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The protein encoded by SMAD9 is a member of the SMAD family, which transduces signals from TGF-beta family members. Additionally we are shipping SMAD9 Proteins (7) and SMAD9 Kits (6) and many more products for this protein.
Showing 10 out of 81 products:
Human Polyclonal SMAD9 Primary Antibody for EIA, ELISA - ABIN251308
Shi, Massagué: Mechanisms of TGF-beta signaling from cell membrane to the nucleus. in Cell 2003
Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.
Case Report: hamartomatous olyposis and gastrointestinal ganglioneuromas with SMAD9 germline mutation that reduces PTEN expression.
a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show GARS Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).
ATP production by NaF (show IL8 Antibodies) promotes hypertrophy-like changes via activation of phospho-Smad8
TNF (show TNF Antibodies) activated NF-kappaB (show NFKB1 Antibodies) pathway and inhibited the phosphorylation of Smad 1 (show GARS Antibodies)/5/8 and BMP-2 (show BMP2 Antibodies)-induced osteoblastic differentiation in BMMSCs
CREBZF (show CREBZF Antibodies), a novel Smad8-binding protein.
Data suggest that Smads 1, 5 and 8 as potential prognostic markers and therapeutic targets for mTOR (show FRAP1 Antibodies) inhibition therapy of prostate cancer.
Endoglin (show ENG Antibodies) promotes transforming growth factor beta-mediated Smad 1 (show GARS Antibodies)/5/8 signaling and inhibits endothelial cell migration through its association with GIPC (show GIPC1 Antibodies)
Study described the first mutation in SMAD8 in a patient with IPAH, and suggested the involvement of SMAD8 in the pathogenesis of PAH.
5-HT (show DDC Antibodies) transactivates the serine kinase receptor, BMPR 1A (show BMPR1A Antibodies), to activate Smads 1/5/8 via Rho and Rho kinase (show ROCK1 Antibodies) in in bovine and human pulmonary artery smooth muscle cells
Sphingosine 1 phosphate also up-regulated runt-related transcription factor 2 (Runx2 (show RUNX2 Antibodies)) expression through S1PR2 (show S1PR2 Antibodies)/RhoA (show RHOA Antibodies)/ROCK/Smad1 (show SMAD1 Antibodies)/5/8 signaling.
BetA can enhance in vivo osteogenic potentials of BMP2 (show BMP2 Antibodies), possibly via stimulating Smad 1 (show SMAD1 Antibodies)/5/8 and p38 (show CRK Antibodies) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.
findings suggest that Smad9 is a new type of transcriptional regulator in BMP signaling.
The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (show BMP2 Antibodies)/Smad1 (show SMAD1 Antibodies)/5/8 and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathways.
Data indicate that PDGF (show PDGFA Antibodies)-AA promotes mesenchymal stem cel migration via bone morphogenetic protein 2 (BMP2 (show BMP2 Antibodies))-smad (show SMAD1 Antibodies) proteins smad1 (show SMAD1 Antibodies)/5/8 activation requires lysosome-mediated degradation of PDGF (show PDGFA Antibodies) alpha Receptor (PDGFRalpha).
our data suggest a pivotal role for canonical BMP signaling demonstrating distinguished nonoverlapping function of pSmad8 with pSmad1 and pSmad5 in hfSCs regulation and hair morphogenesis but a redundant role in adult hair progenitors differentiation.
Data show that HtrA1 (show HTRA1 Antibodies) is produced during osteoclastogenesis, and negatively regulates osteoblast differentiation, osteoblast differentiation and BMP2 (show BMP2 Antibodies)-induced Smad1 (show SMAD1 Antibodies)/5/8, ERK1/2 and p38 (show CRK Antibodies) phosphorylation in pre-osteoblasts.
FGF2 (show FGF2 Antibodies) inhibited BMP9 (show GDF2 Antibodies)-induced osteogenic differentiation by blocking BMP9 (show GDF2 Antibodies)-induced Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 (show ACVRL1 Antibodies) and ALK2 (show ACRV1 Antibodies) in mesenchymal stem cells.
a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.
MAD, mothers against decapentaplegic homolog 9
, Mothers against decapentaplegic-like protein 9
, mothers against decapentaplegic homolog 9
, SMAD family member 9
, mothers against decapentaplegic homolog 9-like
, MAD homolog 9
, Mothers against decapentaplegic, drosophila, homolog of, 9
, SMAD, mothers against DPP homolog 9
, mothers against DPP homolog 9
, SMAD 9
, SMAD, mothers against DPP 8
, TGF-beta signal transducer Smad8