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INPP5B Products

(Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))

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Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Featured INPP5B Categories

INPP5B Antibodies

High quality antibodies with extensive validation data.

INPP5B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended INPP5B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7173964
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654447
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7245311
Quantity 200 μL
Datasheet Datasheet

Recommended INPP5B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6226066
Quantity 96 tests
Datasheet Datasheet

Recommended INPP5B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307955
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our INPP5B products

Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).

Synonyms and alternative names related to INPP5B

inositol polyphosphate-5-phosphatase B (INPP5B), type II inositol 1,4,5-trisphosphate 5-phosphatase-like (LOC100224437), inositol polyphosphate-5-phosphatase B L homeolog (inpp5b.L), inositol polyphosphate 5-phosphatase OCRL-1 (LOC100159919), inositol polyphosphate-5-phosphatase B (Inpp5b), 5PTase, 75kDa, AW260155, INPP5P

Protein level used designations for INPP5B

  • inositol polyphosphate-5-phosphatase, 75kDa
  • inositol polyphosphate-5-phosphatase, 75kDa-like
  • type II inositol-1,4,5-trisphosphate 5-phosphatase-like
  • 5PTase
  • inositol polyphosphate-5-phosphatase, 75 kDa
  • phosphoinositide 5-phosphatase
  • type II inositol 1,4,5-trisphosphate 5-phosphatase
  • type II inositol-1,4,5-trisphosphate 5-phosphatase
  • 75 kDa inositol polyphosphate-5-phosphatase
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