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Involved in JNK signaling pathway (By similarity).. Additionally we are shipping MAPKBP1 Kits (4) and MAPKBP1 Proteins (3) and many more products for this protein.
Showing 10 out of 24 products:
Human Polyclonal MAPKBP1 Primary Antibody for ICC, IF - ABIN4332694
Lecat, Di Valentin, Somja, Jourdan, Fillet, Kufer, Habraken, Sadzot, Louis, Delvenne, Piette, Legrand-Poels: The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. in The Journal of biological chemistry 2012
We identified mutations in MAPKBP1 as a genetic cause of juvenile or late-onset and cilia-independent nephronophthisis.
JNKBP1 and NOD2 are co-expressed in the human intestinal epithelium and in immune cells recruited in the lamina propria, which suggests that JNKBP1 contributes to maintain NOD2-mediated intestinal immune homeostasis.
The Mapkbp1 protein could enhance the NF-kappaB activation induced by MAP kinase kinase kinase 7 and TNF Receptor-Associated Factor 2 , and could promote TNF Receptor-Associated Factor 2 polyubiquitination.
Involved in JNK signaling pathway (By similarity).
mitogen-activated protein kinase-binding protein 1
, mitogen-activated protein kinase binding protein 1
, JNK-binding protein 1
, mitogen activated protein kinase binding protein 1
, Jun N-terminal kinase binding protein 1
, Jun N-terminal kinase-binding protein 1