anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) Antibodies

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. Additionally we are shipping INPP5B Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
INPP5B 16330 Q8K337
INPP5B 362590  
INPP5B 3633 P32019
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Top anti-INPP5B Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-INPP5B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Hela cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of CEM cells using INPP5B / 5PTase 2 Antibody (C-term) Cat.-No AP52214PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle reacted with INPP5B / 5PTase 2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL 6 to 8 Days
$484.00
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis in CEM cell line lysates (35ug/lane). INPP5B antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB   100 μL 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using INPP5B, antibody at 1:100 dilution. WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated WB INPP5B antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of INPP5B expression in transfected 293T cell line by INPP5B MaxPab polyclonal antibody.Lane 1: INPP5B transfected lysate(85.00 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to INPP5B on HeLa cell. [antibody concentration 30 ug/ml] 100 μg 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of INPP5B expression in transfected 293T cell line by INPP5B MaxPab polyclonal antibody.Lane 1: INPP5B transfected lysate(82.28 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB   200 μL 11 to 16 Days
$658.43
Details

Top referenced anti-INPP5B Antibodies

  1. Dog (Canine) Polyclonal INPP5B Primary Antibody for WB - ABIN2785875 : Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. in Cell 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against INPP5B Interaction Partners

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) interaction partners

  1. These results suggest that the functions of OCRL/INPP5B and proton-chloride exchange transporter 5 converge on shared mechanisms, the impairment of which has a dramatic effect on proximal tubule endocytosis

  2. study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl function

  3. ADAM cleavage was only modestly impaired in numerous Inpp5b-null males and varied between individual animals.

  4. These results indicate a functional overlap of Ocrl and Inpp5b in most cell lineages, especially in extraembryonic tissues.

  5. Inpp5b role in the regulation of cell adhesion in the testis and in the formation of junctional complexes with neighboring cells

  6. 72-5ptase expression promoted GLUT4 trafficking via a Rab11-dependent pathway but not by Rab5-mediated endocytosis. Therefore, endogenous PtdIns(3)P at the plasma membrane promotes GLUT4 translocation.

Human Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) interaction partners

  1. OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells

  2. The crystal structures of human INPP5B in complex with phosphoinositide substrate analogs revealed a membrane interaction patch likely to assist in sequestering substrates from the lipid bilayer.

  3. study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl function

  4. The homologous phosphatase Inpp5b was unable to complement the Ocrl1-dependent cell migration defect.

  5. INPP5B is also localised to the early secretory pathway including the Golgi apparatus and ER-to-Golgi intermediate compartment (ERGIC).

  6. The NH2-terminal region of OCRL, but not of INPP5B, binds clathrin heavy chain.

INPP5B Antigen Profile

Protein Summary

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with INPP5B

  • inositol polyphosphate-5-phosphatase B (INPP5B) antibody
  • type II inositol 1,4,5-trisphosphate 5-phosphatase-like (LOC100224437) antibody
  • inositol polyphosphate-5-phosphatase B L homeolog (inpp5b.L) antibody
  • inositol polyphosphate 5-phosphatase OCRL-1 (LOC100159919) antibody
  • inositol polyphosphate-5-phosphatase B (Inpp5b) antibody
  • 5PTase antibody
  • 75kDa antibody
  • AW260155 antibody
  • INPP5P antibody

Protein level used designations for INPP5B

inositol polyphosphate-5-phosphatase, 75kDa , inositol polyphosphate-5-phosphatase, 75kDa-like , type II inositol-1,4,5-trisphosphate 5-phosphatase-like , 5PTase , inositol polyphosphate-5-phosphatase, 75 kDa , phosphoinositide 5-phosphatase , type II inositol 1,4,5-trisphosphate 5-phosphatase , type II inositol-1,4,5-trisphosphate 5-phosphatase , 75 kDa inositol polyphosphate-5-phosphatase

GENE ID SPECIES
419609 Gallus gallus
456767 Pan troglodytes
538291 Bos taurus
716851 Macaca mulatta
100054559 Equus caballus
100224437 Taeniopygia guttata
100350043 Oryctolagus cuniculus
100381066 Xenopus laevis
100159919 Acyrthosiphon pisum
100512110 Sus scrofa
16330 Mus musculus
362590 Rattus norvegicus
3633 Homo sapiens
100686373 Canis lupus familiaris
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