anti-Tyrosinase-Related Protein 1 (TYRP1) Antibodies

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway.

list all antibodies Gene Name GeneID UniProt
Anti-Human TYRP1 TYRP1 7306 P17643
Anti-Rat TYRP1 TYRP1 298182  
Anti-Mouse TYRP1 TYRP1 22178 P07147
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Top anti-Tyrosinase-Related Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 288 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Host: Rabbit <br /> Target Name: TYRP1 <br /> Sample Tissue: Human 721_BLane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5.0 µg/mL Lysate Quantity:.41 µg/lane/laneGel Concentration: 12 % 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Tyrp1 Antibody   Titration: 1.0 ug/ml   Positive Control: Rat Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TYRP1 Antibody Titration:  2.5ug/ml  Positive Control:  Jurkat cell lysate Host:  Mouse  Target Name:  TYRP1  Sample Tissue:  Mouse Liver  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Skin, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CATB Antibody (Center) (ABIN391549) in Y79 cell line lysates (35 µg/lane). CATB (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with CATB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB TYRP1 Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TYRP1 antibody detected the TYRP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit CF405M FACS, IF, IHC   100 μL Log in to see 3 to 4 Days
$209.23
Details
Human Rabbit CF®543 FACS, IF, IHC   100 μL Log in to see 3 to 4 Days
$209.23
Details

Top referenced anti-Tyrosinase-Related Protein 1 Antibodies

  1. Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for IF (p), IHC (p) - ABIN1714403 : Cui, Song, Geng, Ding, Qin, Fan, Dong, Geng: The expression of KRT2 and its effect on melanogenesis in alpaca skins. in Acta histochemica 2016 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for IHC, WB - ABIN2781815 : Horibe, Satoh, Shiota, Kumagai, Horike, Takemori, Uesato, Sugie, Obata, Kawahara, Nagaoka: Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells. in Journal of natural medicines 2013 (PubMed)

  3. Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for IHC, IHC (p) - ABIN4893177 : Abad, Wieërs, Colau, Wildmann, Delair, Dhote, Brézin, Kawakami, Coulie, van der Bruggen: Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. in Molecular vision 2014 (PubMed)

More Antibodies against Tyrosinase-Related Protein 1 Interaction Partners

Human Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. The rs387907171 SNP in TYRP1 exhibits strong allele frequency differences among islands in Northern Island Melanesia. Its absence from Bougainville, as well as the weak association with decreased hair color, indicates that additional alleles contribute to the blondism phenotype.

  2. TYRP1-dependent miR-16 (show GDE1 Antibodies) sequestration can also be overcome in vivo by using small oligonucleotides that mask miR-16 (show GDE1 Antibodies)-binding sites on TYRP1 mRNA.

  3. The mRNA of TYRP1 is now found to sequester the tumour suppressor miR-16 (show GDE1 Antibodies).

  4. DNA sequencing showed that the patient has carried compound heterozygous mutations of the tyrosinase related protein (TYRP1) gene, namely c.1214C>A (p.T405N) and c.1333dupG, which were inherited from his mother and father, respectively.

  5. Single nucleotide polymorphisms in TYRP1 gene is associated with multiple primary melanoma.

  6. Mutation in TYRP1 is associated with oculocutaneous albinism.

  7. Polymorphisms in 3'UTR (show UTS2R Antibodies) of TYRP1 mRNA can affect TYRP1 mRNA regulation by miR (show MLXIP Antibodies)-155 and its subsequent translation into protein. These SNPs can render TYRP1 mRNA and protein expression nonsusceptible to miR (show MLXIP Antibodies)-155 activity

  8. These data suggest that UVB-stimulated Ucn1 (show UCN Antibodies) contributes to TRP1 (show PRSS1 Antibodies) production via the transcription of both Nurr-1 (show NR4A2 Antibodies) and Nur77 (show NR4A1 Antibodies). Ucn1 (show UCN Antibodies), produced in melanoma cells, acts on melanoma cells themselves in an autocrine manner.

  9. These data indicate that galectin-3 (show LGALS3 Antibodies) is a regulatory component in melanin synthesis affecting the expression of Tyrp-1.

