NKp44/NCR2 Protein (AA 19-130) (His tag)

Catalog No. ABIN5853466

Product Details

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Protein Type: Recombinant

Protein Characteristics: AA 19-130

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NKp44/NCR2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MSQAQSKAQV LQSVAGQTLT VRCQYPPTGS LYEKKGWCKE ASALVCIRLV TSSKPRTMAW TSRFTIWDDP DAGFFTVTMT DLREEDSGHY WCRIYRPSDN SVSKSVRFYL VVS

Purity: > 80 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Alternative Name: NCR2 (NCR2 Products)

Synonyms: CD336 Protein, LY95 Protein, NK-p44 Protein, NKP44 Protein, dJ149M18.1 Protein, uncharacterized LOC609023 Protein, natural cytotoxicity triggering receptor 2 Protein, LOC609023 Protein, NCR2 Protein

Background: NCR2 belongs to the natural cytotoxicity receptor (NCR) family and contains 1 Ig-like (immunoglobulin-like) domain. This protein interacts with TYROBP/DAP12 and is selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. NCR2 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Recombinant human NKP44 protein, fused to His-tag at N-terminus, was expressed in E.coli

Molecular Weight: 15.0 kDa (133aa)

NCBI Accession: NP_004819

UniProt: O95944