anti-Tyrosinase-Related Protein 1 (TYRP1) Antibodies

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Additionally we are shipping Tyrosinase-Related Protein 1 Proteins (12) and Tyrosinase-Related Protein 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TYRP1 7306 P17643
TYRP1 298182  
TYRP1 22178 P07147
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Top anti-Tyrosinase-Related Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 290 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Host: Rabbit  Target Name: TYRP1  Sample Tissue: Human 721_BLane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5.0 µg/mL Lysate Quantity:.41 µg/lane/laneGel Concentration: 12 % 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Tyrp1 Antibody   Titration: 1.0 ug/ml   Positive Control: Rat Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TYRP1 Antibody Titration:  2.5ug/ml  Positive Control:  Jurkat cell lysate Host:  Mouse  Target Name:  TYRP1  Sample Tissue:  Mouse Liver  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CATB Antibody (Center) (ABIN391549) in Y79 cell line lysates (35 µg/lane). CATB (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with CATB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Skin, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TYRP1 /gp75 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other ... 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Goat Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (p) Flow Cytometry: TRP1 Antibody  - analysis of paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody. Immunocytochemistry/Immunofluorescence: TRP1 Antibody  - analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml). 100 μg Log in to see 7 to 9 Days
$446.35
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: TYRP1 Antibody  - Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles. Immunohistochemistry-Paraffin: TYRP1 Antibody  - Staining of human skin shows distinct cytoplasmic positivity in melanocytes. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Mouse Un-conjugated IHC, WB Western Blot: TYRP1 Antibody (CL4923)  - Western blot analysis in human cell line SK-MEL-30. Immunohistochemistry: TYRP1 Antibody (CL4923)  - Staining of human skin shows strong cytoplasmic immunoreactivity in melanocytes. 100 μL Log in to see 10 to 13 Days
$494.38
Details
Human Mouse Un-conjugated IHC (p), WB Western Blot: TYRP1 Antibody (CL4906)  - Western blot analysis in human cell line SK-MEL-30. Immunohistochemistry: TYRP1 Antibody (CL4906)  - Staining of human skin shows strong cytoplasmic immunoreactivity in melanocytes. 100 μL Log in to see 10 to 13 Days
$494.38
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$493.17
Details

Top referenced anti-Tyrosinase-Related Protein 1 Antibodies

  1. Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for IF (p), IHC (p) - ABIN1714403 : Cui, Song, Geng, Ding, Qin, Fan, Dong, Geng: The expression of KRT2 and its effect on melanogenesis in alpaca skins. in Acta histochemica 2016 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for IHC, WB - ABIN2781815 : Horibe, Satoh, Shiota, Kumagai, Horike, Takemori, Uesato, Sugie, Obata, Kawahara, Nagaoka: Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells. in Journal of natural medicines 2013 (PubMed)

  3. Human Polyclonal Tyrosinase-Related Protein 1 Primary Antibody for FACS, IHC (p) - ABIN391549 : Jensen, Petterson, Halle, Aaberg-Jessen, Kristensen: Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo. in BMC cancer 2018 (PubMed)

More Antibodies against Tyrosinase-Related Protein 1 Interaction Partners

Human Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. The rs387907171 SNP in TYRP1 exhibits strong allele frequency differences among islands in Northern Island Melanesia. Its absence from Bougainville, as well as the weak association with decreased hair color, indicates that additional alleles contribute to the blondism phenotype.

  2. TYRP1-dependent miR-16 sequestration can also be overcome in vivo by using small oligonucleotides that mask miR-16-binding sites on TYRP1 mRNA.

  3. The mRNA of TYRP1 is now found to sequester the tumour suppressor miR-16.

  4. DNA sequencing showed that the patient has carried compound heterozygous mutations of the tyrosinase related protein (TYRP1) gene, namely c.1214C>A (p.T405N) and c.1333dupG, which were inherited from his mother and father, respectively.

  5. Single nucleotide polymorphisms in TYRP1 gene is associated with multiple primary melanoma.

  6. Mutation in TYRP1 is associated with oculocutaneous albinism.

  7. Polymorphisms in 3'UTR of TYRP1 mRNA can affect TYRP1 mRNA regulation by miR-155 and its subsequent translation into protein. These SNPs can render TYRP1 mRNA and protein expression nonsusceptible to miR-155 activity

  8. These data suggest that UVB-stimulated Ucn1 contributes to TRP1 production via the transcription of both Nurr-1 and Nur77. Ucn1, produced in melanoma cells, acts on melanoma cells themselves in an autocrine manner.

  9. These data indicate that galectin-3 is a regulatory component in melanin synthesis affecting the expression of Tyrp-1.

  10. p53 regulation by TRP2 is not pervasive in melanoma.

  11. Due to mutation in Tyrp1 protein, it became more rigid and might disturb the structural conformation and catalytic function of the structure and might also play a significant role in inducing oculocutaneous albinism type III.

