Nigericin
Catalog No. ABIN1027803
$253.20
Plus shipping costs $50.00
Shipping to:
United States
Delivery in 3 to 5 Business Days
Quick Overview for Nigericin (ABIN1027803)
-
-
Purpose
- NALP3 activator
-
Characteristics
- Induces rapid intracellular acidification.
-
Purity
- >98 %
-
Chemical Name
- (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-metho xy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid
-
Formula
- C40H67NaO11
-
Solubility
- Soluble to 50 mM in DMSO and 20 mM in ethanol
-
-
-
-
Comment
-
Source: Synthetic.
Appearance: White to off-white Solid -
Restrictions
- For Research Use only
-
-
-
Format
- Solid
-
Precaution of Use
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
-
Handling Advice
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
-
Storage
- -20 °C
-
-
-
Background
- Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.
-
Molecular Weight
- 746.94
-
CAS-No
- 28643-80-3
-
-
You are here:
