anti-Granzyme B (GZMB) Antibodies

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. Additionally we are shipping Granzyme B Proteins (33) and Granzyme B Kits (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GZMB 3002 P10144
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Top anti-Granzyme B Antibodies at

Showing 10 out of 232 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Chimpanzee Mouse Un-conjugated EIA, FACS, IHC (fro), IF, IP   0.1 mg 6 to 8 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6266555 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis on NIH-3T3 cell lysate using Granzyme B Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GZMB Antibody (C-term) in HL-60 cell line lysates (35 µg/lane). GZMB (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GZMB antibody (N-term) in mouse stomach lysates (35 µg/lane). GZMB (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using Granzyme B Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Granzyme B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Thymus Tissue; Lane2: Mouse Lymph Node Tissue. 100 μg 13 to 16 Days
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-GZMB / Granzyme B antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101930 concentration 10 ug/ml. 50 μL 11 to 14 Days
Human Mouse Un-conjugated FACS, IP, IHC, WB   100 μg 2 to 3 Days
Human Mouse Un-conjugated FACS Flow cytometry analysis of human CD8+ peripheral blood cells with anti-human granzyme B (CLB-GB11) PE. 0.1 mg 5 to 7 Days

Top referenced anti-Granzyme B Antibodies

  1. Human Monoclonal GZMB Primary Antibody for FACS, ICC - ABIN4316065 : Dressel, Raja, Höning, Seidler, Froelich, von Figura, Günther: Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 8 Pubmed References

  2. Human Monoclonal GZMB Primary Antibody for FACS - ABIN4896044 : Dorneles, Lima, Teixeira-Carvalho, Araújo, Martins-Filho, Sriranganathan, Al Qublan, Heinemann, Lage: Immune Response of Calves Vaccinated with Brucella abortus S19 or RB51 and Revaccinated with RB51. in PLoS ONE 2015 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal GZMB Primary Antibody for FACS - ABIN1302451 : Tak, Spaeny-Dekking, Kraan, Breedveld, Froelich, Hack: The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA). in Clinical and experimental immunology 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal GZMB Primary Antibody for CyTOF, FACS - ABIN4316062 : Yan, Cao, Liu, Harrington, Bindeman, Adjei, Jang, Jen, Li, Chanana, Mansfield, Park, Markovic, Dronca, Dong: CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy. in JCI insight 2018 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal GZMB Primary Antibody for WB - ABIN516321 : Omoto, Yamanaka, Tokime, Kitano, Kakeda, Akeda, Kurokawa, Gabazza, Tsutsui, Katayama, Yamanishi, Nakanishi, Mizutani: Granzyme B is a novel interleukin-18 converting enzyme. in Journal of dermatological science 2010 (PubMed)

  6. Human Polyclonal GZMB Primary Antibody for IF (p), IHC (p) - ABIN675354 : Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

  7. Human Polyclonal GZMB Primary Antibody for ICC, IF - ABIN4316061 : Medler, Murugan, Horton, Kumar, Cotechini, Forsyth, Leyshock, Leitenberger, Kulesz-Martin, Margolin, Werb, Coussens: Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. in Cancer cell 2018 (PubMed)

  8. Human Polyclonal GZMB Primary Antibody for ICC, IF - ABIN4316064 : Chen, Chen, Choi, Sang, Chen, Zhang, Gouw, Andtbacka, Chan, Rodesch, Jimenez, Cano, Jones, Oyedeji, Martins, Hill, Schumacher, Willmore, Scaife, Ward, Morton, Randall, Lazar, Patel, Trent, Frazier et al.: Exploiting antitumor immunity to overcome relapse and improve remission duration. ... in Cancer immunology, immunotherapy : CII 2012 (PubMed)

  9. Human Monoclonal GZMB Primary Antibody for FACS - ABIN4896043 : Kreft, Verbraak, Wierenga-Wolf, van Meurs, Oostra, Laman, Hintzen: The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  10. Human Polyclonal GZMB Primary Antibody for FACS, WB - ABIN4899391 : Jiang, Canfield, Gallagher, Jiang, Jiang, Zheng, Chess: HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes. in The Journal of clinical investigation 2010 (PubMed)

More Antibodies against Granzyme B Interaction Partners

Human Granzyme B (GZMB) interaction partners

  1. These data provide additional supportive evidence that GZMB gene is an important locus for vitiligo in Han Chinese population.