  10. p53 (show TP53 Antibodies) regulation by TRP2 (show DCT Antibodies) is not pervasive in melanoma.

Zebrafish Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. a mutation in tyrp1A, one of the two tyrp1 paralogs in zebrafish, causes melanophore death leading to a semi-dominant phenotype

  2. The Fugu tyrp1 promoter can direct transgene expression in a cell-type-specific manner in zebrafish. Our findings provide evidence supporting differential regulations of melanin-synthesizing genes in RPE (show RPE Antibodies) cells and the NCDM in zebrafish.

Fruit Fly (Drosophila melanogaster) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. TRP (show trpl Antibodies) de-phosphorylation affects the detection limit of oscillating light in photoreceptor cells.

  2. Data show that phosphorylation of most ransient receptor potential (TRP (show trpl Antibodies)) ion channel sites depends on the phototransduction cascade and the activity of the TRP (show trpl Antibodies).

  3. TRP (show trpl Antibodies) and TRPL (show trpl Antibodies) assemble exclusively as homomultimeric channels in their native environment.

  4. These results indicate that the Pain TRP (show trpl Antibodies) channels in the MBs (show NEU2 Antibodies) and IPCs control neuronal plasticity that is required for the formation of a certain type of long-lasting associative memory in Drosophila.

  5. Vesicle exocytosis depends on cacophony, TRP (show trpl Antibodies) and TRPL (show trpl Antibodies).

  6. members of the TRP (show trpl Antibodies) family are "special assignment" channels, which are recruited to diverse signaling pathways.

  7. Single amino acid change in the fifth transmembrane segment of the TRP (show trpl Antibodies) Ca2 (show CA2 Antibodies)+ channel causes massive degeneration of photoreceptors.

  8. Paper briefly overviews current knowledge of TRP and its mammalian homologues as non-voltage-gated Ca2+ channels that are constitutively active or gated by a multitude of stimuli; thus TRPs may play divergent roles in cell pathophysiology.

  9. Data show that a substantial reduction of the TRP (show trpl Antibodies) channel protein by RNA interference completely rescues neuronal degeneration and significantly improves the light-elicited responses of the eye.

  10. TRP (show trpl Antibodies) has independent channel and scaffolding roles

Cow (Bovine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R (show MSHR Antibodies) genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle.

Pig (Porcine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. A 6-bp deletion in the TYRP1 gene causes the brown colouration phenotype in Chinese indigenous pigs.

Rabbit Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. we identified some genes that are related to fur formation, including Tyrosinase-related protein 1 (TYRP1) and Tyrosinase (TYR (show TYR Antibodies)), as well as genes with unknown functions.

  2. A mutation in exon 2 of the TYRP1 gene leads to a premature stop codon at position 190 of the deduced amino acid sequence. Genotyping 203 rabbits of 32 different breeds identified this mutation only in brown Havana rabbits.

Mouse (Murine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Genetic modulators of IOP thus may be independently identified using the full array of BXD mice without concern for the presence of transillumination defect or mutations in Typr1 and/or Gpnmb.

  2. the results from the present study demonstrate that the MA extract increases melanogenesis through the upregulation of TRP-1 (show TRPC1 Antibodies) protein expression by post-transcriptional control in B16F10 cells

  3. Studied upregulation by Kaliziri extract of tyrosinase (show TYR Antibodies), TRP-1 (show TRPC1 Antibodies), TRP-2 (show DCT Antibodies) and MITF (show MITF Antibodies) expression in murine B16 melanoma cells.

  4. The SNARE (show VTI1B Antibodies) machinery composed of VAMP7 (show VAMP7 Antibodies) on Tyrp1-containing vesicles and syntaxin-3 (show STX3 Antibodies) and SNAP23 (show SNAP23 Antibodies) on melanosomes regulates Tyrp1 trafficking to the melanosome in melanocytes.

  5. Addition of a TRP-1 (show TRPC1 Antibodies)-directed monoclonal antibody to the treatment protocol for B16F10 skin melanoma mediates eradication of subcutaneous lesions.

