Natural Cytotoxicity Triggering Receptor 2 Proteins (NCR2)

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.. Additionally we are shipping Natural Cytotoxicity Triggering Receptor 2 Antibodies (60) and Natural Cytotoxicity Triggering Receptor 2 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NCR2 9436 O95944
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Top Natural Cytotoxicity Triggering Receptor 2 Proteins at

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Human Cells Human His tag 100 μg 14 to 16 Days
Escherichia coli (E. coli) Human His tag 100 μg 13 to 16 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human NCR2 Protein. 100 μg 11 to 18 Days

NCR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for Natural Cytotoxicity Triggering Receptor 2 (NCR2) Interaction Partners

Human Natural Cytotoxicity Triggering Receptor 2 (NCR2) interaction partners

  1. We therefore identified the NKp44 binding site to PCNA and further developed an NKp44-peptide-based agent that can inhibit tumor growth through interfering with the function of intracellular PCNA in the tumor cell.

  2. Increased expression of p44 natural killer cell receptor (NKp44 ) was associated earlier stages of diffuse large B-cell lymphoma (DLBCL).

  3. The regulation of T cell proliferation during HPIV3 infection is mediated via NK receptors NKp44 and NKp46 and involves the surface glycoprotein haemagglutinin-neuraminidase but not the fusion protein of the virus.

  4. Study identified a novel ligand for NKp44 on astrocytes. Expression of this novel ligand decreased with increasing HIV-3S peptide concentration and blocking this novel ligand decreased NK cell killing. NK cell killing of astrocytes was decreased when astrocytes were incubated with HIV-3S peptide. NKp44 has a protective effect on astrocytes from NK cell mediated killing during HIV infection and impact astrocyte's role.

  5. NKp44 and NKp30 splice variants profiles are tissue/condition specific and demonstrate similarity between placenta and cancerous tissues.

  6. NKp44-1 expression was significantly associated with poor survival of AML patients. Moreover, activation of PBMC from healthy controls showed co-dominant expression of NKp44-1 and NKp44-3, while primary NK clones show more diverse NKp44 splice variant profiles.

  7. On CD56(+) CD3(-) cells, NKp44 and NKp46 expressions were high in the acute hepatitis E patients, whereas NKp30, NKp44, NKp46 and NKG2D were high in the recovered individuals.

  8. demonstrated that the mitogen and iK562 exposure to peripheral blood mononuclear cells can significantly improve NK activity which is co-related to the higher expression of NKp44 and NKG2D

  9. NCR(+) ILC3 from skin and blood of psoriasis patients produced IL-22, which is regarded as a key driver of epidermal thickening, suggesting that NCR(+) ILC3 may participate in psoriasis pathology.

  10. Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  11. NKp44+ ILC3 are expressed in human skin and blood and may have a role in psoriasis pathogenesis

  12. Expression of NKp44 ligand by normal articular chondrocytes is not involved in their killing by unstimulated NK cells; however, it is responsible for anti-chondrocyte cytotoxicity mediated by long-term activated NK cells.

  13. MLL5 is a cellular ligand for the natural cytotoxicity receptor NKp44.

  14. Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation.

  15. Novel interaction between proliferating cell nuclear antigen and HLA I on the surface of tumor cells inhibits NK cell function through NKp44.

  16. triggering in RORgammat-positive innate lymphoid cells selectively activates a proinflammatory program

  17. While interaction of TLR2 with mycobacterial cell wall promotes activation of resting NK cells and IFN-gamma production, NKp44 interaction with its putative ligands could play a secondary role in maintaining cell activation

  18. Natural cytotoxicity receptors play a major role in the recognition by NK cells of cancer stem cells targets.

  19. These data show that the Kaposi's sarcoma-associated herpesvirus ORF54 product downregulates the NKp44 ligand and that the NKp44-NKp44 ligand signaling pathway contributes to antiviral immunity.

  20. a precise analysis of clinical data showed a correlation between decreased NCR expression and poor prognosis factors such as low haemoglobin level, high (>30x10(9) per litre) lymphocyte count or elevated C-reactive protein

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Protein Profile

Protein Summary

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Gene names and symbols associated with NCR2

  • uncharacterized LOC609023 (LOC609023)
  • natural cytotoxicity triggering receptor 2 (NCR2)
  • CD336 protein
  • dJ149M18.1 protein
  • LY95 protein
  • NK-p44 protein
  • NKP44 protein

Protein level used designations for NCR2

natural cytotoxicity triggering receptor 2 , NK cell activating receptor (NKp44) , NK cell-activating receptor , lymphocyte antigen 95 (activating NK-receptor; NK-p44) , lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44) , natural killer cell p44-related protein

609023 Canis lupus familiaris
693869 Macaca mulatta
100066291 Equus caballus
100137205 Papio anubis
100153074 Sus scrofa
9436 Homo sapiens
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