GALT antibody (C-Term)

Catalog No. ABIN2783382

There is 1 publication for this product available. The Rabbit Polyclonal anti-GALT antibody is suitable to detect GALT in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for GALT antibody (C-Term) (ABIN2783382)

Target: GALT (Galactose-1-Phosphate Uridylyltransferase (GALT))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GALT Antibody

Binding Specificity: C-Term

Purpose: GALT Antibody - C-terminal region

Sequence: LLRSATVRKF MVGYEMLAQA QRDLTPEQAA ERLRALPEVH YHLGQKDRET

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GALT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GALT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101238

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GALT antibody (ABIN2783382)

Karas-Kuzelicki, Pfeifer, Lukac-Bajalo: "Synergistic effect of high lactase activity genotype and galactose-1-phosphate uridyl transferase (GALT) mutations on idiopathic presenile cataract formation." in: Clinical biochemistry, Vol. 41, Issue 10-11, pp. 869-74, (2008) (PubMed).

Target Details for GALT

Target: GALT (Galactose-1-Phosphate Uridylyltransferase (GALT))

Alternative Name: GALT

Background:

Background Information: Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Galactose-1-phosphate uridylyltransferase

Alternative Symbols: -

Protein Name: Galactose-1-phosphate uridylyltransferase

Molecular Weight: 43kDa

Gene ID: 2592

NCBI Accession: NP_000146

UniProt: P07902