anti-Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) Antibodies

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Additionally we are shipping SLC7A8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC7A8 23428 Q9UHI5
SLC7A8 84551 Q9WVR6
SLC7A8 50934 Q9QXW9
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Top anti-SLC7A8 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: SLC7A8 Sample Tissue: Human 293T Whole Cell Antibody Dilution: 1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SLC7A8 Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  SLC7A8  Sample Type:  Fetal Liver Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), IP, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IHC Immunohistochemistry: SLC7A8 Antibody [NBP2-49319] - Staining of human kidney shows cytoplasmic and membranous positivity in renal tubules. Immunohistochemistry-Paraffin: SLC7A8 Antibody  - Staining of human liver shows low expression as expected. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC208586 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SLC7A8 antibody (ABIN2453803), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SLC7A8 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SLC7A8. 0.1 mL Log in to see Available
$451.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC208586 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SLC7A8 antibody (ABIN2453804), and then analyzed by flow cytometry. Anti-SLC7A8 mouse monoclonal antibody (ABIN2453804) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC7A8 (RC208586). 0.1 mL Log in to see Available
$482.90
Details
Human Mouse Un-conjugated FACS, IHC, WB Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-SLC7A8mouse monoclonal antibody. (ABIN2452597, Dilution 1:50) 0.1 mL Log in to see Available
$451.00
Details
Human Mouse Un-conjugated FACS, IF HEK293T cells transfected with either pCMV6-ENTRY SLC7A8 (RC208586) (Red) or empty vector control plasmid (Blue) were immunostained with anti-SLC7A8 mouse monoclonal (ABIN2453648, Dilution 1:1,000), and then analyzed by flow cytometry. Anti-SLC7A8 mouse monoclonal antibody (ABIN2453648) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC7A8 (RC208586). 0.1 mL Log in to see Available
$451.00
Details
Human Mouse Un-conjugated FACS, IF, IP, IHC, WB HEK293T cells transfected with either pCMV6-ENTRY SLC7A8 (RC208586) (Red) or empty vector control plasmid (Blue) were immunostained with anti-SLC7A8 mouse monoclonal (ABIN2452328, Dilution 1:1,000), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SLC7A8 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SLC7A8. 0.1 mL Log in to see Available
$451.00
Details

More Antibodies against SLC7A8 Interaction Partners

Human Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

  1. The detergent-induced stabilization of the purified human 4F2hc (show SLC3A2 Antibodies)-LAT2 (show LAT2 Antibodies) complex presented here paves the way towards its crystallization and structure determination at high-resolution

  2. LAT2 (show LAT2 Antibodies) genes may play important roles in leiomyoma cell proliferation and regulate leiomyoma growth

  3. LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) were overexpressed in both pheochromocytoma and medullary thyroid carcinoma by comparison with normal tissues.

  4. LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) are present and functional in the syncytiotrophoblast MVM, whereas LAT2 (show LAT2 Antibodies) is also expressed in the BM and in the fetal capillary endothelium.

  5. Compared with the adult cerebral cortex, mRNAs encoding OATP1A2 (show SLCO1A2 Antibodies), OATP1C1 (show SLCO1C1 Antibodies), OATP3A1 (show SLCO3A1 Antibodies) variant 2, OATP4A1 (show OATP-E Antibodies), LAT2 (show LAT2 Antibodies) and CD98 (show SLC3A2 Antibodies) were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8 (show MCT8 Antibodies), MCT10 (show SLC16A10 Antibodies), OATP3A1 (show SLCO3A1 Antibodies) variant 1 and LAT1 (show LAT Antibodies) were similar.

  6. the interaction of CD98 (show SLC3A2 Antibodies)/LAT2 (show LAT2 Antibodies) with ICAM-1 (show ICAM1 Antibodies), found to be expressed to the basolateral domain, and the potential of such interaction on intracellular signal activation in Caco2-BBE (show ENO3 Antibodies) cell monolayers

  7. identify LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) as members of system L that mediate transmembrane movement of l-CSNO

  8. Genetic variation in LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) does not appear to be a major cause of inter-individual variability in pharmacokinetics and of adverse reactions to melphalan.

Mouse (Murine) Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

  1. distinct molecular LAT2-features determine bidirectional amino acid transport but only an unidirectional thyroid hormone (show PTH Antibodies) import.

  2. Circulating thyroid hormones, thyrotropin and thyroid hormone-responsive (show THRSP Antibodies) genes remained unchanged in Slc7a8(-/-) mice, possibly because of functional compensation by the thyroid hormone (show PTH Antibodies) transporter Mct8 (show MCT8 Antibodies), which is co-expressed in many cell types

  3. the aromatic amino acid diffusion pathway TAT1 (show SLC16A10 Antibodies) can control neutral amino acid efflux via neighboring exchanger LAT2-4F2hc (show SLC3A2 Antibodies), by recycling its aromatic influx substrates

  4. The positive effect of non-T cell activation linker (NTAL (show LAT2 Antibodies)) on Akt (show AKT1 Antibodies) phosphorylation and mast cell survival requires LAT (show LAT Antibodies).

  5. LAT1 (show SLC7A5 Antibodies), and LAT2 mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 (show Slco1a1 Antibodies) and NTCP (show SLC10A1 Antibodies) mRNAs were not.

SLC7A8 Antigen Profile

Protein Summary

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).

Gene names and symbols associated with SLC7A8

  • solute carrier family 7 member 8 (SLC7A8) antibody
  • solute carrier family 7 member 8 (Slc7a8) antibody
  • solute carrier family 7 member 8 L homeolog (slc7a8.L) antibody
  • solute carrier family 7 member 8 (slc7a8) antibody
  • solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b) antibody
  • 4F2LC-5 antibody
  • AA408822 antibody
  • lat2 antibody
  • Lat4 antibody
  • lpi-pc1 antibody
  • si:ch211-14a17.3 antibody
  • si:zc14a17.3 antibody
  • slc7a8 antibody
  • XAA2 antibody

Protein level used designations for SLC7A8

L-type amino acid transporter 2 , integral membrane protein E16H , large neutral amino acids transporter small subunit 2 , solute carrier family 7 (amino acid transporter, L-type), member 8 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 , cationic amino acid transporter y+ system , solute carrier family 7 member 8 , glycoprotein-associated amino acid transporter LAT2 , 4F2-LC5 , mLAT2 , solute carrier family 8 (cationic amino acid transporter, y+ system), member 7 , solute carrier family 7 (amino acid transporter light chain, L system), member 8 , zmp:0000000645 , zmp:0000000781

GENE ID SPECIES
23428 Homo sapiens
84551 Rattus norvegicus
380297 Xenopus laevis
394580 Xenopus (Silurana) tropicalis
452793 Pan troglodytes
490608 Canis lupus familiaris
536818 Bos taurus
713511 Macaca mulatta
100009408 Oryctolagus cuniculus
100134829 Sus scrofa
100172820 Pongo abelii
50934 Mus musculus
100007990 Danio rerio
100052453 Equus caballus
100717482 Cavia porcellus
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