SLC7A8 Products
(Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
Categories
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).
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Featured SLC7A8 Categories
SLC7A8 Antibodies
High quality antibodies with extensive validation data.
SLC7A8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC7A8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, IHC (p), IF, IP
Validations
- (5)
Cat. No.
ABIN1500960
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN6243302
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN525163
Quantity
100 μg
Datasheet
Datasheet
Recommended SLC7A8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320534
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320533
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3118920
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SLC7A8 products
: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." in: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).: "Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma." in: Brain tumor pathology, Vol. 34, Issue 4, pp. 179-181, (2018) (PubMed).
: "Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc, a System L Amino Acid Transporter." in: International journal of molecular sciences, Vol. 18, Issue 8, (2018) (PubMed).
: "Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 1, pp. 129-137, (2016) (PubMed).
Synonyms and alternative names related to SLC7A8
solute carrier family 7 member 8 (SLC7A8), solute carrier family 7 member 8 (Slc7a8), solute carrier family 7 member 8 L homeolog (slc7a8.L), solute carrier family 7 member 8 (slc7a8), solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b), 4F2LC-5, AA408822, LAT2, Lat2, lat2, Lat4, LPI-PC1, lpi-pc1, si:ch211-14a17.3, si:zc14a17.3, slc7a8, XAA2Protein level used designations for SLC7A8
- L-type amino acid transporter 2
- integral membrane protein E16H
- large neutral amino acids transporter small subunit 2
- solute carrier family 7 (amino acid transporter, L-type), member 8
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
- cationic amino acid transporter y+ system
- solute carrier family 7 member 8
- glycoprotein-associated amino acid transporter LAT2
- 4F2-LC5
- mLAT2
- solute carrier family 8 (cationic amino acid transporter, y+ system), member 7
- solute carrier family 7 (amino acid transporter light chain, L system), member 8
- zmp:0000000645
- zmp:0000000781
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