  12. in human melanoma HMV-II cells both CRF and Ucn1 regulate TRP1 gene expression via Nurr-1/Nur77 production, independent of pro-opiomelanocortin or alpha-melanocyte-stimulating hormone stimulation.

  13. High TYRP1/S100B mRNA expression in lymph node metastases from melanoma patients is associated with unfavourable clinical outcome.

  14. We report four Pakistani albinism mutations, including three SLC45A2 alleles and one 22-nucleotide deletion in TYRP1.

  15. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease.

  16. identifed an arginine-to-cysteine change at a highly conserved residue in TYRP1 as a major determinant of blond hair in Solomon Islanders; this missense mutation predicted to affect catalytic activity of TYRP1 and causes blond hair through a recessive mode of inheritance

  17. By using a population-based material of high-risk melanoma cases, we demonstrate a significant effect of both MC1R red hair color (RHC) variants and an ASIP haplotype, but could not replicate an association with postulated risk SNPs of TYR and TYRP1.

  18. We used the first ranked gene, tyrosinase-related protein 1 (TYRP1), further measured its expression in the validation population by real-time PCR and found it to be significantly correlated with distant metastasis-free survival.

  19. two novel mutations in TYRP1 gene in two Chinese patients with oculocutaneous albinism type 3

  20. Case Report: Report a Japanese girl with oculocutaneous albinism type 3 and novel mutations in TYRP1 gene.

Zebrafish Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. a mutation in tyrp1A, one of the two tyrp1 paralogs in zebrafish, causes melanophore death leading to a semi-dominant phenotype

  2. The Fugu tyrp1 promoter can direct transgene expression in a cell-type-specific manner in zebrafish. Our findings provide evidence supporting differential regulations of melanin-synthesizing genes in RPE cells and the NCDM in zebrafish.

Cow (Bovine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle.

Pig (Porcine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. A 6-bp deletion in the TYRP1 gene causes the brown colouration phenotype in Chinese indigenous pigs.

Rabbit Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. we identified some genes that are related to fur formation, including Tyrosinase-related protein 1 (TYRP1) and Tyrosinase (TYR), as well as genes with unknown functions.

  2. A mutation in exon 2 of the TYRP1 gene leads to a premature stop codon at position 190 of the deduced amino acid sequence. Genotyping 203 rabbits of 32 different breeds identified this mutation only in brown Havana rabbits.

Tyrosinase-Related Protein 1 (TYRP1) Antigen Profile

Protein Summary

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Gene names and symbols associated with TYRP1

  • tyrosinase related protein 1 (TYRP1) antibody
  • tyrosinase-related protein 1b (tyrp1b) antibody
  • tyrosinase-related protein 1 (Tyrp1) antibody
  • tyrosinase-related protein 1 L homeolog (tyrp1.L) antibody
  • tyrosinase-related protein 1 (tyrp1) antibody
  • tyrosinase-related protein 1 (LOC100136490) antibody
  • tyrosinase-related protein 1 (tyrp-1) antibody
  • tyrosinase-related protein 1a (tyrp1a) antibody
  • tyrosinase related protein 1 (Tyrp1) antibody
  • b antibody
  • b-PROTEIN antibody
  • brown antibody
  • CAS2 antibody
  • CATB antibody
  • GP75 antibody
  • hm:zeh0659 antibody
  • isa antibody
  • OCA3 antibody
  • TRP antibody
  • TRP-1 antibody
  • TRP1 antibody
  • Tyrp antibody
  • tyrp-1 antibody
  • TYRP1 antibody
  • zgc:100893 antibody

Protein level used designations for TYRP1

5,6-dihydroxyindole-2-carboxylic acid oxidase , DHICA oxidase , catalase B , glycoprotein 75 , melanoma antigen gp75 , oca3 , tyrosinase-related protein 1 , TRP-1 , TRP1 , tyrosinase-related protein-1 , tyrosine phosphatase 1, same as B (Brown) , 5,6-dihydroxyindole-2-carboxylic acid oxidase-like , brown locus protein , iris stromal atrophy

GENE ID SPECIES
7306 Homo sapiens
437022 Danio rerio
395913 Gallus gallus
282105 Bos taurus
298182 Rattus norvegicus
380184 Xenopus laevis
403479 Canis lupus familiaris
464994 Pan troglodytes
549230 Xenopus (Silurana) tropicalis
554339 Felis catus
574065 Sus scrofa
714646 Macaca mulatta
100033886 Equus caballus
100034666 Ovis aries
100136490 Salmo salar
100136925 Salmo salar
100218715 Taeniopygia guttata
100342170 Oryctolagus cuniculus
100396341 Callithrix jacchus
100460406 Pongo abelii
100590830 Nomascus leucogenys
22178 Mus musculus
100333145 Danio rerio
100717475 Cavia porcellus
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