N,N-Dimethylsphingosine
Catalog No. ABIN1027815
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Quick Overview for N,N-Dimethylsphingosine (ABIN1027815)
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Purpose
- Kinase inhibitor
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Characteristics
- Inhibits sphingosine kinase.
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Purity
- >98 %
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Chemical Name
- (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol
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Formula
- C20H41NO2
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Solubility
- Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
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Comment
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Source: Synthetic.
Appearance: White to off-white waxy solid, or viscous oil -
Restrictions
- For Research Use only
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Format
- Oil
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Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
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Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
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Storage
- -20 °C
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Background
- N,N-dimethylsphingosine is a potent and specific inhibitor of sphingosine kinase. It is a natural metabolite of sphiongosine in some cancel cell lines and tissues. It also induces apoptosis, but it is not an inhibitor of protein kinase C.
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Molecular Weight
- 327.6
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CAS-No
- 119567-63-4
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