anti-Periplakin (PPL) Antibodies

The protein encoded by PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. Additionally we are shipping Periplakin Kits (11) and Periplakin Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPL 5493 O60437
PPL 302934  
PPL 19041 Q9R269
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Top anti-Periplakin Antibodies at

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-PPL Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (p), WB PPL Antibody (C-term) (ABIN658092) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the PPL antibody detected the PPL protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IP, WB Western Blot: Periplakin Antibody  - Detection of Mouse and Rat Periplakin/PPL by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. Antibodies: Affinity purified rabbit anti-Periplakin/PPL antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 0.1 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ICC, IHC, IP, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB Used in DAB staining on fromalin fixed paraffin- embedded ovary tissue 100 μg Log in to see 13 to 16 Days
Human Rabbit Un-conjugated WB Periplakin antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:250 dilution. Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775] - U87 xenograft. 0.1 mL Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using PPL antibody. Immunohistochemistry of paraffin-embedded rat kidney using PPL antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days

PPL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,

, , , , ,
Rat (Rattus)

Mouse (Murine)

More Antibodies against Periplakin Interaction Partners

Human Periplakin (PPL) interaction partners

  1. Letter: suggest periplakin autoimmunity may be involved in asthma pathogenesis.

  2. PPL overexpression inhibited the growth of colon cancer.

  3. Low serum periplakin is associated with urothelial carcinoma.

  4. Human gamma-delta T cells are activated by cytosolic interactions of BTN3A1 (show BTN3A1 Antibodies) with soluble phosphoantigens and the cytoskeletal adaptor periplakin.

  5. Loss of periplakin expression is associated with pathological stage and cancer-specific survival in patients with urothelial carcinoma of the urinary bladder.

  6. Annexin A9 (show ANXA9 Antibodies) and periplakin co-localise in the epidermis and annexin A9 (show ANXA9 Antibodies) is up-regulated in differentiating keratinocytes, but the epidermal annexin A9 (show ANXA9 Antibodies) expression does not require periplakin.

  7. Sciellin (show SCEL Antibodies), SPRR3 (show SPRR3 Antibodies), and periplakin transcripts were all upregulated (4.67-, 4.95-, 2.77-fold, respectively) by prolonged exposure to cyclic strain (24-72 h), but not at earlier time points.

  8. autoantibodies are detected in patients with paraneoplastic pemphigus

  9. This protein binds to protein kinase B (show AKT1 Antibodies).

  10. in spite of its high homology and structural similarity with envoplakin (show EVPL Antibodies), periplakin is functionally closer to the plakin proteins plectin (show PLEC Antibodies) and desmoplakin (show DSP Antibodies), and may function tissue-wide as a scaffolding protein in intermediate filament assembly

Mouse (Murine) Periplakin (PPL) interaction partners

  1. Data suggest that the primary role of periplakin may not relate to the physiology of the cornified cell envelope in epidermal keratinocytes but may reside in the challenges, which normal laboratory mice do not encounter.

  2. Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 (show MCHR1 Antibodies) by binding to the proximal segment of the receptor C-terminal tail

Periplakin (PPL) Antigen Profile

Protein Summary

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Gene names and symbols associated with anti-Periplakin (PPL) Antibodies

  • periplakin (PPL) antibody
  • periplakin (ppl) antibody
  • periplakin L homeolog (ppl.L) antibody
  • periplakin (Ppl) antibody
  • AW553870 antibody
  • cb180 antibody
  • im:7140067 antibody
  • im:7149519 antibody
  • sb:cb180 antibody

Protein level used designations for anti-Periplakin (PPL) Antibodies

periplakin , periplakin-like , 190 kDa paraneoplastic pemphigus antigen , 195 kDa cornified envelope precursor protein , 195kDa protein

408044 Gallus gallus
449936 Danio rerio
453893 Pan troglodytes
490021 Canis lupus familiaris
495053 Xenopus laevis
710266 Macaca mulatta
100069951 Equus caballus
100343940 Oryctolagus cuniculus
100407595 Callithrix jacchus
100460826 Pongo abelii
100512773 Sus scrofa
100547953 Meleagris gallopavo
100563033 Anolis carolinensis
100602203 Nomascus leucogenys
5493 Homo sapiens
522886 Bos taurus
302934 Rattus norvegicus
19041 Mus musculus
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