  6. analysis of tyrosinase-related protein 1 in mouse melanocytes at early embryonic stage

  7. GILT (show IFI30 Antibodies)-deficient mice have an increase in TRP1 (show TRPC1 Antibodies)-specific regulatory T (Treg) cells compared with TRP1 (show TRPC1 Antibodies)-deficient mice, and depletion of Treg cells partially restores the ability of GILT (show IFI30 Antibodies)-deficient TRP1 (show TRPC1 Antibodies)-specific CD4 (show CD4 Antibodies)(+) T cells to induce vitiligo (show MITF Antibodies).

  8. The Tyrp1b mutation modifies the pathways and gene networks in which Tyrp1 functions.

  9. DNA vaccination with a melanoma-shared antigen Trp1 (show TRPC1 Antibodies), combined with systemic TGF-beta (show TGFB1 Antibodies) blockade during the perioperative period of primary tumor resection, confers protection against B16 melanoma.

  10. both the Rab32 (show RAB32 Antibodies)/38 binding activity and VAMP7 (show VAMP7 Antibodies) binding activity of Varp (show ANKRD27 Antibodies) are essential for trafficking of Tyrp1 in melanocytes but activation of Rab21 (show RAB21 Antibodies) by the VPS9 domain is not necessary for Tyrp1 trafficking

Tyrosinase-Related Protein 1 (TYRP1) Antigen Profile

Protein Summary

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Gene names and symbols associated with TYRP1

  • tyrosinase related protein 1 (TYRP1) antibody
  • tyrosinase-related protein 1b (tyrp1b) antibody
  • transient receptor potential (trp) antibody
  • tyrosinase-related protein 1 (Tyrp1) antibody
  • tyrosinase-related protein 1 L homeolog (tyrp1.L) antibody
  • tyrosinase-related protein 1 (tyrp1) antibody
  • tyrosinase-related protein 1 (LOC100136490) antibody
  • tyrosinase-related protein 1 (tyrp-1) antibody
  • tyrosinase-related protein 1a (tyrp1a) antibody
  • tyrosinase related protein 1 (Tyrp1) antibody
  • 559 antibody
  • b antibody
  • b-PROTEIN antibody
  • brown antibody
  • CAS2 antibody
  • CATB antibody
  • CG7875 antibody
  • Dmel\\CG7875 antibody
  • DmTRP antibody
  • dTrp antibody
  • gene B antibody
  • GP75 antibody
  • hm:zeh0659 antibody
  • idl-B antibody
  • isa antibody
  • OCA3 antibody
  • Trp antibody
  • TRP-1 antibody
  • TRP1 antibody
  • Tyrp antibody
  • tyrp-1 antibody
  • TYRP1 antibody
  • zgc:100893 antibody

Protein level used designations for TYRP1

5,6-dihydroxyindole-2-carboxylic acid oxidase , DHICA oxidase , catalase B , glycoprotein 75 , melanoma antigen gp75 , oca3 , tyrosinase-related protein 1 , TRP-1 , TRP1 , tyrosinase-related protein-1 , CG7875-PA , CG7875-PB , Cosens-Manning mutant , INAD localization-B , transient photreceptor potential , transient receptor potential protein , trp-PA , trp-PB , tyrosine phosphatase 1, same as B (Brown) , 5,6-dihydroxyindole-2-carboxylic acid oxidase-like , brown locus protein , iris stromal atrophy

GENE ID SPECIES
7306 Homo sapiens
437022 Danio rerio
395913 Gallus gallus
43542 Drosophila melanogaster
282105 Bos taurus
298182 Rattus norvegicus
380184 Xenopus laevis
403479 Canis lupus familiaris
464994 Pan troglodytes
549230 Xenopus (Silurana) tropicalis
554339 Felis catus
574065 Sus scrofa
714646 Macaca mulatta
100033886 Equus caballus
100034666 Ovis aries
100136490 Salmo salar
100136925 Salmo salar
100218715 Taeniopygia guttata
100342170 Oryctolagus cuniculus
100396341 Callithrix jacchus
100460406 Pongo abelii
100590830 Nomascus leucogenys
22178 Mus musculus
100333145 Danio rerio
100717475 Cavia porcellus
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