Fumonisin B1

Catalog No. ABIN1027813

Quick Overview for Fumonisin B1 (ABIN1027813)

Product Details

Purpose: Ceramide synthase inhibitor

Characteristics: Blocks sphingolipid biosynthesis.

Purity: >98 %

Chemical Name: 2,2'-{(19-Amino-11,16,18-trihydroxy-5,9-dimethyl-6,7-icosanediyl)bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid

Formula: C34H59NO15

Solubility: Soluble to 10 mM in DMSO

Application Details

Comment:

Source: Synthetic.
Appearance: Beige Solid

Restrictions: For Research Use only

Handling

Format: Solid

Precaution of Use: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281

Handling Advice: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281

Storage: -20 °C

Target Details

Background: Fumonisin B1 is the most prevalent member of a family of toxins. It is hepatotoxic and nephrotoxic in all animal species. It occupies the space and electrostatic interactions of both sphinganine and fatty acyl-CoA. Due to this mechanism of action, it has toxic effects in humans such as neural tube defects, esophageal cancer, acute mycotoxicosis, and various other carcinogenic effects. Another effect of exposure to FB1 is apoptosis.

Molecular Weight: 721.83

CAS-No: 116355-83-0