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MCAM Proteins

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue.

25 results:

Melanoma Cell Adhesion Molecule (MCAM) (AA 1-559), (Extracellular Domain) protein (His tag) Protein

MCAM Reactivity: Human Source: Human Cells Recombinant > 98 % as determined by SDS-PAGE SDS
Pubmed 2
Catalog No. ABIN2002107
$179.33
Plus shipping costs $45.00
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 1-563), (Extracellular Domain) protein (His tag) Protein

MCAM Reactivity: Mouse Source: Human Cells Recombinant > 98 % as determined by SDS-PAGE SDS
Pubmed 1
Catalog No. ABIN2008310
$179.33
Plus shipping costs $45.00
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) protein (GST tag) Protein

MCAM Reactivity: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Pubmed 1
Catalog No. ABIN1310514
$338.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 1-559), (Extracellular Domain) protein (Fc Tag) Protein

MCAM Reactivity: Human Source: Human Cells Recombinant > 95 % as determined by SDS-PAGE SDS
Pubmed 4
Catalog No. ABIN2002106
$357.92
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 24-646) protein (His-DYKDDDDK-Strep II Tag) Protein

MCAM Reactivity: Human Source: HEK-293 Cells Recombinant PI, SDS, ELISA, WB
Catalog No. ABIN2752854
$533.33
Plus shipping costs $45.00
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 24-648) protein (rho-1D4 tag) Protein

MCAM Reactivity: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3136648
$5,919.98
Plus shipping costs $45.00 and $24.00 dry ice
0.25 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 24-646) protein (rho-1D4 tag) Protein

MCAM Reactivity: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3093925
$8,431.43
Plus shipping costs $45.00 and $24.00 dry ice
0.5 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 24-559) protein (His tag) Protein

MCAM Reactivity: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3083987
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 24-563) protein (His tag) Protein

MCAM Reactivity: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3126705
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days

Melanoma Cell Adhesion Molecule (MCAM) (AA 324-565) protein (His tag) Protein

MCAM Reactivity: Human Source: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
Catalog No. ABIN1877504
$360.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 13 Business Days
  • Type Protein
    • Protein
  • Target Melanoma Cell Adhesion Molecule (MCAM)
    • Melanoma Cell Adhesion Molecule (MCAM)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • CD40 Ligand (CD40LG)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Interleukin 15 (IL15)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Interleukin 33 (IL33)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Screening Assay (ScA)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Insect Cells
    • Human Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • Yeast
  • Binding Specificity
    • AA 24-559
    • Extracellular Domain
    • AA 1-559
    • AA 24-646
    • AA 1-563
    • AA 1-646
    • AA 224-464
    • AA 24-560
    • AA 24-563
    • AA 24-648
    • AA 323-560
    • AA 324-565
    • AA 433-647
    • AA 50-646
    • partial
  • Conjugate
    • Un-conjugated
    • His tag
    • Fc Tag
    • rho-1D4 tag
    • GST tag
    • His-DYKDDDDK-Strep II Tag
    • Myc-DYKDDDDK Tag
    • S tag,His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

MCAM Protein Profile

Protein Summary

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Gene names and symbols associated with MCAM

  • melanoma cell adhesion molecule (MCAM) antibody
  • melanoma cell adhesion molecule (Mcam) antibody
  • melanoma cell adhesion molecule b (mcamb) antibody
  • 1-gicerin antibody
  • AV025631 antibody
  • cd146 antibody
  • CD149 antibody
  • gicerin antibody
  • id:ibd3512 antibody
  • MCAM antibody
  • Muc18 antibody
  • s-endo antibody
  • s-gicerin antibody

Protein level used designations for MCAM

Gicerin , S-endo 1 endothelial-associated antigen , cell surface glycoprotein MUC18 , cell surface glycoprotein P1H12 , melanoma adhesion molecule , melanoma-associated antigen A32 , melanoma-associated antigen MUC18 , gicerin , l-gicerin , l-gicerin protein , cell adhesion molecule , HEMCAM , melanoma cell adhesion molecule , cell surface glycoprotein MUC18-like

GENE ID SPECIES
4162 Homo sapiens
78967 Rattus norvegicus
84004 Mus musculus
281301 Bos taurus
338313 Danio rerio
448832 Gallus gallus
489368 Canis lupus familiaris
733617 Sus scrofa
744688 Pan troglodytes
100071414 Equus caballus
100454353 Pongo abelii
100470323 Ailuropoda melanoleuca
100718224 Cavia porcellus

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