating anti-Mullerian hormone).

  17. HGALT requires a level of flexibility to function optimally and that altered folding is the underlying reason of impairment in all the variants tested here.

  18. The study determined the frequency of the two most common GALT mutations and their variants in Indian galactosemia patients.

  19. The novel GALT gene mutations included 6 missense mutations viz. Y89H, Q103R, P166A, S181F, K285R, R333L; one nonsense mutation, S307X and 3 silent mutations--Q103Q, K210K and H319H.

  20. Forty four novel variations in the GALT gene were identified, among them 27 nucleotide substitutions, in the French cohort of galactosemic patients.

Mouse (Murine) Galactose-1-Phosphate Uridylyltransferase (GALT) interaction partners

  1. Our results thus demonstrated that GalT deficiency can effect down-regulation of the PI3K/Akt growth signaling pathway in mouse fibroblasts through distinct mechanisms targeting both gene and protein expression levels.

  2. Administration of a high-galactose (40% w/w) diet to lactating homozygous GalT gene-trapped females led to lethality in over 70% of the homozygous GalT gene-trapped pups before weaning.

  3. Effects of GALT deficiency and dietary galactose on UDP-glucose pyrophosphorylase and UDP-galactose pyrophosphorylase activity and uridine diphosphate glucose expression in liver of mice with homozygous deletion of the critical regions of galt.

  4. The finding is consistent with the function of UDP galactose pyrophosphorylase as an alternate pathway of galactose metabolism.

  5. Data show that PRL signals through the short form of PRL receptor RL, and causes, iin the absence of RL, a severe ovarian pathology by repressing the expression of FOXO3 and that of its target gene Galt.

Galactose-1-Phosphate Uridylyltransferase (GALT) Antigen Profile

Protein Summary

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GALT

  • galactose-1-phosphate uridylyltransferase (GALT) antibody
  • galactose-1-phosphate uridylyltransferase (galT) antibody
  • galactose-1-phosphate uridylyltransferase (Galt) antibody
  • galactose-1-phosphate uridylyltransferase, GalT (galT) antibody
  • probable galactose-1-phosphate uridylyltransferase galtb [second part] (galT) antibody
  • UDP-glucose--galactose-1-phosphate uridylyltransferase (galT) antibody
  • GalT galactose-1-phosphate uridylyltransferase (galT) antibody
  • galactose-1-phosphate uridyl transferase (Galt) antibody
  • galactose-1-phosphate uridylyltransferase (CNM00620) antibody
  • galactose-1-phosphate uridylyltransferase (Mrub_2813) antibody
  • galactose-1-phosphate uridylyltransferase (Mesil_2395) antibody
  • galactose-1-phosphate uridylyltransferase (Trad_0989) antibody
  • galactose-1-phosphate uridylyltransferase (Igag_1846) antibody
  • galactose-1-phosphate uridylyltransferase (VDIS_RS10425) antibody
  • galactose-1-phosphate uridylyltransferase (Intca_2810) antibody
  • galactose-1-phosphate uridylyltransferase (Marky_2157) antibody
  • Galactose-1-phosphate uridylyltransferase (Selsp_1876) antibody
  • Galactose-1-phosphate uridylyltransferase (Trebr_2368) antibody
  • galactose-1-phosphate uridylyltransferase (Halhy_5538) antibody
  • galactose-1-phosphate uridylyltransferase (Theth_1357) antibody
  • Galactose-1-phosphate uridylyltransferase (Galt) antibody
  • galactose-1-phosphate uridylyltransferase S homeolog (galt.S) antibody
  • AW553376 antibody
  • CG9232 antibody
  • dGALT antibody
  • Dmel\\CG9232 antibody
  • GALT antibody

Protein level used designations for GALT

UDP-glucose--hexose-1-phosphate uridylyltransferase , gal-1-P uridylyltransferase , galactose-1-phosphate uridyl transferase , galactose-1-phosphate uridylyltransferase , galactose-1-phosphate uridylyltransferase, GalT , galactose-1-phosphate uridylyltransferase GALT , GalT galactose-1-phosphate uridylyltransferase , Galactose-1-phosphate uridylyltransferase , CG9232-PA , CG9232-PB , Galt-PA , Galt-PB , galactose-1P uridylyltransferase

GENE ID SPECIES
2592 Homo sapiens
7263966 Bifidobacterium animalis subsp. lactis AD011
1796264 Rhodopirellula baltica SH 1
7744353 Rhodococcus opacus B4
700332 Macaca mulatta
298003 Rattus norvegicus
6225189 Mycobacterium marinum M
4554475 Mycobacterium ulcerans Agy99
1091736 Mycobacterium bovis AF2122/97
2686391 Geobacter sulfurreducens PCA
506997 Bos taurus
473219 Pan troglodytes
2650665 Corynebacterium diphtheriae NCTC 13129
474751 Canis lupus familiaris
7713533 Rhodococcus erythropolis PR4
8692567 Bifidobacterium dentium Bd1
14430 Mus musculus
3255268 Cryptococcus neoformans var. neoformans JEC21
8880926 Meiothermus ruber DSM 1279
9251911 Meiothermus silvanus DSM 9946
9279972 Truepera radiovictrix DSM 17093
9717162 Ignisphaera aggregans DSM 17230
9753068 Vulcanisaeta distributa DSM 14429
10085641 Intrasporangium calvum DSM 43043
10435086 Marinithermus hydrothermalis DSM 14884
10498121 Selenomonas sputigena ATCC 35185
10580904 Treponema brennaborense DSM 12168
10589737 Haliscomenobacter hydrossis DSM 1100
10886130 Thermotoga thermarum DSM 5069
33935 Drosophila melanogaster
496084 Xenopus laevis
100726560 Cavia porcellus
100623908 Sus scrofa
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