Antibiotic A-23187
Catalog No. ABIN1027799
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Quick Overview for Antibiotic A-23187 (ABIN1027799)
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Purpose
- Ca2+ ionophore
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Characteristics
- Ca2+ ionophore.
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Purity
- >98 %
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Chemical Name
- 5-(Methylamino)-2-({(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)-2-propanyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid, A23187, Calcimycin
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Formula
- C29H37N3O6
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Solubility
- Soluble to 10 mM in ethanol and to 50 mM in DMSO
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Comment
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Source: Synthetic.
Appearance: White Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Handling Advice
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Storage
- -20 °C
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Background
- A23187 is a mobile ion-carrier that forms stable complexes with divalent cations. It has antibiotic properties against gram positive bacteria and funghi. It also acts as divalent cation ionophore, that is used to increase intracellular calcium levels in intact cells. It also induces apoptosis in some cells and prevents it in others.
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Molecular Weight
- 523.63
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CAS-No
- 52665-69-7
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