anti-Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) Antibodies

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Additionally we are shipping SLC7A8 Proteins (4) and many more products for this protein.

Gene Name	GeneID	UniProt
SLC7A8	23428	Q9UHI5
SLC7A8	84551	Q9WVR6
SLC7A8	50934	Q9QXW9

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Top anti-SLC7A8 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2792072	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN1500964	Human	Mouse	Un-conjugated	IHC, IHC (p), WB	100 μL	Log in to see	11 to 14 Days	$507.83	Details
ABIN2781629	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$249.00	Details
ABIN1500960	Human	Mouse	Un-conjugated	FACS, IF, IHC, IHC (p), IP, WB	100 μL	Log in to see	11 to 14 Days	$507.83	Details
ABIN2744411	Human	Mouse	Un-conjugated	FACS, IF, IHC, IHC (p), IP	50 μL	Log in to see	11 to 14 Days	$484.00	Details
ABIN2571724	Human	Mouse	Un-conjugated	FACS, IHC, IHC (p), WB	100 μL	Log in to see	11 to 14 Days	$639.83	Details
ABIN2571723	Human	Mouse	Un-conjugated	FACS, IF, IHC, IHC (p), WB	100 μL	Log in to see	11 to 14 Days	$639.83	Details
ABIN2628428	Cow	Rabbit	Un-conjugated	IHC, IHC (p), WB	100 μg	Log in to see	11 to 14 Days	$639.83	Details
ABIN4354508	Human	Rabbit	Un-conjugated	IHC	0.1 mL	Log in to see	10 to 13 Days	$494.38	Details
ABIN2732182	Human	Mouse	Un-conjugated	FACS, WB	0.1 mL	Log in to see	2 to 3 Days	$451.00	Details

More product categories related to SLC7A8 Antibody

More Antibodies against SLC7A8 Interaction Partners

Human Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

The detergent-induced stabilization of the purified human 4F2hc-LAT2 complex presented here paves the way towards its crystallization and structure determination at high-resolution
LAT2 genes may play important roles in leiomyoma cell proliferation and regulate leiomyoma growth
LAT1 and LAT2 were overexpressed in both pheochromocytoma and medullary thyroid carcinoma by comparison with normal tissues.
LAT1 and LAT2 are present and functional in the syncytiotrophoblast MVM, whereas LAT2 is also expressed in the BM and in the fetal capillary endothelium.
Compared with the adult cerebral cortex, mRNAs encoding OATP1A2, OATP1C1, OATP3A1 variant 2, OATP4A1, LAT2 and CD98 were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8, MCT10, OATP3A1 variant 1 and LAT1 were similar.
the interaction of CD98/LAT2 with ICAM-1, found to be expressed to the basolateral domain, and the potential of such interaction on intracellular signal activation in Caco2-BBE cell monolayers
identify LAT1 and LAT2 as members of system L that mediate transmembrane movement of l-CSNO
Genetic variation in LAT1 and LAT2 does not appear to be a major cause of inter-individual variability in pharmacokinetics and of adverse reactions to melphalan.

Mouse (Murine) Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

distinct molecular LAT2-features determine bidirectional amino acid transport but only an unidirectional thyroid hormone import.
Circulating thyroid hormones, thyrotropin and thyroid hormone-responsive genes remained unchanged in Slc7a8(-/-) mice, possibly because of functional compensation by the thyroid hormone transporter Mct8, which is co-expressed in many cell types
In a neuronal cell model, y+,L and y+ transport systems are the predominant form of arginine uptake mechanisms and the transport of arginine is altered by membrane potential and redox factors.
the aromatic amino acid diffusion pathway TAT1 can control neutral amino acid efflux via neighboring exchanger LAT2-4F2hc, by recycling its aromatic influx substrates
System L functions as influx and/or efflux transport machinery displaying a greater propensity for the outward transport of large and small neutral amino acids.
The positive effect of non-T cell activation linker (NTAL) on Akt phosphorylation and mast cell survival requires LAT.
LAT1, and LAT2 mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 and NTCP mRNAs were not.

SLC7A8 Antigen Profile

Protein Summary

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).

Gene names and symbols associated with SLC7A8

solute carrier family 7 member 8 (SLC7A8) antibody
solute carrier family 7 member 8 (Slc7a8) antibody
solute carrier family 7 member 8 L homeolog (slc7a8.L) antibody
solute carrier family 7 member 8 (slc7a8) antibody
solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8) antibody
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8) antibody
solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b) antibody

4F2LC-5 antibody
AA408822 antibody
lat2 antibody
Lat4 antibody
lpi-pc1 antibody
si:ch211-14a17.3 antibody
si:zc14a17.3 antibody
slc7a8 antibody
XAA2 antibody

Protein level used designations for SLC7A8

L-type amino acid transporter 2 , integral membrane protein E16H , large neutral amino acids transporter small subunit 2 , solute carrier family 7 (amino acid transporter, L-type), member 8 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 , cationic amino acid transporter y+ system , solute carrier family 7 member 8 , glycoprotein-associated amino acid transporter LAT2 , 4F2-LC5 , mLAT2 , solute carrier family 8 (cationic amino acid transporter, y+ system), member 7 , solute carrier family 7 (amino acid transporter light chain, L system), member 8 , zmp:0000000645 , zmp:0000000781

GENE ID	SPECIES
23428	Homo sapiens
84551	Rattus norvegicus
380297	Xenopus laevis
394580	Xenopus (Silurana) tropicalis
452793	Pan troglodytes
490608	Canis lupus familiaris
536818	Bos taurus
713511	Macaca mulatta
100009408	Oryctolagus cuniculus
100134829	Sus scrofa
100172820	Pongo abelii
50934	Mus musculus
100007990	Danio rerio
100052453	Equus caballus
100717482	Cavia porcellus

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