anti-Influenza Nucleoprotein Antibodies

Encapsidates the negative strand viral RNA, protecting it from nucleases.

Data Quality
  • 17
  • 32
Type
  • 299
    Primary antibodies
Antigen
  • 299
Reactivity
  • 128
  • 102
  • 45
  • 12
  • 3
Application
  • 239
  • 119
  • 66
  • 18
  • 16
Host
  • 250
  • 49
Clonality
  • 249
  • 50
Clone
  • 7
  • 5
  • 4
  • 4
  • 3
Binding Specificity
  • 14
  • 9
  • 4
  • 4
  • 3
Conjugate
  • 250
  • 17
  • 13
  • 8
  • 1
Isotype
  • 89
  • 71
  • 61
  • 54
  • 9
Format
  • 248
  • 3
Suggested next Filters
299 Products
ReactivityInfluenza A Virus H2N2
Application IC, IF, IP, IHC, ELISA, WB
Order details Cat. No. ABIN2452039
$494.62
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityInfluenza A Virus H2N2
Application IC, IHC, ELISA, WB
Order details Cat. No. ABIN2452038
$494.62
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityInfluenza A Virus
Application ELISA, WB
Order details Cat. No. ABIN1724685
$393.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application ELISA
Order details Cat. No. ABIN5707184
$258.00
0.5 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application ELISA
Order details Cat. No. ABIN5707185
$258.00
0.5 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Mouse, Monoclonal (FluA-NP 2C9), IgG2a
ReactivityInfluenza A Virus
Application ELISA
Order details Cat. No. ABIN377011
$258.00
0.5 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Mouse, Monoclonal (FluA-NP 4F1), IgG1
ReactivityInfluenza A Virus
Application ELISA
Order details Cat. No. ABIN377012
$294.00
0.5 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza A Virus
Application ELISA
Order details Cat. No. ABIN5707181
$324.00
1 mL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application ELISA
Order details Cat. No. ABIN5707182
$324.00
1 mL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application ELISA
Order details Cat. No. ABIN5707183
$324.00
1 mL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application PrA, ELISA, WB
Order details Cat. No. ABIN235669
$441.47
1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application PrA, ELISA, WB
Order details Cat. No. ABIN235668
$441.47
1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application ELISA, WB
Order details Cat. No. ABIN235671
$441.47
1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza B Virus
Application PrA, ELISA, WB
Order details Cat. No. ABIN235670
$441.47
1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityInfluenza A Virus H1N1
Application PrA, ELISA, WB
Order details Cat. No. ABIN235631
$470.80
1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
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Influenza Nucleoprotein (NP) Antigen Profile

Protein Summary

Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus (By similarity).

Gene names and symbols associated with NP

  • nucleoprotein (NP) antibody
GENE ID SPECIES
956539 Influenza B virus
956531 Influenza A virus
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