PK-11195
Catalog No. ABIN1027793
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Quick Overview for PK-11195 (ABIN1027793)
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Purpose
- Mitochondrial Benzodiazepine receptor ligand
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Characteristics
- Mitochondrial benzodiazepine receptor ligand.
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Purity
- >98 %
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Chemical Name
- N-sec-Butyl-1-(2-chlorophenyl)-N-methyl-3-isoquinolinecarboxamide
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Formula
- C21H21CIN2O
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Solubility
- Soluble to 75 mM in ethanol and to 100 mM in DMSO
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Comment
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Source: Synthetic.
Appearance: White Crystals -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R68- Possible risk of irreversible effects
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Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R68- Possible risk of irreversible effects
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Storage
- -20 °C
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Background
- PK-11195 is an isoquinoline carboxamide which binds selectively to the peripheral benzodiazepine receptor (PBR). It has a high affinity for the PBR in all species. It has also been successfully used in PET scans to visualize brain inflammation in patients with neuronal damage.
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Molecular Weight
- 352.86
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CAS-No
- 85532-75-8
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