  2. granzyme B is identified as a host marker to help identify latently infected tuberculosis individuals.

  3. The present review will summarize and critically examine the current knowledge regarding GzmB in inflammatory skin disease, providing an overview of both apoptotic and extracellular mechanisms, but with a focus on the extracellular roles of GzmB in skin health and disease

  4. our exploratory study suggests that EOMES, BCL6 and GZMB gene expression are aberrant within the PB T cell transcriptome of HT patients. The association of this transcription signature with the heterogeneity of HT and disease control is suggested.

  5. Serum interleukin 1 receptor antagonist (IL1RA) and granzyme B (GZMB) levels were markedly increased in Crohn's disease (CD) patients, suggesting that these markers can serve as biomarkers to identify gut inflammation.

  6. Authors found that R(48)-GzmB is a stable protein that accumulates to similar levels in activated NK cells as Q(48)-GzmB. rs8192917 polymorphism may influence antitumor activity and the effect of antitumor cellular immunotherapy.

  7. GzmA and gzmB were predominantly expressed by natural killer cells, and during abdominal sepsis, the percentage of these cells expressing gzms in peritoneal lavage fluid decreased, while the amount of expression in the gzm(+) cells increased

  8. Study provides evidence that Il10 expression is limited to migratory CD25++ regulatory T cells only.

  9. Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up

  10. Granzyme B breaches the inner membrane through Tim22, the metabolite carrier translocase pore, in a mitochondrial heat-shock protein 70-dependent manner.

  11. Differential proteomics were used to identify granzyme B substrates in three unrelated bacteria: Escherichia coli, Listeria monocytogenes, and Mycobacteria tuberculosis. Granzyme B cleaves a highly conserved set of proteins in all three bacteria, which function in vital biosynthetic and metabolic pathways that are critical for bacterial survival under diverse environmental conditions.

  12. Proteolysis by granzyme B enhances presentation of autoantigenic PAD4 epitopes in rheumatoid arthritis.

  13. our results suggest granzyme B PET imaging can serve as a quantitatively useful predictive biomarker for efficacious responses to cancer immunotherapy.

  14. Plasma GzmB levels may reflect the degree of pruritus and dermatitis in patients with atopic dermatitis

  15. These results suggest the critical importance of miR-378 in the regulation of GrzB expression and a protective role for GrzB in controlling dengue virus replication in vivo.

  16. Analysis of infiltrating granzyme B-expressing T cells at the invasive borders of the colon tumors revealed a significant difference in expression granzyme by race underlining decreased antitumor cytotoxic immunity in African Americans.

  17. Increased TIM3+CD8+T cells with lower perforin and granzyme B expression and higher CD95 expression in MDS patients were observed.

  18. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  19. granzyme-B levels were found to be significantly associated with increased insulin resistance in adolescent polycystic ovary syndrome patients. Additionally, elevated levels of serum granzyme-B were predictive for increased cardiovascular risk in PCOS patients

  20. results suggest that enhanced IL-21R expression of CD19(+)CD5(+) B cells and production of IL-21 by iNKT cells may play an important role in the pathogenesis of pSS by regulating CD19(+)CD5(+) B cell functions and increasing GrB production, presumably leading to a counter-regulatory effect in the disease.

Granzyme B (GZMB) Antigen Profile

Protein Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Gene names and symbols associated with anti-Granzyme B (GZMB) Antibodies

  • granzyme B (GZMB) antibody
  • CCPI antibody
  • CGL-1 antibody
  • CGL1 antibody
  • CSP-B antibody
  • CSPB antibody
  • CTLA1 antibody
  • CTSGL1 antibody
  • HLP antibody
  • SECT antibody

Protein level used designations for anti-Granzyme B (GZMB) Antibodies

C11 , CTLA-1 , T-cell serine protease 1-3E , cathepsin G-like 1 , cytotoxic T-lymphocyte proteinase 2 , cytotoxic serine protease B , fragmentin 2 , fragmentin-2 , granzyme B , human lymphocyte protein

3002 Homo sapiens
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