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Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Additionally we are shipping MAP1S Proteins (10) and and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal MAP1S Primary Antibody for FACS, IHC (p) - ABIN651956
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
Show all 2 Pubmed References
Results suggested that microtubule associated protein 1S (MAP1S) were up-regulated among Crohn's disease (CD) patients and MAP1S-related autophagy inhibits apoptosis of intestinal epithelial cells (IECs) through Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway which might play a vital role in the protection of intestinal mucosal barrier and inhibition the progression of CD.
Autophagy defects in the degradation of lipid droplets triggered by the MAP1S deficiency may enhance the initiation and development of ccRCC and reduce the survival of ccRCC patients.
HDAC4 (show HDAC4 Antibodies) destabilizes MAP1S, suppresses autophagy flux and promotes the accumulation of mHTT aggregates.
Ddata underline the key role of MAP1S as a global regulator of microbutule stability and demonstrate a new primary function of MAP1S to regulate MT dynamics at the onset of cytokinesis.
results support a role for MAP1 (show MASP1 Antibodies) proteins in promoting efficient retrograde trafficking of HIV-1 by stimulating the formation of stable microtubules and mediating the association of HIV-1 cores with microtubules.
The PU.1-regulated MAP1S gene is implicated in neutrophil differentiation and autophagy control.
clarify roles of MAP1S in bridging microtubules and mitochondria with autophagic and mitophagic initiation, maturation, trafficking, and lysosomal clearance.
The amino acid sequence of VCY2IP-1 shows 59.3% and 41.9% homology to two human microtubule-associated proteins (MAPs), MAP1B (show MAP1B Antibodies) and MAP1A (show MAP1A Antibodies), respectively. VCY2IP-1 has an extensive homology to the N-terminus and C-terminus regions of MAP1B (show MAP1B Antibodies) and MAP1A (show MAP1A Antibodies)
Deletion mutagenesis indicated that C19ORF5 selectively binds double stranded DNA through its microtubule binding domain.
These results suggest that the interaction of SOCS3 (show SOCS3 Antibodies) with MAP1S and the integrity of the microtubule cytoskeleton play an important role in the negative regulation of SOCS3 (show SOCS3 Antibodies) on IL-6 (show IL6 Antibodies) signaling.
Depletion of MAP1S in mice leads to an accumulation of fibrosis-related proteins and the development of renal fibrosis in aged mice.
MAP1S-mediated autophagy plays an important role in maintaining mouse lifespan especially in the presence of extra amount of fibronectin (show FN1 Antibodies).
Data (including data from studies in knockout mice) suggest that Map1s interacts directly with MyD88 (myeloid differentiation primary response gene 88 (show MYD88 Antibodies)), a key adaptor of Toll (show TLR4 Antibodies)-like receptors, as phagocytosis of bacteria is initiated in macrophages.
Data establish a link between MAP1S-enhanced autophagy and suppression of genomic instability and tumorigenesis.
MAP8 is a novel microtubule associated protein (show SPAG5 Antibodies) containing two microtubule binding domains.
Axonal transport impairment may be a deleterious consequence of accumulated, toxic MAP8 protein.
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity).
microtubule-associated protein 1S
, BPY2 interacting protein 1
, BPY2-interacting protein 1
, VCY2 interacting protein 1
, VCY2-interacting protein 1
, microtubule-associated protein 8
, variable charge Y chromosome 2-interacting protein 1